Protein Alignment gas and cest-3

DIOPT Version :10

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_510042.2
• Gene: cest-3 / 181385
• WormBaseID: WBGene00008451
• Length: 588
• Species: Caenorhabditis elegans
• Alignment Length: 556
• Identity: 134/556 - (24%)
• Similarity: 222/556 - (39%)
• Gaps: 163/556 - (29%)

  Fly    28 GTGQTKELATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCTYA 92
            |:|| :.::|.||:|:|:....     ..:.|:.:|||:||:|:|||..|:..:.|:.:|:.|..
 Worm    18 GSGQ-RIISTTYGKLEGKTVNV-----DQHMFKNVPFAKPPLGKLRFSLPEWTNPWKNIRNATEY 76

  Fly    93 REKPMQRNSI---TNAAEGSEDCLYLNVYAKR--LESPKPLPVMVWIFGGGFQVGGASR--ELYG 150
            .......:|:   :|....|||||||||:...  |:| |....:|:..|||..:..|.:  :.:.
 Worm    77 SPSCFSNSSMRTDSNFFPMSEDCLYLNVFTNEYCLKS-KNCSTVVYYHGGGINMDSAVQFNDTFI 140

  Fly   151 PDYFMKHDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITV 215
            .:.::|.:::.:...||:|:.|.|......| :|.|..:.|...|||::.:.|::|.|..:.|.:
 Worm   141 LERYVKENVVFIIPAYRLGIFGLLYFGSNNL-VPQNLAIHDCELALRFIHQEISNFGGHKDDINL 204

  Fly   216 FGESAG-------GASTHILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWPQRLGKELGYAGN 273
            .|.|||       |.|.||    :....|.:|.||.|        ..|....|:.|
 Worm   205 MGHSAGAHISLIFGFSRHI----DPDHKLINRIIVLS--------PVPSYDMPELL--------- 248

  Fly   274 LESEKELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPKSQQEQLSSA 338
               .|...:|     |.::..|..::..    ||.||:            .|:..|..:
 Worm   249 ---IKNCYDF-----AERVGCYKRNVTA----RDTEIV------------KCLRKKDAR------ 283

  Fly   339 WGNSIPMIIGGTSFEGLFSYRTTLD-DPLYMLSAFEAIIPKQVRD--AIDKEELA---EMV---- 393
                           ||.|.:..:: |.||..: |.|..|...||  ..|.:|.|   :|:
 Worm   284 ---------------GLMSMQRLMENDRLYFWN-FLAGEPFMYRDESIADFKEYAVKRDMLIGNT 332

  Fly   394 ------RRLKK-------SYFD--DPDRASMELYECLHILSIKNFWHD---IHRT--------LL 432
                  :||||       |:.|  :|       ||..|..   ||:||   ::.|        .:
 Worm   333 VDEVKWKRLKKENPAIAGSFMDWENP-------YEVAHKF---NFYHDSAPVNSTYESFTQGIFV 387

  Fly   433 ARLAYA---TNLPTYLYRFDMDSPHFNHYRILKCGKKVRGVCHADDISYMFYGILSSKLDKNSPE 494
            :...||   .|....:|.|..:....:|                  :|.|.|.:.:.:.|.::.:
 Worm   388 STATYAEAQANAGGTVYLFQSNQQPSSH------------------VSDMQYFVGTHREDYHTSD 434

  Fly   495 YRTIERLVG-MWTSFATTGDPNCEIIAPVKWDPLRP 529
            ...::.... |..:|...|.|     :|| |:||.|
 Worm   435 MDIMDTFYSKMIVNFTKFGSP-----SPV-WEPLVP 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	31..529	CDD:395084	131/551 (24%)
cest-3	NP_510042.2	alpha/beta hydrolases	21..496	CDD:473884	132/553 (24%)