DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gas and CG3841

DIOPT Version :9

Sequence 1:	NP_611678.1	Gene:	gas / 37572	FlyBaseID:	FBgn0034736	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001188759.1	Gene:	CG3841 / 34278	FlyBaseID:	FBgn0032131	Length:	564	Species:	Drosophila melanogaster

Alignment Length:	596	Identity:	164/596 - (27%)
Similarity:	256/596 - (42%)	Gaps:	130/596 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 IIGHKVVQYKLGTGQTKELATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPS 81
            :||.......:|.....||:  .|:::|...:: :..:..|:|.||.:||.|||:|||..|.|.:
  Fly    15 LIGFTTAVTFIGDDPVVELS--LGRIQGDTMQS-FGNKTIYAFRGIRYAQSPVGQLRFANPVPET 76

  Fly    82 SWQGVRDCTYAREKPMQRNSITNAAEG-------------SEDCLYLNVYAKRLESPKPLPVMVW 133
            ||               .:.:.||...             |||||.:||:.|..|.  ..||||:
  Fly    77 SW---------------GDEVFNATSDSLVCPQPGVVSLMSEDCLKINVFTKSFED--KFPVMVY 124

  Fly   134 IFGGGFQVG-GASRELYGPDYFMKHDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALR 197
            |.||...:| |.|....||.|.:..|::.|..|||:|.|||||....|.|  ||.|..||:.||.
  Fly   125 IHGGANVLGSGHSSYEAGPQYLLDQDVVFVAFNYRLGALGFLSTNSSETK--GNFGFLDQVMALE 187

  Fly   198 WVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWPQ 262
            ||:::|:.|.||||.:|:.|.|||..:..:.:.:..:.|||||||:.||||...:... :..|.:
  Fly   188 WVRDHISHFGGDPELVTIIGISAGSMAVSLHLASPLSAGLFHRAILMSGSATNHFDID-NLFWTR 251

  Fly   263 RLGKELGYAGNLESEKELLEFFQQIPASKLAQYCNSIVTQE---EQRDYEILAFAPVIEPYVGDD 324
            :|.:|||..  :....:::|..:....:::.:.|.:..|.:   .:.:|||            |.
  Fly   252 KLARELGCP--MYDPTDVVECLRNETWTRIVEVCKAWETYQLVNMKWNYEI------------DG 302

  Fly   325 CVIPKSQQEQLSSAWGNSIPMIIGGTSFEGLFSYRTTLD-DPLYMLSAFEAIIPKQVRDAIDKEE 388
            ..:.....|.:.....|.:|::|..|:.|  |.|...:. :..::|..|.:.......:......
  Fly   303 HFLHNHPTELIKEGNFNKVPLLISFTANE--FDYNANVHLENQHLLHDFASNFVDYAPELFLYRH 365

  Fly   389 LAEMVRRLKKSYF-DDPDRASMELYECLHILSIKNF---------WHDIHRTLLARLAYATNLPT 443
            .|::..:||..|. |:....:.|        :|:||         .|.:||  |.:|| :...|.
  Fly   366 DAQIGEKLKDFYLGDNTTEINSE--------NIENFGQIFSDAYIGHGVHR--LVQLA-SHFTPV 419

  Fly   444 YLYRFD------MDSPHFNHYRILKCGKKVRGVCHADDISYM----FYGILSSKLDKNSPEYRTI 498
            |..|.|      :.:|       |....|..||.||||:.|:    :||.|   :..|..:...:
  Fly   420 YYTRMDYVGDQSLSAP-------LNGENKPVGVGHADDLHYVLPGYWYGPL---MAANDSDVFMM 474

  Fly   499 ERLVGMWTSFATTGDP--NCEIIAPVKWDPLR------------PGGVENCLNIADGLEFIPLPE 549
            |||...:|.||.||.|  :.:|..|.....|:            ||                  .
  Fly   475 ERLTSWFTHFAKTGTPLNSTDIWPPCNSTVLKMLYNGVVTQVGSPG------------------Y 521

  Fly   550 SKQFVVWDSFY 560
            |.::.|||..:
  Fly   522 SNRYAVWDKLF 532

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	158/557 (28%)
gas	NP_611678.1	Aes	<117..>222	CDD:223730	48/105 (46%)
CG3841	NP_001188759.1	COesterase	27..528	CDD:278561	158/578 (27%)
CG3841	NP_001188759.1	Aes	<116..>235	CDD:223730	54/122 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467393
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	9	8.890