DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG3927 and Sf1

DIOPT Version :9

Sequence 1:	NP_611681.1	Gene:	CG3927 / 37576	FlyBaseID:	FBgn0034739	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_001104261.1	Gene:	Sf1 / 22668	MGIID:	1095403	Length:	639	Species:	Mus musculus

Alignment Length:	232	Identity:	57/232 - (24%)
Similarity:	106/232 - (45%)	Gaps:	43/232 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 PSELTEKQNQDQPTYQ---PRLNEVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVYSTGRIP 65
            |....::....:|.|.   .|||....:....|:.||..|..|  :.||              .|
Mouse    73 PPNPEDRSPSPEPIYNSEGKRLNTREFRTRKKLEEERHTLITE--MVAL--------------NP 121

  Fly    66 GKEPFADVYQQKPMKIIQKVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRD 130
            ..:|.|| |:....::..||.:|.:::|:.||.|.::||:||:|:.:::|.:.||:|:|:.|:::
Mouse   122 DFKPPAD-YKPPATRVSDKVMIPQDEYPEINFVGLLIGPRGNTLKNIEKECNAKIMIRGKGSVKE 185

  Fly   131 ----RNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYL-----IPDDND 186
                |...:.|....:|.:|.:             .|.....:..|:.:||..|     .|:|.:
Mouse   186 GKVGRKDGQMLPGEDEPLHALV-------------TANTMENVKKAVEQIRNILKQGIETPEDQN 237

  Fly   187 DVWHEQQRELMEMNPKSAKKSNGLNMAPYRSNFDKAI 223
            |:...|.|||..:|....:..|.: :.|::|:..::|
Mouse   238 DLRKMQLRELARLNGTLREDDNRI-LRPWQSSETRSI 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3927	NP_611681.1	SF1_like-KH	83..201	CDD:239088	34/126 (27%)
Sf1	NP_001104261.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..44
		Nuclear localization signal. /evidence=ECO:0000255	15..19
		MSL5	17..257	CDD:227503	53/213 (25%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	65..94		3/20 (15%)
		ZnF_C2HC	278..293	CDD:197667
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	325..584
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.731683	Normalized mean entropy	S1317
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.760