DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gas and Est-Q

DIOPT Version :9

Sequence 1:	NP_611678.1	Gene:	gas / 37572	FlyBaseID:	FBgn0034736	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_649321.1	Gene:	Est-Q / 40381	FlyBaseID:	FBgn0037090	Length:	559	Species:	Drosophila melanogaster

Alignment Length:	541	Identity:	160/541 - (29%)
Similarity:	255/541 - (47%)	Gaps:	89/541 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    32 TKELATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDC-TYAREK 95
            |.||....|.:.|....|.:....:..|.|||||:||:.|||||.|...|.|.|..:. .:.:..
  Fly    43 TVELYNGQGTVLGNYAYTAWTDRAFMQFRGIPFAEPPIEELRFRPPVARSPWTGTLNALNFGQRC 107

  Fly    96 PMQRNSITNAAEGS-EDCLYLNVYAKRLESPKPLPVMVWIFGGGFQVGGASRELYGPDYFMKHDI 159
            |:..|..:..::.. ||||.|:||.|.|.:.:  |||.:|:||||..|  |.|.:.|:|.::.|:
  Fly   108 PVITNLDSQMSDAELEDCLTLSVYTKNLSASQ--PVMFYIYGGGFYNG--SSEDHPPNYLLEKDV 168

  Fly   160 LLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAG-GA 223
            :||...||||.||:||...:||  ||||.:.|.:.||.||:.:|:||.|||:.:|:||:||| |.
  Fly   169 VLVVPQYRVGALGWLSTYTEEL--PGNAPIADILMALDWVQMHISSFGGDPQKVTIFGQSAGAGV 231

  Fly   224 STHILMQTEQARGLFHRAIVQSGSALCAWATQPDRK-WPQRLGKELGYAGNLESEKELLEFFQQI 287
            ::.:|:..:....:|.||||||||...:||...|.| ..:|:..:||.:| .|...:|::..|:
  Fly   232 ASSLLLSPKTGDNMFKRAIVQSGSIFASWAINKDPKAQSRRICIQLGCSG-CEQHDQLVKCIQK- 294

  Fly   288 PASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIGGTSF 352
              :|:.....:..::         :|:|:    |||...|...|..:|..::...||::.|.|..
  Fly   295 --AKVIDILKATASE---------SFSPI----VGDLHGILPQQPSELVKSYRRQIPILTGFTQH 344

  Fly   353 EGLFSYRTTLDDPLYMLSAFEAIIPKQVRDAI-----DKEELAEMV--RRLKK------------ 398
            :|.|...:..|.....::...::..:|....|     |...|.:.:  |.|.|
  Fly   345 DGSFVLASYYDALAAKVANVSSLSVRQFSQGINDLVNDTSGLTDNILNRLLFKPQALNSHDHSAA 409

  Fly   399 --SYFDDPDRASMELYECLHILSIKNFWHDIHRTLLARL-AYATNLPTYLYRFDMDSPHF----- 455
              ||||               |:...|......||..:: ....:.|.|:|.|:.:..:.
  Fly   410 VSSYFD---------------LTTNIFMKSPVITLATKMYTQQRSTPVYVYSFEYEGTYTRFGYE 459

  Fly   456 ---NHYRILKCGKKVRGVCHADDISYMFYGILSSKLDKNSPEYRTIERLVGMWTSFATTGDPNCE 517
               :||..      ..||.|::|..|:|   .:..|:  ..:.:..:::|.:|||||..|.|  .
  Fly   460 FGNSHYPF------NGGVHHSNDNIYLF---ATHPLE--GQDTQMSQKMVDVWTSFAIEGVP--R 511

  Fly   518 IIAPVKWDPLRPGGVENCLNI 538
            .::|:.    ...|..|.||:
  Fly   512 NLSPLS----SASGPYNKLNL 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	157/535 (29%)
gas	NP_611678.1	Aes	<117..>222	CDD:223730	51/105 (49%)
Est-Q	NP_649321.1	COesterase	39..544	CDD:278561	160/541 (30%)
Est-Q	NP_649321.1	Aes	<137..>240	CDD:223730	49/108 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	9	8.970