DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gas and LOC679149

DIOPT Version :9

Sequence 1:	NP_611678.1	Gene:	gas / 37572	FlyBaseID:	FBgn0034736	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001094469.1	Gene:	LOC679149 / 679149	RGDID:	1591847	Length:	561	Species:	Rattus norvegicus

Alignment Length:	525	Identity:	166/525 - (31%)
Similarity:	239/525 - (45%)	Gaps:	101/525 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 TKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCTYAREKPMQRNS 101
            |..||::|:...........::|.|||||:||||.|||..|:.|..|.||||.|......:|...
  Rat    38 THIGQVRGKLDHVKDTKAGVHTFLGIPFAKPPVGPLRFAPPEAPEPWSGVRDGTSQPAMCLQNLD 102

  Fly   102 ITNAAEG-------------SEDCLYLNVYA-KRLESPKPLPVMVWIFGGGFQVGGASRELY-GP 151
            :.| |||             ||||||||:|| ........|||||||.|||...|.||  :| |.
  Rat   103 VIN-AEGLKEMKLKLPPVSMSEDCLYLNIYAPAHAHEGSNLPVMVWIHGGGLMTGMAS--MYDGS 164

  Fly   152 DYFMKHDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVF 216
            ...:..|:::|||.||:|||||.|..|:..:  ||.|..||:.|||||::|||.|.|:|:.:|:|
  Rat   165 LLTVNEDLVVVTIQYRLGVLGFFSTGDEHAR--GNWGYLDQVAALRWVQQNIAHFGGNPDRVTIF 227

  Fly   217 GESAGG--ASTHILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWPQRLGKELGYAGNLESEKE 279
            ||||||  .|||::  :..::||||.||::||.||..:..                       .:
  Rat   228 GESAGGTCVSTHVV--SPMSQGLFHGAIMESGVALLPYLI-----------------------AD 267

  Fly   280 LLEFFQQIPASKLAQYCNSIVTQ------EEQRDYEILAFAPVIE--PYVGDDCVIPKSQQEQLS 336
            ..|.|..:.|.  ...|.::.::      ..:.:.||||...|::  |.|.|...:|:..:|.|:
  Rat   268 TSEMFSTMVAK--VSGCEAMDSEALVHCLRAKSEAEILAINKVVQMVPAVVDGEFLPRHPKELLA 330

  Fly   337 SAWGNSIPMIIGGTSFEGLFSYRTTLDDPLYM--------LSA--FEAIIPKQVRDAIDKEELAE 391
            |.....:|.|||..:.|    |..|:  ||.|        ||.  .:||:.|.....:...|.::
  Rat   331 SEDFRPVPSIIGVNNDE----YGWTI--PLVMGTTQMIKELSRENLQAILKKTTAQLMLPLECSD 389

  Fly   392 MVRRLKKSYFDDPDRASMELYECLHILSIKNFWHDIHRTLLARLAYATNLPTYLYRF-------- 448
            ::........:||.....:..|.:     ::|...|....:|.. ..::.|.|.|.|
  Rat   390 LLMEEYMGDIEDPKTLQAQFTELM-----EDFMFVIPALQVAHF-QCSHAPVYFYEFQHQITFLK 448

  Fly   449 DMDSPHFNHYRILKCGKKVRGVCHADDISYMF-YGILSSKLDKNSPEYRTIERLVGMWTSFATTG 512
            |:..||..             ..|.|:|.::| |.....|.|....|.....|::..|.:||..|
  Rat   449 DIRPPHVK-------------ADHGDEIPFVFGYFFWDMKTDFTEEEKLLSRRMMKYWANFARHG 500

  Fly   513 DPNCE 517
            :||.|
  Rat   501 NPNSE 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	166/525 (32%)
gas	NP_611678.1	Aes	<117..>222	CDD:223730	52/106 (49%)
LOC679149	NP_001094469.1	COesterase	31..540	CDD:278561	166/525 (32%)
LOC679149	NP_001094469.1	Aes	<130..>233	CDD:223730	52/106 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336319
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.640