Protein Alignment gas and Nlgn1

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_006535478.1
• Gene: Nlgn1 / 192167
• MGIID: 2179435
• Length: 863
• Species: Mus musculus
• Alignment Length: 651
• Identity: 184/651 - (28%)
• Similarity: 264/651 - (40%)
• Gaps: 199/651 - (30%)

  Fly    35 LATKYGQLKGQQRRTLYDGE---PYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCT-YAREK 95
            :.|.:|:::|.::.  .:.|   |...|.|:|:|.||.||.||:.|:|||.|..:|:.| :|...
Mouse    55 VTTNFGKIRGIKKE--LNNEILGPVIQFLGVPYAAPPTGEHRFQPPEPPSPWSDIRNATQFAPVC 117

  Fly    96 PMQRNSI-------------TN--------AAEGSEDCLYLNVY-----AKRL------------ 122
            |  :|.|             ||        ..:.||||||||:|     .||:
Mouse   118 P--QNIIDGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKI 180

  Fly   123 ---------------------------ESPKPLPVMVWIFGGGFQVG------GASRELYGPDYF 154
                                       :|..|.||||:|.||.:..|      |:....||
Mouse   181 CRKGGPLTKKHTDDLGDNDGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNLYDGSVLASYG---- 241

  Fly   155 MKHDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGES 219
               :::::|:|||:|||||||..|:..|  ||.||.|.||||||..|||..|.|||..|||||..
Mouse   242 ---NVIVITVNYRLGVLGFLSTGDQAAK--GNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSG 301

  Fly   220 AGGASTHIL---------MQTEQARGLFHRAIVQSGSALCAWAT--QPDRKWPQRLGKELGYAGN 273
            |||:..::|         ..:...:|||.|||.|||:||.:||.  || .|:.:.|..::|.  |
Mouse   302 AGGSCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQP-AKYARILATKVGC--N 363

  Fly   274 LESEKELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPKSQQEQLSSA 338
            :....||:|..|:.|..:|       |.|:.|.....:||.|||:   ||  |||...|..:...
Mouse   364 VSDTVELVECLQKKPYKEL-------VDQDVQPARYHIAFGPVID---GD--VIPDDPQILMEQG 416

  Fly   339 WGNSIPMIIGGTSFEGLFSYRTTLD-DPLYMLSAFEAIIPKQVRDAIDKEELAEMVRRLKKSYFD 402
            ...:..:::|....|||......:| |.....|.|:..:...|.:.....|..:::|...|..:.
Mouse   417 EFLNYDIMLGVNQGEGLKFVENIVDSDDGVSASDFDFAVSNFVDNLYGYPEGKDVLRETIKFMYT 481

  Fly   403 DPDRASMELYECLHILSIKNFWHDIH------RTLLARL--------AYAT-------NLPTYLY 446
            |                    |.|.|      :||||..        |.||       ..|||.|
Mouse   482 D--------------------WADRHNPETRRKTLLALFTDHQWVAPAVATADLHSNFGSPTYFY 526

  Fly   447 RFDMDSPHFNHYRILKCGKKV---RGVCHADDISYMFYGI--------LSSKLDKNSPEYRTIER 500
            .|      ::|.:.    .:|   ....|.|::.|:. ||        ......||......:
Mouse   527 AF------YHHCQT----DQVPAWADAAHGDEVPYVL-GIPMIGPTELFPCNFSKNDVMLSAV-- 578

  Fly   501 LVGMWTSFATTGDPNCEIIAPVKWDPLRPGGVENCLNIADGLEFIPLPESKQFVVWDSFYTRESL 565
            ::..||:||.|||||..:....|:...:|...|.                   |.|..:..::.|
Mouse   579 VMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEE-------------------VAWTRYSQKDQL 624

  Fly   566 Y 566
            |
Mouse   625 Y 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	179/617 (29%)
		Aes	<117..>222	CDD:223730	53/154 (34%)
Nlgn1	XP_006535478.1	COesterase	53..646	CDD:365897	184/651 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167832524
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740