Protein Alignment gas and Ces4a

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_666325.2
• Gene: Ces4a / 234677
• MGIID: 2384581
• Length: 563
• Species: Mus musculus
• Alignment Length: 557
• Identity: 182/557 - (32%)
• Similarity: 258/557 - (46%)
• Gaps: 101/557 - (18%)

  Fly    13 LGAKIIGHKVVQYKLGTGQTKE--LATKYGQLKGQQRRTLYDGE-PYYSFEGIPFAQPPVGELRF 74
            ||..:....|||..||...|||  |.||:|.|:|:|   ::.|: |...|.||||::||||..||
Mouse    12 LGLSLTLCLVVQTALGALHTKEPLLITKHGILQGKQ---VHVGDTPIQVFLGIPFSKPPVGTRRF 73

  Fly    75 RAPQPPSSWQGVRDCTYAREKPMQR------NSITNAAEG------SEDCLYLNVYAKRLESPKP 127
            ..|:||..|.|:||.|......:|.      :...|..:.      |||||||||||..|....|
Mouse    74 APPEPPLPWNGIRDATTYPPSCLQESWGQILSMYLNTRKQYKWLHFSEDCLYLNVYAPVLAPGAP 138

  Fly   128 -LPVMVWIFGGGFQVGGASRELYGPDYFMKHDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKD 191
             ||||||..||.|..|.|| ...|.:...:..::||.:.||:|:|||.|..:...:  ||.||.|
Mouse   139 LLPVMVWFPGGAFLAGSAS-TYEGSELAARGKVVLVFLQYRLGILGFFSTGNSHAR--GNWGLLD 200

  Fly   192 QIQALRWVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWATQP 256
            ||.|||||:|||.:|.|||:|:|:||:|||..|...||.:..|:||||:||.|||:|:......|
Mouse   201 QIAALRWVQENIEAFGGDPDSVTLFGQSAGAMSVSGLMVSPLAQGLFHQAISQSGTAVLKAFITP 265

  Fly   257 DRKWPQRLGKELGYAGNLE--SEKELLEFFQQIPASK--LAQYCNSIVTQEEQRD-YEILAF-AP 315
            |   |....|::.:....:  |.|.::|..:.:.|.:  |.....|.......:| .||:.| :|
Mouse   266 D---PLTSAKKIAHLAGCDHNSTKVMVECLRSLSAEEVTLVSKRMSFFQANSHKDPKEIVWFLSP 327

  Fly   316 VIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIG--GTSFEGLFSY------------RTTLDDPL 366
            |:     |..|.|:.....|:......:|.::|  ...||....:            :|.::..|
Mouse   328 VV-----DGVVFPEDPVVLLTRGQVKPVPYLLGVNNAEFEWNLPFLMKIQLNQRMMNQTNINKIL 387

  Fly   367 YMLSAFEAIIPKQVRDAIDKEELAEMVRRLKKSYFDDPDRASMELYECLHILSIKNF-WHDIHRT 430
            :   :|..::      .|.||::..:.|    .|.:|               :|.|. |......
Mouse   388 W---SFNVLL------NITKEQVPVVAR----EYLND---------------AISNHDWKMFRNR 424

  Fly   431 LL-----ARLAYAT----------NLPTYLYRFDMDSPHFNHYRILKCGKKVRGVCHADDISYMF 480
            |:     |...|||          ..|.|||.|   ..|.:...|:   |...|..|.|::||:|
Mouse   425 LIDLIGDATFVYATLQAARYHRDAGSPVYLYEF---KHHASSGIII---KPYNGADHGDELSYLF 483

  Fly   481 YGILSSKLDKNSPEYRTIERLVGMWTSFATTGDPNCE 517
             |...||......|.....:::..|.:||.||:||.|
Mouse   484 -GSPFSKGSSAGEEKEFSLQMMKYWANFAHTGNPNGE 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	176/542 (32%)
		Aes	<117..>222	CDD:223730	52/105 (50%)
Ces4a	NP_666325.2	COesterase	30..554	CDD:278561	175/539 (32%)
		Aes	<128..>272	CDD:223730	70/149 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832836
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650