Protein Alignment gas and cest-35.2

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_504398.1
• Gene: cest-35.2 / 178910
• WormBaseID: WBGene00016863
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 538
• Identity: 159/538 - (29%)
• Similarity: 239/538 - (44%)
• Gaps: 122/538 - (22%)

  Fly    44 GQQRRTLYD-GEPYYS-FEGIPFAQPPVGELRFRAPQPPSSWQGVRDC-TYAREKP-------MQ 98
            |..|..:|: |:...: :.|||||:.|:|:|||:.......|....|| .|....|       :.
 Worm    22 GPIRGNVYEHGDKIVNGYLGIPFAKAPIGDLRFKKSVEAEKWTQPLDCYKYGPGCPQSAALGALM 86

  Fly    99 RNSITNAAEGSEDCLYLNVYA---KRLESPKPLPVMVWIFGGGFQVGGASRELYGPDYFMK---- 156
            .:..||.....::||.|||:|   |..|.|...||||:.:||||:||.:|   ...||.:.
 Worm    87 VSQATNHDFAEDNCLNLNVFAPKWKSAEFPNGFPVMVYFYGGGFEVGFSS---MFDDYSLTGTLP 148

  Fly   157 -HDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESA 220
             .|::|||.|||:|.|||.:..|...:  ||.||.||..||:||:::|.||.|||.::|:.|.||
 Worm   149 LKDVILVTPNYRIGPLGFFATGDDVAR--GNWGLWDQALALQWVQKHIKSFGGDPSNVTISGTSA 211

  Fly   221 GGASTHILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWPQRLGKEL------------GYAGN 273
            ||||...|..:..|...|.:.|..||:|.|.:..:         .|::            ||.||
 Worm   212 GGASVDFLSLSPHANKYFQKFIPMSGAATCPFGIR---------SKDVEGLIFREFANHHGYTGN 267

  Fly   274 LESEKELLEFFQ-------------QIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDC 325
              ..|.||:::|             :.|||.:                  .:|.|..:   ||
 Worm   268 --DSKSLLQWYQSQDSEIFLKAEGYKCPASGM------------------FSFVPNFD---GD-- 307

  Fly   326 VIPKSQQEQLSSAWGNSIPMIIG---GTSFEGLFSYRTTLDDPLYMLSAFEAIIPKQVRDAIDKE 387
            ..||...|....|......:.||   |..||..::.:.|   |..||||  |:.|:.||:.
 Worm   308 FFPKPFDELRKEAPKLGAIVSIGEYEGLGFEDFYAGQKT---PQQMLSA--ALGPEVVRNR---- 363

  Fly   388 ELAEMVRRLKKSYF-----DDPDRASMELYECL--HILSIKNFWHDIHRTLLARLAYATNLPTYL 445
              .|:|:|..:||.     ::.:..:..|.|..  :..|:..|  |..|:|   :.|...:  ||
 Worm   364 --EEVVKRAAESYLKNGGNENEENIAKTLVEIFGDYYFSVGAF--DTVRSL---VKYGNTV--YL 419

  Fly   446 YRFDMDSPHFNHYRILKCGKK--VRGVCHADDISYMFYGILSSKLDKNSPEYRTIERLVGMW-TS 507
            |.|:    :||....:..||.  .....|..|:.|:|    .....:.|.|.|.:..::|.: |:
 Worm   420 YSFN----YFNPNTPIVFGKNRPFNAANHGSDLRYIF----GEGTGEFSKEDRQVMDMMGTYHTN 476

  Fly   508 FATTGDPNCEIIAPVKWD 525
            ||..|:||.:.:: |.|:
 Worm   477 FAKYGNPNGKGVS-VPWE 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	159/538 (30%)
		Aes	<117..>222	CDD:223730	50/112 (45%)
cest-35.2	NP_504398.1	COesterase	14..515	CDD:278561	159/538 (30%)
		Aes	<105..>239	CDD:223730	60/138 (43%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157284
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D206516at33208
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.650