Protein Alignment CG3927 and Qki

DIOPT Version :10

• Sequence 1: NP_611681.1
• Gene: CG3927 / 37576
• FlyBaseID: FBgn0034739
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_001152989.1
• Gene: Qki / 19317
• MGIID: 97837
• Length: 341
• Species: Mus musculus
• Alignment Length: 214
• Identity: 63/214 - (29%)
• Similarity: 109/214 - (50%)
• Gaps: 38/214 - (17%)

  Fly     9 EKQNQDQPTYQPRLNEVAQKFLADLDAERKRLSAEFPLCAL------LIDESVDRVYSTGRIPGK 67
            |.:.:::|...|       .:|..|..::|.:|:....|.:      |:||.:.||       .|
Mouse     4 EMETKEKPKPTP-------DYLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEISRV-------RK 54

  Fly    68 EPFADVYQQKPMK-----------IIQ---KVFVPVNKFPKFNFTGKILGPKGNSLRRLQEETHC 118
            :.:.|.......|           |:|   |::|||.::|.|||.|:||||:|.:.::|:.||.|
Mouse    55 DMYNDTLNGSTEKRSAELPDAVGPIVQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGC 119

  Fly   119 KIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDLFLEVSAVAPPAECYARIAYALAEIRKYLIP- 182
            ||:::|:.||||:.|||:.|  |.|.:.||::||.:.::..........::..|:.|::|.|:|
Mouse   120 KIMVRGKGSMRDKKKEEQNR--GKPNWEHLNEDLHVLITVEDAQNRAEIKLKRAVEEVKKLLVPA 182

  Fly   183 -DDNDDVWHEQQRELMEMN 200
             :..|.:...|..||..:|
Mouse   183 AEGEDSLKKMQLMELAILN 201

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3927	NP_611681.1	KH-I_KHDRBS	77..178	CDD:411812	40/114 (35%)
Qki	NP_001152989.1	STAR_dimer	10..64	CDD:435414	14/67 (21%)
		Qua1 domain, involved in homodimerization. /evidence=ECO:0000250|UniProtKB:Q17339	11..82		16/84 (19%)
		KH-I_Hqk	81..183	CDD:411893	41/103 (40%)
		Qua2 domain, involved in RNA binding. /evidence=ECO:0000250|UniProtKB:Q96PU8	182..213		5/20 (25%)
		PHA03247	<211..314	CDD:223021
		SH3-binding	276..279
		Quaking_NLS	312..341	CDD:435421
		Nuclear localization signal. /evidence=ECO:0000269|PubMed:10506177, ECO:0000269|PubMed:29021242	324..330