Protein Alignment gas and cest-16

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_741812.2
• Gene: cest-16 / 180905
• WormBaseID: WBGene00020330
• Length: 697
• Species: Caenorhabditis elegans
• Alignment Length: 608
• Identity: 159/608 - (26%)
• Similarity: 248/608 - (40%)
• Gaps: 160/608 - (26%)

  Fly    25 YKLGTGQTKELATKYGQLKGQQRRTLY--DGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVR 87
            :....||..|.:......:|..|..:|  ||:....|.|:|:|:||:|||||:.|...:.|.
 Worm    12 FSWANGQLLEKSRSVWVEQGLVRGNIYNIDGKHIQIFRGVPYAEPPIGELRFKPPVKKTRWH--- 73

  Fly    88 DCTYAREKP-------------MQRN---SITNAAEGSEDCLYLNVYAKRLESP-------KPLP 129
                 :|.|             ..:|   :.||....|||||||||:     ||       |..|
 Worm    74 -----QELPAVEYGPPCLQFMDFHKNDKFAKTNMDRQSEDCLYLNVF-----SPYDTDDESKTYP 128

  Fly   130 VMVWIFGGGFQVG----GASRELYGPDYFMKHDILLVTINYRVGVLGFLSLKDKELKIPGNAGLK 190
            ::|||.||.|..|    |...|:...:...| .|..|:||||:|.|||::.::.: |:.||.|:.
 Worm   129 ILVWIHGGSFLAGSADTGIDMEVIAANIVSK-GIAFVSINYRLGPLGFMNYQNGD-KLEGNFGIW 191

  Fly   191 DQIQALRWVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWA-- 253
            |.:.||:|::.||..|||||..:||.|||||||::.:|..:.:..||.|:||:.|||::..||
 Worm   192 DMVMALQWIQSNIKQFNGDPTKVTVMGESAGGAASSLLALSPKTSGLLHQAIIMSGSSMAGWAIH 256

  Fly   254 --TQPD------------RKWPQRLGKELGYAGNLESEKELL-EFFQQIP----ASKLAQYCN-- 297
              :||.            .||.           |.:..||:: :.:|.:.    .|.|..|.|
 Worm   257 RHSQPAYSVDNLVAYFRCEKWI-----------NEDDTKEVVGDEYQHLTHSVIRSALCNYQNVK 310

  Fly   298 -----SIVTQEEQRD---YEILAFAPV----------IEPYVGDDCVIPKSQQEQLSS------- 337
                 ..:||.::.:   .|:...:|:          :...|.|..::|.|....:.:
 Worm   311 INCLTDDMTQMDKMNCLRKELNFSSPLFRKALAAELGVSKMVVDGDLVPSSGVSLVRNNARIPIM 375

  Fly   338 ------AWGNSIPMIIGGTSFEGLFSYRTTLDDPLYML---SAFEAIIPKQVRDAIDKEELAEMV 393
                  .||:...|.......:||  .|:.:::.:|.:   |..|....|.....:.....|.:|
 Worm   376 TGVARKEWGHKKAMFYNMHQRDGL--KRSDVEEQVYRIIDNSFHETASEKLANSTVQLIANATIV 438

  Fly   394 RRLKKSYFDDPDRASMELYECLHILSIKNFWHDIHRTLLARLAYAT----NLPTYLYRFDM--DS 452
            |     |.:.|:.   |......:.:::....||..........|.    .:|.|||.||.  .|
 Worm   439 R-----YLETPNN---EFIADQVVGALQKLESDIEFVAPCEREVAAYVDKGVPVYLYSFDYVPKS 495

  Fly   453 PHFNHYRILKCGKKV---------------------RGVCHADDISYMFYGILSSKLDKNSPEYR 496
            |      ||:..:|:                     :...|..|.:::|....||..: .||..:
 Worm   496 P------ILESERKIYSLFGTKPVEMKRTEKSEILEKAAFHGLDHAFIFSKGYSSNFE-ISPYTK 553

  Fly   497 TIER----LVGMWTSFATTGDPN 515
            ..|.    |..|.|:|...|||:
 Worm   554 REETMSKILCTMLTNFVKNGDPS 576

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	159/605 (26%)
		Aes	<117..>222	CDD:223730	46/115 (40%)
cest-16	NP_741812.2	Abhydrolase	25..608	CDD:389770	156/595 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810