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Protein Alignment gas and BCHE

DIOPT Version :9

Sequence 1:	NP_611678.1	Gene:	gas / 37572	FlyBaseID:	FBgn0034736	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_000046.1	Gene:	BCHE / 590	HGNCID:	983	Length:	602	Species:	Homo sapiens

Alignment Length:	590	Identity:	162/590 - (27%)
Similarity:	262/590 - (44%)	Gaps:	110/590 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 LGTGQTKE---LATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRD 88
            :|...|::   :|||.|:::| ...|::.| ...:|.|||:||||:|.|||:.||..:.|..:.:
Human    23 IGKSHTEDDIIIATKNGKVRG-MNLTVFGG-TVTAFLGIPYAQPPLGRLRFKKPQSLTKWSDIWN 85

  Fly    89 CTYAREKPMQRNSITNAAEG-------------SEDCLYLNVYAKRLESPKP--LPVMVWIFGGG 138
            .|.......|  :|..:..|             |||||||||:   :.:|||  ..|::||:|||
Human    86 ATKYANSCCQ--NIDQSFPGFHGSEMWNPNTDLSEDCLYLNVW---IPAPKPKNATVLIWIYGGG 145

  Fly   139 FQVGGASRELYGPDYFMKHD-ILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKEN 202
            ||.|.:|..:|...:..:.: :::|::|||||.||||:|.... :.|||.||.||..||:||::|
Human   146 FQTGTSSLHVYDGKFLARVERVIVVSMNYRVGALGFLALPGNP-EAPGNMGLFDQQLALQWVQKN 209

  Fly   203 IASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWAT---QPDRKWPQRL 264
            ||:|.|:|:|:|:||||||.||..:.:.:..:..||.|||:||||....||.   ...|.....|
Human   210 IAAFGGNPKSVTLFGESAGAASVSLHLLSPGSHSLFTRAILQSGSFNAPWAVTSLYEARNRTLNL 274

  Fly   265 GKELGYAGNLESEKELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPK 329
            .|..|.  :.|:|.|:::..:               .::.|   |||.....:.||
Human   275 AKLTGC--SRENETEIIKCLR---------------NKDPQ---EILLNEAFVVPY--------- 310

  Fly   330 SQQEQLSSAWGNSIPMIIG-GTSFEGLFSYRTTLDDPLYMLSAFEAIIPKQVRDAIDKEELAEMV 393
                        ..|:.:. |.:.:|  .:.|.:.|.|..|..|:   ..|:...::|:|....:
Human   311 ------------GTPLSVNFGPTVDG--DFLTDMPDILLELGQFK---KTQILVGVNKDEGTAFL 358

  Fly   394 RRLKKSYFDDPDR--ASMELYECLHIL--SIKNF-----------WHDIHRTLLARLAYATNLPT 443
            ......:..|.:.  ...|..|.|.|.  .:..|           |.|..|....|.|....:..
Human   359 VYGAPGFSKDNNSIITRKEFQEGLKIFFPGVSEFGKESILFHYTDWVDDQRPENYREALGDVVGD 423

  Fly   444 YLY---------RF-DMDSPHFNHYRILKCGK----KVRGVCHADDISYMFYGILSSKLDKNSPE 494
            |.:         :| :..:..|.:|...:..|    :..||.|..:|.::| |:...:.|..:..
Human   424 YNFICPALEFTKKFSEWGNNAFFYYFEHRSSKLPWPEWMGVMHGYEIEFVF-GLPLERRDNYTKA 487

  Fly   495 YRTIER-LVGMWTSFATTGDPNCEIIAPVKWDPLRPGGVENCLNI-ADGLEFIPLPESKQFVVWD 557
            ...:.| :|..|.:||..|:||........| |:.....:..|.: .:....:....::|...|.
Human   488 EEILSRSIVKRWANFAKYGNPNETQNNSTSW-PVFKSTEQKYLTLNTESTRIMTKLRAQQCRFWT 551

  Fly   558 SFYTR 562
            ||:.:
Human   552 SFFPK 556

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.