Protein Alignment gas and cest-25

DIOPT Version :10

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_497609.1
• Gene: cest-25 / 175390
• WormBaseID: WBGene00022178
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 171/548 - (31%)
• Similarity: 266/548 - (48%)
• Gaps: 75/548 - (13%)

  Fly    13 LGAKIIGHKVVQYKLGTGQTKELATKYGQLKGQQRRTLYDGEPYY-SFEGIPFAQPPVGELRFRA 76
            :|..:..|....|.    .::::.|.||.::|  ||.:::||... :|:|||:|.||:|.|||..
 Worm     1 MGGTVSKHTTPHYP----PSRQVLTSYGPIEG--RRLIHEGEKQVDAFQGIPYAAPPIGNLRFAL 59

  Fly    77 PQPPSSWQGVRDCTYAREKPMQRNSITN--AAEGSEDCLYLNVYAKRLESPK---PLPVMVWIFG 136
            |||...|..||:......:.:|::.:.:  .:..|||.|.||::.. :.:||   ..||:::|.|
 Worm    60 PQPHEKWTEVRETKSFGARGIQKDHVLSPKTSPQSEDNLTLNIFTP-VWTPKNETGFPVILYIHG 123

  Fly   137 GGFQVGGASRELYGPDYFMKH----DILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALR 197
            |||....|.:  ||.....:|    |:::|||.||:|.|||.:..|.  .||.|..|.|.:.||:
 Worm   124 GGFVSDSAHK--YGDMSICQHLVTKDVVVVTIQYRLGFLGFWTTGDS--SIPDNVALHDMVFALK 184

  Fly   198 WVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWP- 261
            ||||||..|||||.:||:.|:||||||...|..:..:|.||.:.|...|:|.|:||..|.   |
 Worm   185 WVKENIGLFNGDPNNITLMGQSAGGASVDFLSISPVSRDLFQKVIPMGGNASCSWAIHPR---PL 246

  Fly   262 ---QRLGKELGYAGNLESEKELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVG- 322
               :...:|:|....:.: .:.:|..:::||.|.|...| :...:.:.|.|:|         :|
 Worm   247 NACRNRAQEIGVFDGMNT-LDWVEKLRELPADKFASALN-MEAVDTKTDPELL---------IGP 300

  Fly   323 --DDCVIPKSQQEQLSSAWGNSIPMIIGGTSFEGL----FSYRTTLDDPLYM----LSAF--EAI 375
              |:..||:...|....|  ...|.::|....|||    |...|  ..||:.    :||.  |.:
 Worm   301 KYDNLFIPRPVMELRKEA--PMKPRLLGCAKSEGLVFAFFGLNT--KHPLHAVQQDVSAILSEKL 361

  Fly   376 IPKQVRDAIDK--EELAEMVRRLKKSYFDDPDRASMELYECLHILSIKNFWH-DIHRTLLARLAY 437
            .|.:.||..:|  |:|.|:          ..|.:..|....:..|...:|.: .|.:.:|..|..
 Worm   362 FPLKARDYQEKALEKLIEI----------GTDHSKEEWQRAMVDLKGDSFLNVGIQQNVLDVLET 416

  Fly   438 ATNLPTYLYRFDMDSPHFNHYRILKCGKKVRGVCHADDISYMFYGILSSKLDKNSPEYRTIERLV 502
            ..:.|.|:|.||..:|  ..|.|:......:...|..||||:....:.:..|.|..:|:.||...
 Worm   417 QPSTPIYMYSFDYCNP--KAYGIMGFKLPFKDATHCTDISYVVGNHIVNSFDFNEEDYKMIEITT 479

  Fly   503 GMWTSFATTGDPNCE--IIAPV--KWDP 526
            .:||:||..|:||.|  .:|.:  ||:|
 Worm   480 RLWTNFAKYGNPNGEGDDVAHLEEKWEP 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	31..529	CDD:395084	168/530 (32%)
cest-25	NP_497609.1	COesterase	15..536	CDD:395084	168/530 (32%)