Protein Alignment gas and ace-4

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_496962.1
• Gene: ace-4 / 175074
• WormBaseID: WBGene00000038
• Length: 602
• Species: Caenorhabditis elegans
• Alignment Length: 613
• Identity: 164/613 - (26%)
• Similarity: 227/613 - (37%)
• Gaps: 156/613 - (25%)

  Fly    35 LATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCTYAREKPMQR 99
            |.||.|.:||.:  ..:..:...:|.|:|||:|.|.:.|||.|:....|:|:.|.|.......|.
 Worm    29 LETKLGDIKGTE--FFFLSKKIRTFFGVPFAEPAVEDFRFRKPREKKQWRGLYDATKPANACFQT 91

  Fly   100 NSITNAA-----------EGSEDCLYLNVYAKRLESPKPLPVMVWIFGGGFQVGGASRELY-GPD 152
            ....|.:           :.||||||||::|.  .....|.||||.|||||..|..|..:| |..
 Worm    92 RDNYNTSFWGSEMWNANTQISEDCLYLNIWAP--ADAYNLTVMVWFFGGGFYSGSPSLSIYDGKA 154

  Fly   153 YFMKHDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFG 217
            .....::::|.||||:|..|||.|...:  .|||.||.||..||.||::||.||.|:|:.:.|||
 Worm   155 LTSTQNVIVVNINYRLGPFGFLYLGHPD--APGNMGLLDQQLALHWVRQNIVSFGGNPDKVAVFG 217

  Fly   218 ESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWATQPDRKWPQRLGKELGYAGNLESEKELLE 282
            :|||.||....:....:||||..||:||||....||.....:..|:            ||| |||
 Worm   218 QSAGAASIVAHLIAPGSRGLFKNAILQSGSLENTWAINSPFRAKQK------------SEK-LLE 269

  Fly   283 FFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPKSQQEQLS-SAWGNSI--- 343
            ...          ||.......      :|...::.|             |||| |.|..|:
 Worm   270 LVG----------CNKTTVDTS------MACLRLVSP-------------EQLSLSTWNISLTYL 305

  Fly   344 --PMII-------------GGTSFEGLFSYRTTL------DD----PLYMLSAFEAIIPKQVRDA 383
              |.:|             .....||.|:....|      |:    .:|.|..|        .|.
 Worm   306 EFPFVIVSRDKHFFGHLDAHAALREGDFNRDVNLMIGMNKDEGNYWNIYQLPQF--------FDK 362

  Fly   384 IDKEEL----------------AEMVRRLKKSYFDDPD-----------RASMELYECLHILSIK 421
            .|..||                .:::|...|..:.||:           ...|......:..|..
 Worm   363 ADPPELNRTEFDFLIDRTFSIQPDIIRSAAKYIYSDPNCTDHGRKTRFYAGQMNQIVGDYFFSCD 427

  Fly   422 NFW-HDIHRTLLARLAYATNLPTYLYRFDMDSP----------HFNHYRILKCGKKVRGVCHADD 475
            :.| .|..|          ::|    |....||          ||..........|..|..|..:
 Worm   428 SLWLADQFR----------SIP----RVKSSSPQRKPGKVFVYHFTQSSSANPWPKWTGAMHGYE 478

  Fly   476 ISYMFYGILSSKLDKNSPEYRTIERLVGMWTSFATTGDPNCEIIAPVK-WDPLRPGGVENCLNIA 539
            |.|:|...||...:....|.....:::..|.|||..|.|...::...: |...........:.:.
 Worm   479 IEYVFGIPLSYSKNYKRREQIFSRKIMQFWASFAKNGTPKLRVLKNSEHWPEFNEQNHYRWMQLR 543

  Fly   540 DGLEFIPLPESKQFV------VWDSFYT 561
            .|....|:...||..      |.|:.||
 Worm   544 SGSNIRPIKPKKQVECQFWRRVKDTEYT 571

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	156/578 (27%)
		Aes	<117..>222	CDD:223730	47/105 (45%)
ace-4	NP_496962.1	COesterase	28..562	CDD:278561	160/602 (27%)
		Aes	<120..>243	CDD:223730	55/126 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160156982
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.928771	Normalized mean entropy	S6126
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.790