Protein Alignment gas and Nlgn3

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_766520.2
• Gene: Nlgn3 / 245537
• MGIID: 2444609
• Length: 825
• Species: Mus musculus
• Alignment Length: 630
• Identity: 185/630 - (29%)
• Similarity: 263/630 - (41%)
• Gaps: 192/630 - (30%)

  Fly    37 TKYGQLKGQQRRTLYDGE---PYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCTYAREKPMQ 98
            |.:|:|:|  .|.....|   |...:.|:|:|.||:||.||..|:||.||.|:|:.|:.  .|:.
Mouse    43 THFGKLRG--ARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHF--PPVC 103

  Fly    99 RNSITNAA---------------------EGSEDCLYLNVY--------AKR------------- 121
            ..:|..|.                     |.:|||||||||        ||:
Mouse   104 PQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDGSGAKKQGEDLADNDGDED 168

  Fly   122 --LESPKPLPVMVWIFGGGFQVG------GASRELYGPDYFMKHDILLVTINYRVGVLGFLSLKD 178
              :......||||:|.||.:..|      |:....||       :::::|:|||||||||||..|
Mouse   169 EDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYG-------NVIVITLNYRVGVLGFLSTGD 226

  Fly   179 KELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIV 243
            :..|  ||.||.|||||||||.||||.|.|||..|||||...|.:...:|..:..:.|||.|||:
Mouse   227 QAAK--GNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGASCVSLLTLSHHSEGLFQRAII 289

  Fly   244 QSGSALCAWAT--QPDRKWPQRLGKELGYAGNLESEKELLEFFQQIPASKLAQYCNSIVTQEEQR 306
            ||||||.:||.  || .|:...|..::|.  |:....::::..:|..|.:|       |.|:.|.
Mouse   290 QSGSALSSWAVNYQP-VKYTSLLADKVGC--NVLDTVDMVDCLRQKSAKEL-------VEQDIQP 344

  Fly   307 DYEILAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIGGTSFEGLFSYRTTLD-------- 363
            ....:||.|||:   ||  |||...:..:......:..:::|....|||......:|
Mouse   345 ARYHVAFGPVID---GD--VIPDDPEILMEQGEFLNYDIMLGVNQGEGLKFVEGVVDPEDGVSGT 404

  Fly   364 DPLYMLSAFEAIIPKQVRDAID--------KEELAEMVRRLKKSYFDDPDRASMEL-YECLHILS 419
            |..|.:|.|           :|        |:.|.|.:   |..|.|..||.:.|. .:.|..|.
Mouse   405 DFDYSVSNF-----------VDNLYGYPEGKDTLRETI---KFMYTDWADRDNPETRRKTLVALF 455

  Fly   420 IKNFW-------HDIHRTLLARLAYATNLPTYLYRFDMDSPHFNHYRILKCGKKVR----GVCHA 473
            ..:.|       .|:|    ||  |.:  |||.|.|      ::|     |...::    ...|.
Mouse   456 TDHQWVEPSVVTADLH----AR--YGS--PTYFYAF------YHH-----CQSLMKPAWSDAAHG 501

  Fly   474 DDISYMF-------YGILSSKLDKNSPEYRTIERLVGMWTSFATTGDPNCEIIAPVKWDPLRPGG 531
            |::.|:|       ..:......||......:  ::..||:||.|||||
Mouse   502 DEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAV--VMTYWTNFAKTGDPN---------------- 548

  Fly   532 VENCLNIADGLEFIPLPESKQF----------VVWDSFYTRESLY 566
                         .|:|:..:|          |.|..:..|:.||
Mouse   549 -------------KPVPQDTKFIHTKANRFEEVAWSKYNPRDQLY 580

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	177/586 (30%)
		Aes	<117..>222	CDD:223730	55/133 (41%)
Nlgn3	NP_766520.2	COesterase	39..601	CDD:365897	185/630 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	151..172		2/20 (10%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	622..668

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832439
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740