DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG3927 and Khdrbs1

DIOPT Version :9

Sequence 1:	NP_611681.1	Gene:	CG3927 / 37576	FlyBaseID:	FBgn0034739	Length:	270	Species:	Drosophila melanogaster
Sequence 2:	NP_569089.1	Gene:	Khdrbs1 / 117268	RGDID:	621459	Length:	443	Species:	Rattus norvegicus

Alignment Length:	178	Identity:	77/178 - (43%)
Similarity:	116/178 - (65%)	Gaps:	1/178 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 EVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVY-STGRIPGKEPFADVYQQKPMKIIQKVFV 87
            |...|:|.:|.||:..|...|.....|:...::::. ...:...:|.:.|::..|.||:.::|.:
  Rat    98 EPENKYLPELMAEKDSLDPSFTHAMQLLSVEIEKIQKGESKKDDEENYLDLFSHKNMKLKERVLI 162

  Fly    88 PVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDL 152
            ||.::|||||.||||||:||:::||||||..||.:.|:.||||:.||||||..|||:||||:.||
  Rat   163 PVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDL 227

  Fly   153 FLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMN 200
            .:.:....||.|.||.:|:|:.|::|:|:||..||:..||..||..:|
  Rat   228 HVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQEQFLELSYLN 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG3927	NP_611681.1	SF1_like-KH	83..201	CDD:239088	63/118 (53%)
Khdrbs1	NP_569089.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..95
		Involved in homodimerization. /evidence=ECO:0000250\|UniProtKB:Q07666	100..260		69/159 (43%)
		Qua1	102..153	CDD:406639	10/50 (20%)
		KH-I	152..257	CDD:412160	57/104 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	280..317
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	326..345
		Interaction with HNRNPA1. /evidence=ECO:0000250\|UniProtKB:Q07666	351..443
		Sam68-YY	366..415	CDD:406871
		Interaction with ZBTB7A. /evidence=ECO:0000250\|UniProtKB:Q07666	400..420
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	411..443
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348940
Domainoid	1	1.000	54	1.000	Domainoid score	I10913
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	168	1.000	Inparanoid score	I4063
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012406at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8931
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.900