Protein Alignment dnr1 and mylipa

DIOPT Version :9

• Sequence 1: NP_001261137.1
• Gene: dnr1 / 37575
• FlyBaseID: FBgn0260866
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: NP_956277.1
• Gene: mylipa / 335888
• ZFINID: ZDB-GENE-030131-7831
• Length: 472
• Species: Danio rerio
• Alignment Length: 622
• Identity: 168/622 - (27%)
• Similarity: 240/622 - (38%)
• Gaps: 218/622 - (35%)

  Fly     1 MWCIVNLPNGTQQAVKWDPKANGQECLEKVCRAMNIICEMEYFGLEHWTPNQKESQTRQWINLRN 65
            |.|.|..|:.....::.|.||||::||.||||.:.|| |::||||: ::.::.|:   .|:||||
Zfish     1 MLCHVTRPDAVVMEIEVDAKANGEDCLNKVCRKLGII-EVDYFGLQ-FSGSKGEN---LWLNLRN 60

  Fly    66 RLSGDSGSSGSGIQLM-------LALRVKFWVPVHFILQESVRNLFYMQARRDLLEGRLTAPDWS 123
            |:|          |.|       |.|||||:|..|.||||..|:||:|..:.||..|.|.... .
Zfish    61 RIS----------QQMDNLTPCRLRLRVKFFVEPHLILQEQTRHLFFMHVKEDLHRGHLRMCS-E 114

  Fly   124 GAAKLAALLCQADGLRFNESSLKADCPMRMRRELAQQQQQQQQQAQQHRLEQQRKEKEHVLSFKK 188
            .|.:|:|||.||:...:|:::.|
Zfish   115 QAQELSALLAQAEFGDYNQNTAK------------------------------------------ 137

  Fly   189 RRLSKQKSMEHIEVCTLPAASTTSCSLQPSPSASASASASASASASASTSACSQTHSNSSSSSPS 253
                                                                             
Zfish   138 ----------------------------------------------------------------- 137

  Fly   254 NSSSQTGLDERLASNPLRVYEEYFMQPSCEGEPPADYLRQIAVEHGKLAKLQMSLKTAKYWLLKS 318
                                  |:....|..||....:..|..:|..|..|  |..:.:|..|:.
Zfish   138 ----------------------YWYTELCGSEPNQTTINSIIAKHKALEGL--SQASVEYQALQL 178

  Fly   319 IQDLEGYGEELFSGVTTNESATRCDIAVGAHGITVCRGGEK--QSIPFGAIAAAKSLRRTFKLEY 381
            :..||.||.|..  ...:..|.|..|.||..||.:||....  ..|.:..|..|....::..|..
Zfish   179 VSSLEHYGVEWH--WARDAEAQRLAIGVGPEGIAICRDDFSLVNRISYPIIQIATQSGKSVYLTV 241

  Fly   382 VDDHNDRKELEIKLPKQPIAAGLYRSITERHAFYVCDKVRGVVTNQFTRDLKGTIASMFM-ENTE 445
            ..:.:|...|..||.....|:||||:|||.||||.||.|...|..|::||.||.:||:|: ||..
Zfish   242 TKESSDSVVLLFKLISNRAASGLYRAITETHAFYRCDTVTNAVMMQYSRDFKGHLASLFLNENIN 306

  Fly   446 LGKRYVFDIQHTCREVHDQARRTLHERG-GDLVA----------------EGAEGCSAVAGGLGA 493
            |||:|||||:.|.:||:|.|||.|:..| .|::|                |||..|
Zfish   307 LGKKYVFDIRRTSKEVYDYARRALYNAGIVDMMARPGERTPSNRSPSREQEGALDC--------- 362

  Fly   494 SAVGEPGVSPWAMALTTGAGGSMAGKIDLAIREKEAREAAIERCVDTRISEAMQCKICMDRAINT 558
                               ||....::   ::||.           .::.||:.|.:|.:..|:.
Zfish   363 -------------------GGCQQSRL---LQEKL-----------QKLREALLCMLCCEEEIDA 394

  Fly   559 VFNPCCHVIACAQCAARCSNCPNCRVKITSVVKIYLP 595
            .|.||.|::.|..|||:..:||.||.::..|..:|||
Zfish   395 AFCPCGHMVCCQNCAAQLQSCPVCRSEVEHVQHVYLP 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnr1	NP_001261137.1	B41	3..>143	CDD:214604	59/146 (40%)
		FERM_N	5..67	CDD:286467	26/61 (43%)
		FERM_M	93..>143	CDD:278785	21/49 (43%)
		FERM_C_MYLIP_IDOL	325..435	CDD:270016	40/111 (36%)
		zf-C3HC4_3	544..589	CDD:290631	17/44 (39%)
mylipa	NP_956277.1	B41	3..190	CDD:214604	76/333 (23%)
		FERM_N	5..68	CDD:286467	30/77 (39%)
		FERM_M	85..190	CDD:278785	38/236 (16%)
		FERM_C_MYLIP_IDOL	185..295	CDD:270016	40/111 (36%)
		zf-C3HC4_3	380..425	CDD:290631	17/44 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586518
Domainoid	1	1.000	104	1.000	Domainoid score	I6652
eggNOG	1	0.900	-	-		E1_28NMI
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H8309
Inparanoid	1	1.050	246	1.000	Inparanoid score	I3258
OMA	1	1.010	-	-		QHG50100
OrthoDB	1	1.010	-	-		D1340284at2759
OrthoFinder	1	1.000	-	-		FOG0005564
OrthoInspector	1	1.000	-	-		otm24863
orthoMCL	1	0.900	-	-		OOG6_108913
Panther	1	1.100	-	-	LDO	PTHR23280
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5236
SonicParanoid	1	1.000	-	-		X5201
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800