Protein Alignment dnr1 and cora

DIOPT Version :10

• Sequence 1: NP_001261137.1
• Gene: dnr1 / 37575
• FlyBaseID: FBgn0260866
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_523791.2
• Gene: cora / 37205
• FlyBaseID: FBgn0010434
• Length: 1698
• Species: Drosophila melanogaster
• Alignment Length: 856
• Identity: 158/856 - (18%)
• Similarity: 263/856 - (30%)
• Gaps: 302/856 - (35%)

  Fly     5 VNLPNGTQQAVKWDPKANGQECLEKVCRAMNIICEMEYFGLEHWTPNQKESQTRQWINLRNRLS- 68
            |.|.:|:...|..|.||.|::.:..:|..:|:| |.:||||.:.||    :..|.|::|...:|
  Fly    36 VTLLDGSLLDVSIDRKAIGRDVINSICAGLNLI-EKDYFGLTYETP----TDPRTWLDLEKPVSK 95

  Fly    69 ---GDSGSSGSGIQLMLALRVKFWVPVHFILQESV-RNLFYMQARRDLLEGRLTAPDWSGAAKLA 129
               .|:..        |...|||:.|....|:|.: |....:|.|.|:|||||.. .:...|.|.
  Fly    96 FFRTDTWP--------LTFAVKFYPPEPSQLKEDITRYHLCLQVRNDILEGRLPC-TFVTHALLG 151

  Fly   130 ALLCQAD------------------GLRFNESSLKADCPMRMRRELAQQQQQQQQQAQQHRLEQQ 176
            :.|.|::                  .:..|:::...|..|.:.:   ..:.|...:|:.|.||..
  Fly   152 SYLVQSEMGDYDAEEMPTRAYLKDFKIAPNQTAELEDKVMDLHK---THKGQSPAEAELHYLENA 213

  Fly   177 RK--------------------------------------------------------------- 178
            :|
  Fly   214 KKLAMYGVDLHPAKDSEGVDIMLGVCASGLLVYRDKLRINRFAWPKILKISYKRHHFYIKIRPGE 278

  Fly   179 --EKEHVLSFK--KRRLSKQ--KS-MEHIEVCTL-------------------------PAASTT 211
              :.|..:.||  ..|.:|:  || :||.....|                         .|.||.
  Fly   279 FEQYESTIGFKLANHRAAKKLWKSCVEHHTFFRLMTPEPVSKSKMFPVFGSTYRYKGRTQAESTN 343

  Fly   212 SCSLQPSPSASASASASASASASASTSACSQTHSNSSSSSPSNSSSQTGLD-ERLASNPLRVYEE 275
            :...:..|..:.:.|.:...|.|....|.::....:..||..:.......| :..:.:|::..:|
  Fly   344 TPVDRTPPKFNRTLSGARLTSRSMDALALAEKEKVARKSSTLDHRGDRNADGDAHSRSPIKNKKE 408

  Fly   276 YFMQPSCEGEPPADYLRQIAVEHGKLAKLQMSLKTAKYWLLKSIQDLE-------------GYGE 327
                             :.|.:..||.:.:...|..|....:..::||             ..|.
  Fly   409 -----------------KDADKEAKLREKKQKEKEEKERKEREKRELEEKKKAEKAAKAALAAGA 456

  Fly   328 ELFSGVTTNE---SATRCDIAVGAHGITVCRGGEKQSIPFGAIAAAKSLRRTFKLEYVDDHNDRK 389
            ...:.|..|:   .:.:.|.:.|..|:.:...|.|        :.:.|..:..|    |.....|
  Fly   457 AAGAAVNGNDELNDSNKSDKSSGRRGVGIFSSGRK--------SKSGSPSKDGK----DKSGKDK 509

  Fly   390 ELEIKLPKQPIAAGLYRSITERH---AFYVCDKVRGVVTNQFTR------DLKGTIASMFMENTE 445
            :.|:......:.:||..:..:::   |.....|.||..|...||      |..|..:......|.
  Fly   510 DKEVGRLGLVVTSGLGDNQQDQNLDEAARNAAKNRGSTTPGVTRQYEYAVDNDGNTSPTRKSYTP 574

  Fly   446 LGKRYVFDIQHTCREVHDQARRTLHERGGDLVAEGAEGCSAVAGGLGASAVGEPGVSPWAMALTT 510
            .|.||..|         ..:|::           ||:              |:..:||
  Fly   575 GGFRYDQD---------PNSRKS-----------GAD--------------GQEQLSP------- 598

  Fly   511 GAGGSMAGKIDLAIREKEAREAAIERCVDT-----------------RISEAMQCKICMDRAINT 558
               .|...||.||.......|.|::...:.                 ::|...:.|:..|..::
  Fly   599 ---TSQQKKIGLAFNYAPGNENALKETAEKLKAGQLSPRTQDKLNRGQLSPKSRAKLLQDPLLS- 659

  Fly   559 VFNPCCHVIACAQCAARCSNCPNCRVKIT-SVVKIYLPPELRTSQTGSGATTTS----SSSIMGD 618
                                 |..|.|:. |.|.....| |..||..|.:.|..    ||...|.
  Fly   660 ---------------------PTTRAKLQGSAVDAAAVP-LSDSQKRSYSPTKGPQGYSSGAPGS 702

  Fly   619 GQ---------VEEQLLQQQLDEISAAPASLEAG-------------ADAGVGVGGMAVGAGAG- 660
            .:         :|.|...::...:..:.|.:.||             ...|.|..|.|..|.||
  Fly   703 YKPISDPTADFLESQRYNKEPGYVGPSKADVAAGLAGAAGSKKPGSPTKTGKGAPGAAAAAAAGA 767

  Fly   661 AGATGPGGQPK 671
            |||.....:||
  Fly   768 AGAAAAAAKPK 778

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnr1	NP_001261137.1	Ubl1_cv_Nsp3_N-like	1..89	CDD:475130	26/87 (30%)
		FERM_M	91..>148	CDD:459788	17/75 (23%)
		FERM_C_MYLIP_IDOL	325..435	CDD:270016	23/121 (19%)
		RING-HC_IAPs	545..583	CDD:438173	3/37 (8%)
cora	NP_523791.2	B41	34..224	CDD:214604	52/204 (25%)
		FERM_C_4_1_family	219..312	CDD:270005	9/92 (10%)
		FA	324..364	CDD:462582	5/39 (13%)
		4_1_CTD	1613..1698	CDD:461774