Protein Alignment dnr1 and mylip

DIOPT Version :9

• Sequence 1: NP_001261137.1
• Gene: dnr1 / 37575
• FlyBaseID: FBgn0260866
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_001017059.2
• Gene: mylip / 549813
• XenbaseID: XB-GENE-949814
• Length: 445
• Species: Xenopus tropicalis
• Alignment Length: 603
• Identity: 166/603 - (27%)
• Similarity: 247/603 - (40%)
• Gaps: 177/603 - (29%)

  Fly     1 MWCIVNLPNGTQQAVKWDPKANGQECLEKVCRAMNIICEMEYFGLEHWTPNQKESQTRQWINLRN 65
            |.|.|..|:.....|:.|.||||::||.:||:.:.|| |.:||||: ::.|:.|:   .|:||||
 Frog     1 MLCYVTRPDAVVMEVEVDAKANGEDCLNQVCKRLGII-EGDYFGLQ-FSGNKGEN---LWLNLRN 60

  Fly    66 RLSGDSGSSGSGI-QLMLALRVKFWVPVHFILQESVRNLFYMQARRDLLEGRLTAPDWSGAAKLA 129
            |:|    ....|: ...|.|:|||:|..|.||||..|::|::..:.|||.|||.... :.|.:|:
 Frog    61 RIS----QQMDGLAPFRLKLKVKFFVEPHLILQEQTRHMFFLHIKEDLLAGRLQCSP-AQAVELS 120

  Fly   130 ALLCQADGLRFNESSLKADCPMRMRRELAQQQQQQQQQAQQHRLEQQRKEKEHVLSFKKRRLSKQ 194
            |||.|
 Frog   121 ALLAQ------------------------------------------------------------ 125

  Fly   195 KSMEHIEVCTLPAASTTSCSLQPSPSASASASASASASASASTSACSQTHSNSSSSSPSNSSSQT 259
              ||:                               ...|.:|:.
 Frog   126 --MEY-------------------------------GDYSVNTAT-------------------- 137

  Fly   260 GLDERLASNPLRVYEEYFMQPSCEGEPPADYLRQIAVEHGKLAKLQMSLKTAKYWLLKSIQDLEG 324
                            |.:|..|..:.....|..|..:|..|..|  |..:.:|..|:.:..||.
 Frog   138 ----------------YSLQDLCGKDIDTAALESIIAKHKSLEGL--SQASGEYQFLQIVSTLEN 184

  Fly   325 YGEELFSGVTTNESATRCDIAVGAHGITVCRGGEKQS----IPFGAIAAAKSLRRTFKLEYVDDH 385
            ||.|..|  ..:....:..:.:|..||::|:  |..|    |.:..|..|....:...|....:.
 Frog   185 YGVEWHS--VRDAEGQKLIVGIGPEGISLCK--EDFSPINRITYPVIQMATQSGKNVYLTITKES 245

  Fly   386 NDRKELEIKLPKQPIAAGLYRSITERHAFYVCDKVRGVVTNQFTRDLKGTIASMFM-ENTELGKR 449
            .:...|..|:.....|:||||:|||.||||.||.|...|..|::|||||.:||.|: :|..:||:
 Frog   246 GNSLVLLFKVVSTRAASGLYRAITETHAFYRCDTVTNAVMMQYSRDLKGHLASFFLNDNINVGKK 310

  Fly   450 YVFDIQHTCREVHDQARRTLHERG-GDLVAEGAEGCSAVAGGLGASAVGEPGVSPWAMALTTGAG 513
            |||||:.|.:||:|.|||.|:..| .|||:           |.|.|   ||. ||    |.|...
 Frog   311 YVFDIRRTSKEVYDHARRALYNAGIVDLVS-----------GSGHS---EPS-SP----LKTSES 356

  Fly   514 GSMAGKID-LAIREKEAREAAIERCVDTRISEAMQCKICMDRAINTVFNPCCHVIACAQCAARCS 577
            .......: |:.::.:|.:..:.     ::.|||.|.:|.:..||:.|.||.|::.|..||.:..
 Frog   357 NMNCNSCESLSCQQTKALQEKLR-----KLKEAMLCMLCCEEEINSAFCPCGHMVCCEGCATQLQ 416

  Fly   578 NCPNCRVKITSVVKIYLP 595
            :||.||..:..|..::||
 Frog   417 SCPVCRASVEHVQHVFLP 434

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnr1	NP_001261137.1	B41	3..>143	CDD:214604	55/140 (39%)
		FERM_N	5..67	CDD:286467	26/61 (43%)
		FERM_M	93..>143	CDD:278785	19/49 (39%)
		FERM_C_MYLIP_IDOL	325..435	CDD:270016	37/113 (33%)
		zf-C3HC4_3	544..589	CDD:290631	18/44 (41%)
mylip	NP_001017059.2	FERM_F1_MYLIP	1..81	CDD:340624	35/88 (40%)
		B41	5..190	CDD:214604	74/325 (23%)
		FERM_C_MYLIP_IDOL	185..295	CDD:270016	37/113 (33%)
		RING-HC_MYLIP	386..423	CDD:319437	14/36 (39%)
		RING-HC finger (C3HC4-type)	387..421	CDD:319437	13/33 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	52	1.000	Domainoid score	I11298
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8309
Inparanoid	1	1.050	239	1.000	Inparanoid score	I3274
OMA	1	1.010	-	-		QHG50100
OrthoDB	1	1.010	-	-		D1340284at2759
OrthoFinder	1	1.000	-	-		FOG0005564
OrthoInspector	1	1.000	-	-		oto104044
Panther	1	1.100	-	-	LDO	PTHR23280
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5236
SonicParanoid	1	1.000	-	-		X5201
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.110