DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gas and Glt

DIOPT Version :9

Sequence 1:	NP_611678.1	Gene:	gas / 37572	FlyBaseID:	FBgn0034736	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001245946.1	Gene:	Glt / 34193	FlyBaseID:	FBgn0001114	Length:	1026	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	149/525 - (28%)
Similarity:	225/525 - (42%)	Gaps:	87/525 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    36 ATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQG-----VRDCTYAREK 95
            |.:.||:.|..........|..:|.||.:.....|..||:|.| |..:||     |:....|:..
  Fly    64 APEVGQILGISGHKTIANRPVNAFLGIRYGTVGGGLARFQAAQ-PIGYQGRVNATVQSPNCAQFP 127

  Fly    96 PMQRNSITNA-AEGSEDCLYLNVYAKRLESPKPLPVMVWIFGGGFQVGGASRELYGPDYFMKHDI 159
            .:.|..::.: .|..:|||.|::||.  |....|||:|::.|.....||:  |...|||.::.|:
  Fly   128 ELDRLRLSESRGENVDDCLTLDIYAP--EGANQLPVLVFVHGEMLFDGGS--EEAQPDYVLEKDV 188

  Fly   160 LLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAGGAS 224
            |||:||||:...||||....||  |||..|.|...||.|::.|:..|.|:...:|:.|::.|...
  Fly   189 LLVSINYRLAPFGFLSALTDEL--PGNVALSDLQLALEWLQRNVVHFGGNAGQVTLVGQAGGATL 251

  Fly   225 THILMQTEQARGLFHRAIVQSGSALCAWA--TQP----------DRKWPQRLGKELGYAGNLESE 277
            .|.|..:.:|..||.:.|:|||:||..:.  .||          .|..|..:..      :.:..
  Fly   252 AHALSLSGRAGNLFQQLILQSGTALNPYLIDNQPLDTLSTFARLARCPPPSINP------SAQGL 310

  Fly   278 KELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNS 342
            |.|.:...::|.|:|......::.|.|......|....::   |||......|....|::....:
  Fly   311 KPLYDCLARLPTSQLVAAFEQLLLQNEHLGLTQLGGFKLV---VGDPLGFLPSHPASLATNSSLA 372

  Fly   343 IPMIIGGTSFEGLFSYRTTLDDPLYMLSAFEAIIPKQVRDAID---KEELAEMVRRLKKSYFDDP 404
            :|||||.|.....|.. :.:.|.|..|.:      :.|.|.||   :........||.|.:
  Fly   373 LPMIIGATKDASAFIV-SRIYDQLARLQS------RNVSDYIDVVLRHTAPPSEHRLWKQW---- 426

  Fly   405 DRASMELYECLH------------ILSIKNFWHDIHRTLLARLAYATNL-------PTYLYRFDM 450
              |..|::..:.            :|.:.|:       :|.|.....::       |.|||.||.
  Fly   427 --ALREIFTPIQEQTASLQTVAPGLLELSNY-------ILYRAPVINSISQSYRSVPAYLYTFDY 482

  Fly   451 DSPH--FNHY-RILKCGKKVRGVCHADDISYMF-YGILSSKLDKNSPEYRTIER-LVGMWTSFAT 510
            ...|  |.|. ..|..|.   ....:||..|:| |...:|:|   :|..|::.| ||.||.:|||
  Fly   483 RGEHHRFGHLSNPLPFGV---DASLSDDSVYLFPYPPEASRL---NPLDRSLSRALVTMWVNFAT 541

  Fly   511 TGDPN 515
            ||.||
  Fly   542 TGVPN 546

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	149/525 (28%)
gas	NP_611678.1	Aes	<117..>222	CDD:223730	41/104 (39%)
Glt	NP_001245946.1	COesterase	55..579	CDD:278561	149/525 (28%)
		Aes	<146..345	CDD:223730	66/210 (31%)
		RILP-like	<677..>717	CDD:304877
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45467428
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR43142
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.950