Protein Alignment gas and cest-2.1

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_506508.2
• Gene: cest-2.1 / 179916
• WormBaseID: WBGene00013875
• Length: 675
• Species: Caenorhabditis elegans
• Alignment Length: 618
• Identity: 150/618 - (24%)
• Similarity: 247/618 - (39%)
• Gaps: 160/618 - (25%)

  Fly     3 LRVSFSDKLKLGAKIIGHKVVQYKLGTGQTKELATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQP 67
            |.:|.|.:            ||...||.:.|.|.:.|..|..      :.|   ..|.||||.:|
 Worm    13 LHISISTR------------VQLSTGTIEGKILTSTYSPLGN------HTG---IGFLGIPFVEP 56

  Fly    68 PVGELRFRAPQPPSSWQGVRDCTYAREKPMQ--RNSITNAAEG--SEDCLYLNVYA-----KRLE 123
            |.|.||||.|:||..|.|:.:....:...|.  :.:..|...|  ||||||.||:.     ||
 Worm    57 PAGNLRFRKPRPPIPWDGILETKEYKPACMSDAKKTYKNGVGGPISEDCLYANVFTNQYCMKR-- 119

  Fly   124 SPKPLPVMVWIFGGGFQVGGASRELYGPDYFMKH------DILLVTINYRVGVLGFLSLKDKELK 182
              |...||:.:.||......||  .:.|:..:.:      :|::||.|||:|..||..|..:  |
 Worm   120 --KNCSVMIVVHGGRILTESAS--AFNPEILVNNFVGQGRNIVVVTFNYRLGTFGFGVLNGE--K 178

  Fly   183 IPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGS 247
            ...|.|:.|.::|::|.::.:.:|.|:.:.:|:.|.||||:.......:..::|:.::.|:.||:
 Worm   179 GDSNVGMFDMLEAVKWTRKEVHNFGGNKDKLTMVGHSAGGSLVGAFTSSPLSKGMLNQQIIMSGA 243

  Fly   248 ALCAWATQPDRKWPQRLGKELGYAGNLESEKE---LLEFF-----QQIPASKLAQYCNSIVTQE- 303
            .             .::||...:.|.....::   |.|.|     .|:...|......:|..||
 Worm   244 L-------------YQMGKLANFKGMTAMAQKAGCLPEVFGFRKLSQVRIDKTYSCLRNISAQEV 295

  Fly   304 --------EQRDYEILAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIGGTSFEGLFSYRT 360
                    :...|.|..      |::..:.::..| .|.|:|...:.|..:||.|:.|
 Worm   296 LDAQLWVLQNTTYYISV------PHIDGEFLLNYS-DEILASGTIHPINSMIGTTTAE------- 346

  Fly   361 TLDDPLYMLSAFEAIIPKQVRDAIDKEEL----------------AEMVRRLKKSYFDDPDRA-- 407
             |.||:|:         ..:::|..||||                .|..|:.:|.|.:..|..
 Worm   347 -LRDPIYI---------NDLKNADKKEELLKNLCEHIGYELYTEPEEFSRKCQKFYGNGDDAQFL 401

  Fly   408 --SMELYECLHILSIKNFWHDIHRTLLARLAYATNLPTYLYRFDMD--SPHFNHYRILKCGKKVR 468
              .||.|:.    |||          :|....:.|...::|.:|..  .|.|..|      .:..
 Worm   402 ADDMEFYDG----SIK----------VANAHASKNTKVFMYSYDYKDAGPAFKKY------AQAP 446

  Fly   469 GVCHADDISYMFYGILSSKLDKNSPEYRTIERLV-GMWTSFATTGDPNCEIIAPVKWDPLRPGGV 532
            ...|::|:.|:|.   :|:.:....:| .||::. ||:..|...|:|:..  ...||....|
 Worm   447 PPHHSEDLIYVFG---TSRGNFTEKDY-VIEQIYSGMFADFVNFGNPSPS--KEQKWKEYSP--- 502

  Fly   533 ENCLNIADGLEFIPLPESKQFVV---WDSFYTR 562
                   :..|:..:...|.|.:   .|.:|:|
 Worm   503 -------EKREYFLIDFDKNFTMPGTRDGYYSR 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	139/560 (25%)
		Aes	<117..>222	CDD:223730	33/115 (29%)
cest-2.1	NP_506508.2	COesterase	21..533	CDD:365897	147/598 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157070
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740