Protein Alignment dnr1 and mylipb

DIOPT Version :9

• Sequence 1: NP_001261137.1
• Gene: dnr1 / 37575
• FlyBaseID: FBgn0260866
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_001073491.1
• Gene: mylipb / 565911
• ZFINID: ZDB-GENE-061027-67
• Length: 464
• Species: Danio rerio
• Alignment Length: 632
• Identity: 167/632 - (26%)
• Similarity: 250/632 - (39%)
• Gaps: 187/632 - (29%)

  Fly     1 MWCIVNLPNGTQQAVKWDPKANGQECLEKVCRAMNIICEMEYFGLEHWTPNQKESQTRQWINLRN 65
            |.|.:..|:.....|:.||||||::.|.|:|:.|.|| |::||||: :|..:.||   .|:||||
Zfish     1 MLCHITRPDSVVLEVEVDPKANGEDILNKICQKMGII-EVDYFGLQ-FTGTKGES---LWMNLRN 60

  Fly    66 RLSGDSGSSGSGIQLMLALRVKFWVPVHFILQESVRNLFYMQARRDLLEGRLTAPDWSGAAKLAA 130
            |:..:.....   ...|.|||||:|..|.||||..|:||.|..:.::::|.|.. |...|.:|.|
Zfish    61 RICQEVDCVS---PCRLRLRVKFFVEPHLILQEQTRHLFLMHVKEEIIKGSLRL-DAEQAIELCA 121

  Fly   131 LLCQADGLRFNESSLKADCPMRMRRELAQQQQQQQQQAQQHRLEQQRKEKEHVLSFKKRRLSKQK 195
            ||.||:...:.:::.|
Zfish   122 LLAQAEFGDYKQNTAK------------------------------------------------- 137

  Fly   196 SMEHIEVCTLPAASTTSCSLQPSPSASASASASASASASASTSACSQTHSNSSSSSPSNSSSQTG 260
                  .|
Zfish   138 ------YC--------------------------------------------------------- 139

  Fly   261 LDERLASNPLRVYEEYFMQPSCEGEPPADYLRQIAVEHGKLAKLQMSLKTAKYWLLKSIQDLEGY 325
                        |.:.:.|     :|..|.:..|:::|..|.  .:|..:|:|..|:.:..|..|
Zfish   140 ------------YSQIYGQ-----DPSHDTINTISLKHKSLE--GVSQASAEYQALQLVSSLTYY 185

  Fly   326 GEELFSGVTTNESATRCDIAVGAHGITVCRGG----EKQSIPFGAIAAAKSLRRTFKLEYVDDHN 386
            |.|..  ...:....:..|.||..|:.||:..    |:...|  .|..|....|...:....|:.
Zfish   186 GVEWH--FARDSEGQQLLIGVGQEGLFVCKSDFTPIERLMYP--VIQMATQSGRNVYVTITKDNG 246

  Fly   387 DRKELEIKLPKQPIAAGLYRSITERHAFYVCDKVRGVVTNQFTRDLKGTIASMFM-ENTELGKRY 450
            |...|..|......|.||||:|||.||||.||.|...|..|::||.||.:||:|: |:.:|||||
Zfish   247 DSVVLLFKFVSPSAANGLYRAITEIHAFYRCDTVMSTVKMQYSRDFKGHLASLFLNESIDLGKRY 311

  Fly   451 VFDIQHTCREVHDQARRTLHERGGDLVAEGAEGCSAVAGGLGASAVGEPGVSPWAMALTTGAGGS 515
            :||||.|.:||:|:.||.|...|                    .:|...|:|...:..|
Zfish   312 IFDIQRTSKEVYDRTRRALFNAG--------------------VSVNGRGISRSLLRQT------ 350

  Fly   516 MAGKIDLAIREK----EAREAAIERCVDTRISEAMQCKICMDRAINTVFNPCCHVIACAQCAARC 576
               |:|   ||:    :.||..:.:....|:.||:.|.:|.::.|:..|.||.|:..|..||::.
Zfish   351 ---KVD---REERMCVDCRETHVLKEKLQRLQEALTCALCCEQEISAAFCPCGHMFCCYNCASQL 409

  Fly   577 SNCPNCRVKITSVVKIYLPPELRTSQTGSGATTTSSSSIMGDGQVEE 623
            ..||.||.::..|..:|||  ...|..|.....|::|.:...|..|:
Zfish   410 QCCPVCRSEVDRVQHVYLP--TCASLLGLAEAKTTNSVLRRTGISED 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnr1	NP_001261137.1	B41	3..>143	CDD:214604	55/139 (40%)
		FERM_N	5..67	CDD:286467	27/61 (44%)
		FERM_M	93..>143	CDD:278785	19/49 (39%)
		FERM_C_MYLIP_IDOL	325..435	CDD:270016	38/113 (34%)
		zf-C3HC4_3	544..589	CDD:290631	16/44 (36%)
mylipb	NP_001073491.1	B41	3..190	CDD:214604	72/326 (22%)
		FERM_N	5..68	CDD:286467	28/67 (42%)
		FERM_M	85..190	CDD:278785	36/236 (15%)
		FERM_C_MYLIP_IDOL	185..295	CDD:270016	38/113 (34%)
		zf-C3HC4_3	377..422	CDD:290631	16/44 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586519
Domainoid	1	1.000	104	1.000	Domainoid score	I6652
eggNOG	1	0.900	-	-		E1_28NMI
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	246	1.000	Inparanoid score	I3258
OMA	1	1.010	-	-		QHG50100
OrthoDB	1	1.010	-	-		D1340284at2759
OrthoFinder	1	1.000	-	-		FOG0005564
OrthoInspector	1	1.000	-	-		otm24863
orthoMCL	1	0.900	-	-		OOG6_108913
Panther	1	1.100	-	-	O	PTHR23280
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X5201
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	13	12.770