Protein Alignment gas and cest-1.2

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_506504.2
• Gene: cest-1.2 / 179914
• WormBaseID: WBGene00011364
• Length: 676
• Species: Caenorhabditis elegans
• Alignment Length: 568
• Identity: 149/568 - (26%)
• Similarity: 229/568 - (40%)
• Gaps: 144/568 - (25%)

  Fly     7 FSDKLKLGAKIIGHKVVQYKLGTGQTKELATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGE 71
            ||.:..:..|      ||...|..:.|:|.:.|.....|..         .:|.|||:.:||:|:
 Worm    11 FSAQFAISTK------VQLSTGIIEGKQLNSTYSPFGNQSA---------IAFLGIPYVEPPIGD 60

  Fly    72 LRFRAPQPPSSWQGVRDCTYAREKPMQRNSIT--NAAEG---SEDCLYLNVYAKR--LESPKPLP 129
            ||||.|:|..:|.||.:....:...|..::.|  |...|   |||||||||...:  ||: |...
 Worm    61 LRFRKPRPQKTWSGVLETKKFKPACMSNSTKTYKNGGIGGPISEDCLYLNVLTNQYCLEN-KNCS 124

  Fly   130 VMVWIFGGGFQVGGAS--------RELYGPDYFMKHDILLVTINYRVGVLGFLSLK----DKELK 182
            |::.:.|||:....|:        ....|.|    .:|::||||||:|:.||..|.    ||
 Worm   125 VVIIVHGGGYLFESAATFNHEILVNNFVGQD----RNIVVVTINYRLGIFGFGHLNGFEGDK--- 182

  Fly   183 IPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGS 247
               |.|:.|.::|::||:..|..|.|:.:.||:.|.|||.........:...:||.|:.||.||.
 Worm   183 ---NVGIFDTLEAVKWVRREIKQFGGNKDRITLAGHSAGAGVVAAFTISPLTKGLIHQQIVMSGP 244

  Fly   248 ALCAWATQPDRK--------WPQRLG---KELGYAGNLESEKELLEFFQQIPASKLAQY--CNSI 299
                 .|...:|        ..:|:|   |:.|              |.::|..::.|.  |...
 Worm   245 -----MTNMSKKSNFKGMTAMAERVGCHSKKYG--------------FNKLPEHEVEQVYSCLRK 290

  Fly   300 VTQEEQRDYEI---------LAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIGGTSFEGL 355
            ...:|..|.::         ....||...::.|   .|.:...:.|..   ||..::|.|:.|
 Worm   291 KPAQELLDAQLWLLQNSTFYFGAPPVDGEFITD---YPDNLYSEKSIF---SINTLLGTTTRE-- 347

  Fly   356 FSYRTTLDDPLYM----LSAFEA--IIPKQVRDAIDKE---ELAEMVRRLKKSYFDDPDRAS--- 408
                  |.|..|:    .|.||.  ...|.:.|.|..|   |..:...:.:|.|.:..|..|
 Worm   348 ------LQDTGYISNSNYSKFETKETFLKNLCDQIGIEIYKESEDFSSKCQKWYINGSDSKSLSD 406

  Fly   409 -MELY-ECLHILSIKNFWHDIHRTLLARLAYATNLPTYLYRFDMDSPHFNHYRILKCGKKVRGVC 471
             ||.| :.:::.       |.|    ||......:  |.|.:....|.|..|      .||:...
 Worm   407 DMEFYTQAINLA-------DAH----ARKGKKVYM--YSYAYSGAGPAFKKY------MKVKSPH 452

  Fly   472 HADDISYMF---YGILSSKLDKNSPEYRTIERLV-GMWTSFATTGDPN 515
            |::|:.|.|   .|:.:.|      :| .||.:. ||:..|....||:
 Worm   453 HSEDLIYTFGTHRGVFAPK------DY-VIEYIYSGMFADFINFEDPS 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	144/547 (26%)
		Aes	<117..>222	CDD:223730	38/118 (32%)
cest-1.2	NP_506504.2	COesterase	21..536	CDD:278561	146/552 (26%)
		Aes	<125..>250	CDD:223730	43/139 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157053
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.740