Protein Alignment dnr1 and Epb41l1

DIOPT Version :10

• Sequence 1: NP_001261137.1
• Gene: dnr1 / 37575
• FlyBaseID: FBgn0260866
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: XP_006498771.1
• Gene: Epb41l1 / 13821
• MGIID: 103010
• Length: 1602
• Species: Mus musculus
• Alignment Length: 785
• Identity: 151/785 - (19%)
• Similarity: 244/785 - (31%)
• Gaps: 253/785 - (32%)

  Fly     3 CIVNLPNGTQQAVKWDPKANGQECLEKVCRAMNIICEMEYFGLEHWTPNQKESQTRQWINLRNRL 67
            |.|.|.:.::...:.:....||...:.||..:|:: |.:||||   |....:|| :.|::....:
Mouse   111 CRVTLLDASEYECEVEKHGRGQVLFDLVCEHLNLL-EKDYFGL---TYCDADSQ-KNWLDPSKEI 170

  Fly    68 SGDSGSSGSGIQLMLALRVKFWVPVHFILQESV-RNLFYMQARRDLLEGRLTAPDWSGAAKLAAL 131
            .....||    ....|..|||:.|....|.|.: |....:|.|.|::.|||.. .:...|.|.:.
Mouse   171 KKQIRSS----PWNFAFTVKFYPPDPAQLTEDITRYYLCLQLRADIITGRLPC-SFVTHALLGSY 230

  Fly   132 LCQAD---------------GLRF--NESSLKADCPMRMRRELAQQQQQQQQ--------QAQQH 171
            ..||:               .|||  |::           |||.::..:..:        :|:.|
Mouse   231 AVQAELGDYDAEEHVGNYVSELRFAPNQT-----------RELEERIMELHKTYRGMTPGEAEIH 284

  Fly   172 RLEQQRKEKEHVLSFKKRRLSKQKSMEHIEVCTLPAA---------------------------S 209
            .||..:|     ||.....|...|..|.|::.....|                           |
Mouse   285 FLENAKK-----LSMYGVDLHHAKDSEGIDIMLGVCANGLLIYRDRLRINRFAWPKILKISYKRS 344

  Fly   210 TTSCSLQPSP----SASASASASASASASASTSACSQTHSNSSSSSP-----------------S 253
            .....::|..    .::.........||......|.:.|:.....||                 .
Mouse   345 NFYIKIRPGEYEQFESTIGFKLPNHRSAKRLWKVCIEHHTFFRLVSPEPPPKGFLVMGSKFRYSG 409

  Fly   254 NSSSQTGLDERLASNPLRVYE-----EYFMQPSCEGEPPADYLRQIAVEHGKLAKLQMSLKTAKY 313
            .:.:||.....|...|...:|     .|.|..|.:|   |::.|..:|...
Mouse   410 RTQAQTRQASALIDRPAPFFERSSSKRYTMSRSLDG---AEFSRPASVSEN-------------- 457

  Fly   314 WLLKSIQDLEGYGEELFSGVTTNESATRCDIAVGAHGITVCRGGEKQSIPFGAIAAAKSLRR--- 375
                  .|....|::            |.|.|..        ||.:.....|.:.....::.
Mouse   458 ------HDAGPDGDK------------REDDAES--------GGRRSEAEEGEVRTPTKIKELKP 496

  Fly   376 ------TFKLEYVDDHNDRKELEIKLPKQPIAAGLYRSITERHAFYV-----CDKVRGVVTNQFT 429
                  ..|.|::|     |..::.|..|.....|.|::.|.::..:     .|:.|.:.::..:
Mouse   497 EQETTPRHKQEFLD-----KPEDVLLKHQASINELKRTLKEPNSKLIHRDRDWDRERRLPSSPAS 556

  Fly   430 RDLKGTIASMFMENTELGKRYVFDIQHTCREVHDQARRTLHERGGDLVAEGAEGCSA-VAGGLGA 493
            ...|||     .|.....:|           :||.:::       |||...|.|... ....|.|
Mouse   557 PSPKGT-----PEKASEAQR-----------IHDTSQQ-------DLVPGTAAGLEVFTQKSLAA 598

  Fly   494 SAVGEPGVSPWAM------------ALTTGA------GGSMA--------GKIDLAIREKEAREA 532
            |..|.   ..|.:            .||..|      |.|:.        .|:|:.: :|...|.
Mouse   599 SPEGS---EHWVLIERVYTRPEDLGLLTVPATQREESGSSLTEILADGRLSKVDILV-DKFKVEV 659

  Fly   533 AIERCVDT-RISEAMQCK-ICMDRAINTVFNPCCHVIACAQCAARCSNCPNCRVKITSVVKIYLP 595
            |.|..|.. |.|...|.| |.......|:......:....:.|.|.:.       .||..|:
Mouse   660 ATEETVRAQRTSTQQQGKMIASPEGSETMREEDACLRGGPRDATRAAG-------YTSTDKL--- 714

  Fly   596 PELRTSQTGSGAT--------------TTSSSSIMGDGQVEEQLLQQQLDE-----ISAAPASLE 641
             :||.::..:|.|              |....:..|.|.|:.::|....|:     ....||..|
Mouse   715 -KLRNTRVSNGQTESHVELNKGLERPQTWGRLTAAGVGPVQGEVLSPASDKGGLQSFLLDPAQTE 778

  Fly   642 AGADA 646
            |.||:
Mouse   779 ARADS 783

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnr1	NP_001261137.1	Ubl1_cv_Nsp3_N-like	1..89	CDD:475130	22/85 (26%)
		FERM_M	91..>148	CDD:459788	18/74 (24%)
		FERM_C_MYLIP_IDOL	325..435	CDD:270016	19/123 (15%)
		RING-HC_IAPs	545..583	CDD:438173	6/38 (16%)
Epb41l1	XP_006498771.1	B41	111..300	CDD:214604	51/214 (24%)
		FERM_C_4_1_family	295..388	CDD:270005	11/92 (12%)
		FA	397..440	CDD:462582	6/42 (14%)
		SAB	505..>536	CDD:461285	9/35 (26%)
		4_1_CTD	1463..1588	CDD:461774