Protein Alignment dnr1 and dnr1

DIOPT Version :10

• Sequence 1: NP_001261137.1
• Gene: dnr1 / 37575
• FlyBaseID: FBgn0260866
• Length: 696
• Species: Drosophila melanogaster
• Sequence 2: XP_551203.5
• Gene: dnr1 / 1281563
• VectorBaseID: AGAMI1_002551
• Length: 603
• Species: Anopheles gambiae
• Alignment Length: 699
• Identity: 267/699 - (38%)
• Similarity: 362/699 - (51%)
• Gaps: 124/699 - (17%)

  Fly     1 MWCIVNLPNGTQQAVKWDPKANGQECLEKVCRAMNIICEMEYFGLEHWTP--------NQKESQT 57
            |||:|||||||...|:.|||...||||||||..:.||||.:||||   .|        :..|...
Mosquito     1 MWCLVNLPNGTTSGVQCDPKRISQECLEKVCADLGIICETDYFGL---IPVRDGDSVADVDEGTA 62

  Fly    58 RQWINLRNRL---SGDSGSSGSGIQLMLALRVKFWVPVHFILQESVRNLFYMQARRDLLEGRLTA 119
            :|||||||.|   :.|...     .::.:||||||||.|.|||.|||:||:||||::|.:|.|..
Mosquito    63 KQWINLRNPLHLYTNDRTH-----PIVFSLRVKFWVPAHLILQGSVRSLFFMQARQELFDGHLRP 122

  Fly   120 PDWSGAAKLAALLCQADGLRFNESSLKADCPMRMRRELAQQQQQQQQQAQQHRLEQQRKEKEHVL 184
            ..|:.||.|||||.||||.:::.:.:.:...|......:.....:::.|.| .|.:..|.|...|
Mosquito   123 SSWANAAYLAALLLQADGYKYDPAKVPSTSEMLPNGAASVTSSLERRPAAQ-GLRRPSKRKCSEL 186

  Fly   185 SFKKRRLSKQKSMEHIEVCTLPAASTTSCSLQPSPSASASASASASASASASTSACSQTHSNSSS 249
            ..|:..:|.|               |:..|..|.........|.|:...:|
Mosquito   187 ECKRGSVSSQ---------------TSGGSSVPHGGPQLDEGAPAAGGYTA-------------- 222

  Fly   250 SSPSNSSSQTGLDERLASNPLRVYEEY-FMQPSC----------EG--EP---PADYLRQIAVEH 298
                 :.||.|.|....:.|..:|..| .::|:.          ||  ||   ||::.:.||.||
Mosquito   223 -----AGSQLGGDGANGNAPKNIYHRYGALRPAFGDADEEEEQEEGTVEPVPQPANFYQLIAQEH 282

  Fly   299 GKLAKLQMSLKTAKYWLLKSIQDLEGYGEELFSGVTTNESATRCDIAVGAHGITVCRGGEKQSIP 363
            .||::::|:..:|:||||:.|..|.|||||:|.|||..|....|.|.|..||:|:.:..||.|:|
Mosquito   283 EKLSRIRMTATSAQYWLLEEICSLAGYGEEIFEGVTIAEPVVVCKIGVSPHGLTIVKDDEKYSVP 347

  Fly   364 FGAIAAAKSLRRTFKLEYVDDHNDRKELEIKLPKQPIAAGLYRSITERHAFYVCDKVRGVVTNQF 428
            |.|:.||||::|:|:|.|:::.::...:|:|||....||.|||:|||:|.||.|:.||.:||.||
Mosquito   348 FTAVKAAKSIKRSFRLTYMNESHEETYVELKLPNHRTAASLYRAITEKHVFYSCETVRPIVTTQF 412

  Fly   429 TRDLKGTIASMFMENTELGKRYVFDIQHTCREVHDQARRTLHERGGDLVAEGAEGCSAVAGGLGA 493
            .|||||||.|||.|:||||||||||||.|||||:|.||||||.||.::.....|.....|..|
Mosquito   413 IRDLKGTIVSMFNEDTELGKRYVFDIQRTCREVYDAARRTLHARGIEIAPSAVEHAETPAAAL-- 475

  Fly   494 SAVGEPGVSPWAMALTTGAGGSMAGKIDLAIREKEAREAAIERCVDTRISEAMQCKICMDRAINT 558
                                    |:::..:|.::.....:|:.:|.||.||:.|.||.|..|:|
Mosquito   476 ------------------------GRLEETLRSRQDASGQLEKLLDERIREAITCPICADGEIDT 516

  Fly   559 VFNPCCHVIACAQCAARCSNCPNCRVKITSVVKIYLPPELRTSQTGSGATTTSSSSIMGDGQVEE 623
            .|.||.|:.||..||.:|..||.||..|.|..||:|||.|: |:.|:.|:...|.
Mosquito   517 TFLPCGHMTACRACAVQCDRCPLCRANIESTSKIFLPPLLQ-SRKGTIASRRPSE---------- 570

  Fly   624 QLLQQQLDEISAAPASLEAGADAGVGVGGMAVGAGAGAGATGPGGQPKV 672
                      :||     ||...|.|.||..: |||.| :..|...|.|
Mosquito   571 ----------TAA-----AGVVGGAGGGGTEL-AGAVA-SKAPAAAPLV 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
dnr1	NP_001261137.1	Ubl1_cv_Nsp3_N-like	1..89	CDD:475130	45/98 (46%)
		FERM_M	91..>148	CDD:459788	29/56 (52%)
		FERM_C_MYLIP_IDOL	325..435	CDD:270016	55/109 (50%)
		RING-HC_IAPs	545..583	CDD:438173	18/37 (49%)
dnr1	XP_551203.5	None