Protein Alignment gas and cest-2.2

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_001256567.1
• Gene: cest-2.2 / 179917
• WormBaseID: WBGene00013874
• Length: 672
• Species: Caenorhabditis elegans
• Alignment Length: 562
• Identity: 147/562 - (26%)
• Similarity: 228/562 - (40%)
• Gaps: 141/562 - (25%)

  Fly     8 SDKLKLGAKIIGHKVVQYKLGTGQTKELATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGEL 72
            |.|:||.:          :.||.:.:.|...|..| |.|...:        |.|:|:.:||||.|
 Worm    17 STKVKLSS----------RTGTIEGRTLTASYSPL-GNQTGIV--------FFGVPYVEPPVGNL 62

  Fly    73 RFRAPQPPSSWQGVRDCTYAREKPM--QRNSITNAAEG--SEDCLYLNVYAKR--LESPKPLPVM 131
            |||.|:||..|.||.:....:...|  |:.:..|...|  ||||||.||:..:  ||. |...||
 Worm    63 RFRKPRPPKPWDGVLEAKEYKAACMSDQKKTYKNGVGGPVSEDCLYANVFTNQYCLEH-KNCSVM 126

  Fly   132 VWIFGGGFQVGGASRELYGPDYFMKH------DILLVTINYRVGV--LGFLSLKDKELKIPGNAG 188
            :.|.||.|.:..||  .|.|:..:.:      :|::||.|||:|:  ||.|:..:::.    |.|
 Worm   127 LTIHGGRFVIESAS--AYDPEIIINNFVGQGRNIVVVTFNYRLGLFGLGMLNGDNQDT----NFG 185

  Fly   189 LKDQIQALRWVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWA 253
            |.|.::.:||.::.|.:|.||.:.||:.|.|||...|.....:..::||.|:.|:.|.|
 Worm   186 LYDILEVVRWTRKEIKNFGGDKDRITMQGHSAGAVFTAAFSTSPLSKGLIHQQIIMSAS------ 244

  Fly   254 TQPDRKWPQRLGKELGYAGNLESEKELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIE 318
                             ..||..:..:.|         |......:....::..:..|:...|.:
 Worm   245 -----------------MSNLSKKSNVKE---------LTVVARIVGCLPDEHGFPKLSNVEVEK 283

  Fly   319 PYVGDDCVIPKSQQEQLSSAWGNSIPMI------IGGTSFEGLFSYRTTLDDPLYMLSAFEAIIP 377
            .|.   |:..||.|:.|.:    .:.|:      ||....:|:  |:....|.||   |..:|.|
 Worm   284 AYT---CLRSKSAQQILDA----QLYMLRNTTYYIGQGHIDGI--YQVDYPDNLY---ATNSIYP 336

  Fly   378 KQVRDAIDKEELAEMVRRLKKSYFDDP--------------DRASMELYECLHILSIK--NFWH- 425
            ..........||      :...|..||              :....|||:.....|.|  ||:.
 Worm   337 INTMIGTTTAEL------MDSRYIVDPKNTGKKEILLQNLCEHIGYELYKEPEEFSQKCRNFYKN 395

  Fly   426 -DIHRTL------------LARLAYATNLPTYLYRFDMDSPHFNHYRILKCGKKVRGVCHADDIS 477
             :..::|            ||.:..:.:...::|.||..... |.|:  |..|.: ...|.:|.:
 Worm   396 GEDAKSLGDDMEFYYGAIQLANVHSSKDTNVFVYSFDYKEAG-NAYK--KYDKSL-SPKHGEDFA 456

  Fly   478 YMF---YGILSSKLDKNSPEYRTIERLV-GMWTSFATTGDPN 515
            |.|   .|..|:|      :| .||.:. ||:..|...|||:
 Worm   457 YAFGTNRGNFSTK------DY-VIEYIYSGMFADFVNFGDPS 491

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	143/542 (26%)
		Aes	<117..>222	CDD:223730	39/114 (34%)
cest-2.2	NP_001256567.1	Abhydrolase	25..534	CDD:389770	143/544 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157019
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.840