Protein Alignment gas and Nlgn3

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: NP_599163.2
• Gene: Nlgn3 / 171297
• RGDID: 621119
• Length: 848
• Species: Rattus norvegicus
• Alignment Length: 650
• Identity: 187/650 - (28%)
• Similarity: 265/650 - (40%)
• Gaps: 212/650 - (32%)

  Fly    37 TKYGQLKGQQRRTLYDGE---PYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCTYAREKPMQ 98
            |.:|:|:|  .|.....|   |...:.|:|:|.||:||.||..|:||.||.|:|:.|:.  .|:.
  Rat    46 THFGKLRG--ARVPLPSEILGPVDQYLGVPYAAPPIGEKRFLPPEPPPSWSGIRNATHF--PPVC 106

  Fly    99 RNSITNAA---------------------EGSEDCLYLNVY-----AKRLE---SPKP------- 127
            ..:|..|.                     |.:|||||||||     .||:.   :.||
  Rat   107 PQNIHTAVPEVMLPVWFTANLDIVATYIQEPNEDCLYLNVYVPTEDVKRISKECARKPNKKICRK 171

  Fly   128 ----------------------------LPVMVWIFGGGFQVG------GASRELYGPDYFMKHD 158
                                        .||||:|.||.:..|      |:....||       :
  Rat   172 GGSGAKKQGEDLADNDGDEDEDIRDSGAKPVMVYIHGGSYMEGTGNMIDGSVLASYG-------N 229

  Fly   159 ILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAGGA 223
            ::::|:|||||||||||..|:..|  ||.||.|||||||||.||||.|.|||..|||||...|.:
  Rat   230 VIVITLNYRVGVLGFLSTGDQAAK--GNYGLLDQIQALRWVSENIAFFGGDPRRITVFGSGIGAS 292

  Fly   224 STHILMQTEQARGLFHRAIVQSGSALCAWAT--QPDRKWPQRLGKELGYAGNLESEKELLEFFQQ 286
            ...:|..:..:.|||.|||:||||||.:||.  || .|:...|..::|.  |:....::::..:|
  Rat   293 CVSLLTLSHHSEGLFQRAIIQSGSALSSWAVNYQP-VKYTSLLADKVGC--NVLDTVDMVDCLRQ 354

  Fly   287 IPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIGGTS 351
            ..|.:|       |.|:.|.....:||.|||:   ||  |||...:..:......:..:::|...
  Rat   355 KSAKEL-------VEQDIQPARYHVAFGPVID---GD--VIPDDPEILMEQGEFLNYDIMLGVNQ 407

  Fly   352 FEGLFSYRTTLD--------DPLYMLSAFEAIIPKQVRDAID--------KEELAEMVRRLKKSY 400
            .|||......:|        |..|.:|.|           :|        |:.|.|.:   |..|
  Rat   408 GEGLKFVEGVVDPEDGVSGTDFDYSVSNF-----------VDNLYGYPEGKDTLRETI---KFMY 458

  Fly   401 FDDPDRASMEL-YECLHILSIKNFW-------HDIHRTLLARLAYATNLPTYLYRFDMDSPHFNH 457
            .|..||.:.|. .:.|..|...:.|       .|:|    ||  |.:  |||.|.|      ::|
  Rat   459 TDWADRDNPETRRKTLVALFTDHQWVEPSVVTADLH----AR--YGS--PTYFYAF------YHH 509

  Fly   458 YRILKCGKKVR----GVCHADDISYMF-------YGILSSKLDKNSPEYRTIERLVGMWTSFATT 511
                 |...::    ...|.|::.|:|       ..:......||......:  ::..||:||.|
  Rat   510 -----CQSLMKPAWSDAAHGDEVPYVFGVPMVGPTDLFPCNFSKNDVMLSAV--VMTYWTNFAKT 567

  Fly   512 GDPNCEIIAPVKWDPLRPGGVENCLNIADGLEFIPLPESKQF----------VVWDSFYTRESLY 566
            ||||                             .|:|:..:|          |.|..:..|:.||
  Rat   568 GDPN-----------------------------KPVPQDTKFIHTKANRFEEVAWSKYNPRDQLY 603

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	179/606 (30%)
		Aes	<117..>222	CDD:223730	57/153 (37%)
Nlgn3	NP_599163.2	COesterase	40..624	CDD:395084	186/649 (29%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	169..195		0/25 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	645..691

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336090
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.740