Protein Alignment CG3927 and KHDRBS1

DIOPT Version :10

• Sequence 1: NP_611681.1
• Gene: CG3927 / 37576
• FlyBaseID: FBgn0034739
• Length: 270
• Species: Drosophila melanogaster
• Sequence 2: NP_006550.1
• Gene: KHDRBS1 / 10657
• HGNCID: 18116
• Length: 443
• Species: Homo sapiens
• Alignment Length: 178
• Identity: 77/178 - (43%)
• Similarity: 116/178 - (65%)
• Gaps: 1/178 - (0%)

  Fly    24 EVAQKFLADLDAERKRLSAEFPLCALLIDESVDRVY-STGRIPGKEPFADVYQQKPMKIIQKVFV 87
            |...|:|.:|.||:..|...|.....|:...::::. ...:...:|.:.|::..|.||:.::|.:
Human    98 EPENKYLPELMAEKDSLDPSFTHAMQLLTAEIEKIQKGDSKKDDEENYLDLFSHKNMKLKERVLI 162

  Fly    88 PVNKFPKFNFTGKILGPKGNSLRRLQEETHCKIVIKGRNSMRDRNKEEELRSSGDPRYAHLHKDL 152
            ||.::|||||.||||||:||:::||||||..||.:.|:.||||:.||||||..|||:||||:.||
Human   163 PVKQYPKFNFVGKILGPQGNTIKRLQEETGAKISVLGKGSMRDKAKEEELRKGGDPKYAHLNMDL 227

  Fly   153 FLEVSAVAPPAECYARIAYALAEIRKYLIPDDNDDVWHEQQRELMEMN 200
            .:.:....||.|.||.:|:|:.|::|:|:||..||:..||..||..:|
Human   228 HVFIEVFGPPCEAYALMAHAMEEVKKFLVPDMMDDICQEQFLELSYLN 275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3927	NP_611681.1	KH-I_KHDRBS	77..178	CDD:411812	55/100 (55%)
KHDRBS1	NP_006550.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..96
		Involved in homodimerization. /evidence=ECO:0000305|PubMed:26758068	100..260		69/159 (43%)
		Qua1	102..153	CDD:465079	10/50 (20%)
		KH-I_KHDRBS1	152..257	CDD:411896	57/104 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	280..316
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..346
		Interaction with HNRNPA1. /evidence=ECO:0000269|PubMed:17371836	351..443
		Sam68-YY	366..415	CDD:465182
		Interaction with ZBTB7A. /evidence=ECO:0000269|PubMed:24514149	400..420
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	411..443