Protein Alignment gas and cest-4

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_501043.1
• Gene: cest-4 / 177445
• WormBaseID: WBGene00015930
• Length: 592
• Species: Caenorhabditis elegans
• Alignment Length: 534
• Identity: 130/534 - (24%)
• Similarity: 218/534 - (40%)
• Gaps: 123/534 - (23%)

  Fly    35 LATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCTYAREKPMQR 99
            ::|..||:.|.|..:      ::.|:.||.|:||:|:|||:.|:||..|.|||:........:..
 Worm    29 VSTSLGQIDGDQIGS------FHLFKHIPLAKPPIGKLRFQKPEPPEKWTGVRNAKAYGPACISN 87

  Fly   100 NSITNAAEG--SEDCLYLNVYA--KRLESPKPLPVMVWIFGGGFQVGGASRELYGPDY----FMK 156
            :|::.:.:.  .||||::|::.  |.|:| |...|:.:..|||.....|  .::...|    |:.
 Worm    88 SSVSTSPQKWIDEDCLHINIFTSDKCLKS-KDCAVVTYFHGGGLMYDSA--VMFNDTYLLGTFVN 149

  Fly   157 HDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAG 221
            .|:::....:|:|:.....::|:.: .|.|..|.|.:..:.:||..|.:|.|:.:..|:.|.|.|
 Worm   150 QDVIIAIPAFRLGIFSHFVVEDQSI-APTNLALYDILLGVEFVKNEIHNFGGNNQKNTIMGHSYG 213

  Fly   222 GASTHILMQTEQAR---GLFHRAI-VQSGSALCAWATQPDRKWPQRLGKELGYAGNLESEKELLE 282
            |:..:||..:.:..   .||.::| :.||........|..:  ..|..|..|.......||::..
 Worm   214 GSIVNILTFSSKINHDLSLFQQSICMSSGHDFETLEIQIQK--TNRFAKHAGCTVPSIIEKKMTT 276

  Fly   283 FFQQIPASKLAQYCNSIVTQEEQR-----DYEILAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNS 342
            ....:...|..|..:::.....||     .|....:....||.:.:   ||  .||.:.|.  ..
 Worm   277 RQSDLYRMKCLQNKDALELLRVQRLLEDEGYPTYGYLVQREPLIQE---IP--YQEFMKSP--KK 334

  Fly   343 IPMIIGGTSFEGLFSYRTTLDDPLYMLSAFEAIIPKQVRDAIDKEELAEMVRRLKKSYFDDPDRA 407
            |||:.|.|.:|        :|         .:..||.:..|:..|...|:..:.:|.:.|
 Worm   335 IPMLTGCTRYE--------MD---------HSPAPKPIGQALGFENPEEVYMKFRKDWDD----- 377

  Fly   408 SMELYECLHILSIKNFWHDIHRT-------------LLARLAYATNLPTYLYRFDMDSPHFNHYR 459
              |:||         |.:....|             ||::     |:|.|||.:    .:..|.|
 Worm   378 --EVYE---------FGNHSDETQAIMVQVRVRVNNLLSK-----NVPAYLYEY----TYPKHAR 422

  Fly   460 ILKCGKKVRGVCHADDISYMFYGILSSKLDKNSPE----YRTIERLVGMWTSFATTGDP------ 514
                        |.||:.|:. |:...:.|:|..|    |.||      :.:||..|||
 Worm   423 ------------HTDDLFYLM-GVHRFEKDENEIELGKVYETI------FMNFAKFGDPKEGFEL 468

  Fly   515 ---NCEIIAPVKWD 525
               ..|....|.||
 Worm   469 ANAENESYYEVYWD 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	130/534 (24%)
		Aes	<117..>222	CDD:223730	27/110 (25%)
cest-4	NP_501043.1	Abhydrolase	28..503	CDD:389770	130/534 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810