DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gas and CG6414

DIOPT Version :9

Sequence 1:	NP_611678.1	Gene:	gas / 37572	FlyBaseID:	FBgn0034736	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001303565.1	Gene:	CG6414 / 31352	FlyBaseID:	FBgn0029690	Length:	583	Species:	Drosophila melanogaster

Alignment Length:	516	Identity:	189/516 - (36%)
Similarity:	273/516 - (52%)	Gaps:	54/516 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 TLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQG----VRDCTYAREK-PMQRNSITNAAEG 108
            |.::|....:|.|:|:|:||:.:||||.|.|.:.|:|    ::|.....:: |.:|:.|   .||
  Fly    46 TTHNGRHMRAFMGVPYAEPPLDDLRFRPPVPKAPWEGERLAIKDAPICLQRDPFRRDMI---LEG 107

  Fly   109 SEDCLYLNVYAKRLESPK---PLPVMVWIFGGGFQVGGASRELYGPDYFMKHDILLVTINYRVGV 170
            ||||||||||..  |.|:   .||||||..|||:|.|......||||:.:.|||:||:.|:|:|.
  Fly   108 SEDCLYLNVYTP--ERPRTNGSLPVMVWFHGGGWQCGSGISSFYGPDFLLDHDIVLVSANFRLGP 170

  Fly   171 LGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAGGASTHILMQTEQAR 235
            |||||  .:.|..|||.|||||::.|.||:.|||||.|||.|:|||||||||||....|.:|::|
  Fly   171 LGFLS--TETLDCPGNNGLKDQLEVLHWVRANIASFGGDPNSVTVFGESAGGASVTYHMLSEKSR 233

  Fly   236 GLFHRAIVQSGSALCAWATQPDRKW-----PQRLGKELGYAGNLESEKELLEFFQQIPASKL-AQ 294
            ||.||.|.|||:....|| ||..|.     ..:|.:.:| .||.....|.||..::.||..: |.
  Fly   234 GLLHRGIAQSGTYFNPWA-QPAHKGVAAGRATKLAQIVG-CGNAGEWPEKLECLRKKPAEDIVAS 296

  Fly   295 YCNSIVTQEEQRDYE-ILAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIGGTSFEGLFSY 358
            ..:..|.     |:: ::.|.||:||  ..|.........|.:...|..:|:::|.|:.|||...
  Fly   297 LYDMFVW-----DFDPMIPFPPVVEP--EHDGAFLTVAPRQAAKPHGLQLPLMVGATAEEGLLKT 354

  Fly   359 RTTLDDPLYML---SAFEAIIPKQVR-DAIDKEELAEMVRRLKKSYF---DDPDRASMELYECLH 416
            ...|:.|..:.   |.||.::|..:. |..|......:.:|::..||   .|.|:|:.:  ....
  Fly   355 AALLNLPQLLAEFKSQFEQVLPVVLNYDHHDDSVRQTITQRIESFYFKSGHDYDKANHQ--NLTD 417

  Fly   417 ILSIKNFWHDIHRTLLARLAYATNLPTYLYRFD-MDSPHFNHYRILKCGK-KVRGVCHADDISYM 479
            ::|...|...|...|..|::.....|||:|.|| ..:..|.  .|.|.|: :..|.|||:::.|:
  Fly   418 LISDGWFVAGIDEYLRLRMSQEDVAPTYVYLFDHKGAASFT--EIFKGGRNEFYGACHAEELQYL 480

  Fly   480 F-YG---ILSSKLDKNSPEYRTIERLVGMWTSFATTGDPNCEIIA---PVKWDPLRPGGVE 533
            | .|   .:|:...:...|.|  |.::.:|.|||.||:||...::   | .|.|.....||
  Fly   481 FPIGRELFVSAVPTQKDLELR--ELMLHLWVSFAKTGNPNPTNVSFHLP-NWSPASSYPVE 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	189/516 (37%)
gas	NP_611678.1	Aes	<117..>222	CDD:223730	60/107 (56%)
CG6414	NP_001303565.1	COesterase	36..567	CDD:278561	189/516 (37%)
CG6414	NP_001303565.1	Aes	<116..>254	CDD:223730	78/142 (55%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	98	1.000	Domainoid score	I1867
eggNOG	1	0.900	-	-		E2759_KOG1516
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	99	1.000	Inparanoid score	I1664
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm46967
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
	8	7.760