Protein Alignment dnr1 and frmd3

DIOPT Version :10

• Sequence 1: NP_001261137.1
• Gene: dnr1 / 37575
• FlyBaseID: FBgn0260866
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_001072510.1
• Gene: frmd3 / 779965
• XenbaseID: XB-GENE-1011845
• Length: 585
• Species: Xenopus tropicalis
• Alignment Length: 215
• Identity: 53/215 - (24%)
• Similarity: 94/215 - (43%)
• Gaps: 19/215 - (8%)

  Fly     1 MWCIVNLPNGTQQAVKWDPKANGQECLEKVCRAMNIICEMEYFGLEHWTPNQKESQTRQWINLRN 65
            |.|.:.|.:.|:.:........||..|:.:|...|:: |.:|||:....|.::    |.|::...
 Frog    16 MRCTIRLLDDTEISFNIQRDTKGQFLLDYICNHYNLL-EKDYFGIRFVDPEKQ----RHWLDPSK 75

  Fly    66 RLSGDSGSSGSGIQLMLALRVKFW--VPVHFILQESVRNLFYMQARRDLLEGRLTAPDWSGAAKL 128
            .::....|..   ...:..||||:  .|:. |.:|..|.|.|:|.:||:..|||.. .::.||.|
 Frog    76 PVAKQMKSHP---PYTMCFRVKFYPHEPLK-IKEELTRYLLYLQIKRDIFHGRLLC-CFADAAFL 135

  Fly   129 AALLCQADGLRF--NESSLKADCPMRMRRELAQQQQQQQQQAQQHRLEQQRKEKEHVLSFKKRRL 191
            .|.:.||:...:  :|......|..::   ..:|.|:.:::..:....:.|.:...|..|  ..|
 Frog   136 GACIVQAEIGDYDPDEHPDNYICDFKI---FPKQSQKLERKIVEIHKNELRGQSPSVSEF--NLL 195

  Fly   192 SKQKSMEHIEVCTLPAASTT 211
            .|..|:|...|...|...:|
 Frog   196 LKAHSLETYGVDPHPCKDST 215

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnr1	NP_001261137.1	Ubl1_cv_Nsp3_N-like	1..89	CDD:475130	20/87 (23%)
		FERM_M	91..>148	CDD:459788	19/58 (33%)
		FERM_C_MYLIP_IDOL	325..435	CDD:270016
		RING-HC_IAPs	545..583	CDD:438173
frmd3	NP_001072510.1	FERM_F1_FRMD3	16..96	CDD:340622	20/87 (23%)
		FERM_M	100..209	CDD:459788	30/115 (26%)
		FERM_C_FRMD3_FRMD5	190..293	CDD:270013	8/28 (29%)
		FA	307..352	CDD:462582