Protein Alignment gas and cest-25

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_497609.1
• Gene: cest-25 / 175390
• WormBaseID: WBGene00022178
• Length: 550
• Species: Caenorhabditis elegans
• Alignment Length: 548
• Identity: 171/548 - (31%)
• Similarity: 266/548 - (48%)
• Gaps: 75/548 - (13%)

  Fly    13 LGAKIIGHKVVQYKLGTGQTKELATKYGQLKGQQRRTLYDGEPYY-SFEGIPFAQPPVGELRFRA 76
            :|..:..|....|.    .::::.|.||.::|  ||.:::||... :|:|||:|.||:|.|||..
 Worm     1 MGGTVSKHTTPHYP----PSRQVLTSYGPIEG--RRLIHEGEKQVDAFQGIPYAAPPIGNLRFAL 59

  Fly    77 PQPPSSWQGVRDCTYAREKPMQRNSITN--AAEGSEDCLYLNVYAKRLESPK---PLPVMVWIFG 136
            |||...|..||:......:.:|::.:.:  .:..|||.|.||::.. :.:||   ..||:::|.|
 Worm    60 PQPHEKWTEVRETKSFGARGIQKDHVLSPKTSPQSEDNLTLNIFTP-VWTPKNETGFPVILYIHG 123

  Fly   137 GGFQVGGASRELYGPDYFMKH----DILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALR 197
            |||....|.:  ||.....:|    |:::|||.||:|.|||.:..|.  .||.|..|.|.:.||:
 Worm   124 GGFVSDSAHK--YGDMSICQHLVTKDVVVVTIQYRLGFLGFWTTGDS--SIPDNVALHDMVFALK 184

  Fly   198 WVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWP- 261
            ||||||..|||||.:||:.|:||||||...|..:..:|.||.:.|...|:|.|:||..|.   |
 Worm   185 WVKENIGLFNGDPNNITLMGQSAGGASVDFLSISPVSRDLFQKVIPMGGNASCSWAIHPR---PL 246

  Fly   262 ---QRLGKELGYAGNLESEKELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVG- 322
               :...:|:|....:.: .:.:|..:::||.|.|...| :...:.:.|.|:|         :|
 Worm   247 NACRNRAQEIGVFDGMNT-LDWVEKLRELPADKFASALN-MEAVDTKTDPELL---------IGP 300

  Fly   323 --DDCVIPKSQQEQLSSAWGNSIPMIIGGTSFEGL----FSYRTTLDDPLYM----LSAF--EAI 375
              |:..||:...|....|  ...|.::|....|||    |...|  ..||:.    :||.  |.:
 Worm   301 KYDNLFIPRPVMELRKEA--PMKPRLLGCAKSEGLVFAFFGLNT--KHPLHAVQQDVSAILSEKL 361

  Fly   376 IPKQVRDAIDK--EELAEMVRRLKKSYFDDPDRASMELYECLHILSIKNFWH-DIHRTLLARLAY 437
            .|.:.||..:|  |:|.|:          ..|.:..|....:..|...:|.: .|.:.:|..|..
 Worm   362 FPLKARDYQEKALEKLIEI----------GTDHSKEEWQRAMVDLKGDSFLNVGIQQNVLDVLET 416

  Fly   438 ATNLPTYLYRFDMDSPHFNHYRILKCGKKVRGVCHADDISYMFYGILSSKLDKNSPEYRTIERLV 502
            ..:.|.|:|.||..:|  ..|.|:......:...|..||||:....:.:..|.|..:|:.||...
 Worm   417 QPSTPIYMYSFDYCNP--KAYGIMGFKLPFKDATHCTDISYVVGNHIVNSFDFNEEDYKMIEITT 479

  Fly   503 GMWTSFATTGDPNCE--IIAPV--KWDP 526
            .:||:||..|:||.|  .:|.:  ||:|
 Worm   480 RLWTNFAKYGNPNGEGDDVAHLEEKWEP 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	168/533 (32%)
		Aes	<117..>222	CDD:223730	47/111 (42%)
cest-25	NP_497609.1	COesterase	18..536	CDD:365897	168/527 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	1	1.000	-	-		otm14771
orthoMCL	1	0.900	-	-		OOG6_100080
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X33
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.710