DRSC/TRiP Functional Genomics Resources

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Protein Alignment dnr1 and Frmd5

DIOPT Version :10

Sequence 1:NP_001261137.1 Gene:dnr1 / 37575 FlyBaseID:FBgn0260866 Length:696 Species:Drosophila melanogaster
Sequence 2:NP_609384.1 Gene:Frmd5 / 34398 FlyBaseID:FBgn0032225 Length:572 Species:Drosophila melanogaster


Alignment Length:383 Identity:80/383 - (20%)
Similarity:123/383 - (32%) Gaps:159/383 - (41%)


- Green bases have known domain annotations that are detailed below.


  Fly    16 KWDPKANGQECLEKVCRAMNIICEMEYFGLEHWTPNQKESQTRQWINLRNRLSGDSGSSGSGIQ- 79
            ::.|...|...||.:|..:. |.|.:||||.:    ...|:.|.|::|          |.|.|: 
  Fly    28 EFQPFHKGIYLLEYLCGELE-IKEKDYFGLRY----VDSSKQRHWLDL----------SKSIIKQ 77

  Fly    80 ------LMLALRVKFWVPVHFILQESVRNLFYMQARRDLLEGRLTAPDWSGAAKLAALLCQADGL 138
                  |:.:|||||:....|.|..:.|.:.|.|.:|||..|||.. ....||.|.||:.|.:..
  Fly    78 CKEMDPLLFSLRVKFYPADPFRLTGNARIMLYQQLKRDLRHGRLYC-SLGEAAALGALIVQEELG 141

  Fly   139 RFNE--------SSL-----KADCPMRMRRELAQQQQQQQ-----------------------QQ 167
            .:||        ||:     :.:|..:...||.::::..|                       ..
  Fly   142 DYNEDVHVGSYVSSIELALRQTECLEKKIIELHKKREPGQNLSLAMDEFLGIARGLETYGIDPHP 206

  Fly   168 AQQHRLEQQ----------------------------------------------RKEKEHVLSF 186
            .:.||..||                                              |:.|:|.:.|
  Fly   207 VKDHRGSQQYVGINNTGISTFVAGKRSQHFRWNEIHKINFEGKMFIAHLSYTDASREPKKHTVGF 271

  Fly   187 KKRRLSKQKSMEHIEVCTLPAAS--TTSCSLQPS-----PSASASASASASASASAST------- 237
            |               |...||.  ...|:::..     |::.::|..|.....|..|       
  Fly   272 K---------------CPTGAACRYLWRCAIEQMLFFTLPNSQSAAVISGGGFFSWGTKFRYTGR 321

  Fly   238 ----------SACSQTHSNSSSSS------PSNSSSQTG---------LDERLASNPL 270
                      :|..:..:||:||.      |:..||..|         |.....|.||
  Fly   322 TEREILTENINALREQKNNSNSSKRKASSVPATPSSPQGDLAQIRYSSLPRSTMSEPL 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
dnr1NP_001261137.1 Ubl1_cv_Nsp3_N-like 1..89 CDD:475130 23/79 (29%)
FERM_M 91..>148 CDD:459788 21/69 (30%)
FERM_C_MYLIP_IDOL 325..435 CDD:270016
RING-HC_IAPs 545..583 CDD:438173
Frmd5NP_609384.1 FERM_F1_FRMD3 12..93 CDD:340622 23/79 (29%)
FERM_M 104..205 CDD:459788 23/101 (23%)
FERM_C_FRMD3_FRMD5 186..294 CDD:270013 13/122 (11%)
FA 308..350 CDD:462582 7/41 (17%)
Blue background indicates that the domain is not in the aligned region.

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