DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment gas and bche

DIOPT Version :9

Sequence 1:	NP_611678.1	Gene:	gas / 37572	FlyBaseID:	FBgn0034736	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	XP_002931610.1	Gene:	bche / 100495889	XenbaseID:	XB-GENE-980117	Length:	602	Species:	Xenopus tropicalis

Alignment Length:	591	Identity:	171/591 - (28%)
Similarity:	259/591 - (43%)	Gaps:	120/591 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 GQTKELATKYGQLKGQQRRTLYDGEPYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCT-YAR 93
            |:|..:.||||::.|.| .:::.| ...:|.|||:|:||:|:|||:.|.|...|..:.:.: |..
Frog    28 GETDIVDTKYGKVTGVQ-ISVFSG-IITAFLGIPYAEPPIGDLRFKKPVPHKPWSEIWNASQYGN 90

  Fly    94 EKPMQRNSITNAAEG----------SEDCLYLNVYAKRLESPKP--LPVMVWIFGGGFQVGGASR 146
            ......:.|.....|          ||||||||::   :.:|||  ..|||||:||.|:.|.:|.
Frog    91 SCYQTVDQIFPGFSGAEMWNPNTQLSEDCLYLNIW---IPTPKPRNASVMVWIYGGSFETGTSSL 152

  Fly   147 ELYGPDYFMKHD-ILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDP 210
            :||...:..:.: :::|::|||:|.||||:..... :.|||.||.||..||:||.||||:|.|:|
Frog   153 DLYDGKFLARTERVIVVSMNYRLGALGFLAFPGNN-EAPGNVGLFDQRLALQWVYENIAAFGGNP 216

  Fly   211 ESITVFGESAGGASTHILMQTEQARGLFHRAIVQSGSALCAWA--TQPDRKWPQRLGKELGYAGN 273
            :|||:|||||||||....|.:.::.|.|.|||:||.:|...||  |:.:..     .:.|..|
Frog   217 KSITIFGESAGGASVSYHMLSPKSHGFFTRAIMQSATANAPWAVITKAEAS-----NRALTLA-- 274

  Fly   274 LESEKELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIE----PYVGDDCVI--PK--S 330
                 .||..|.:.....:|...|....:..::...:|....|||    |.|..|.:|  |:  .
Frog   275 -----NLLNCFYRNETEIIACLRNKSPEEIFEKAVSVLPHRSVIEVNFPPTVDGDFLIEMPEILM 334

  Fly   331 QQEQLSSAWGNSIPMIIGGTSFEGLFSYRTTLDDPLYMLSAF----EAII-----PKQVRDAIDK 386
            |..||.    ....::.|....||.:..       :|.|..|    |:.|     .|.|:.|..|
Frog   335 QLGQLK----KKTQILTGVNKDEGSYFL-------VYGLPGFSKDHESFINRTQFHKSVKLAFPK 388

  Fly   387 -EELAEMVRRLKKSYFDDPDRASMELYECLHILSIKNF---------WHDIHRTLLARLAYATNL 441
             .|||........:.::|....|........|:...||         |:.         ....|
Frog   389 ATELAIDSVLFHYTNWEDEQNPSHNRDAMDDIVGDYNFICPLLEFTKWNS---------ELGNN- 443

  Fly   442 PTYLYRFDMDSPHFNHYRILKCGKKV-----RGVCHADDISYMFYGILSSKLDKNSPEYRTIERL 501
             .|||.|        |:|    ..|:     .||.|..:|.::|...:..:|:....|......|
Frog   444 -AYLYYF--------HHR----SSKLTWPGWMGVMHGYEIEFVFGIPMYRRLNYTKAEETLSRTL 495

  Fly   502 VGMWTSFATTGDPNCEIIAPVKWDPLRPGGVENCLNIADGLEFIPL----------PESKQFVVW 556
            :..|.:||.||:||....:..:|.          :...|...::.|          ..:||...|
Frog   496 MRYWANFAKTGNPNGAQSSENRWP----------VFTLDEQHYLMLGTEDSKTNRKMRAKQCRFW 550

  Fly   557 DSFYTR 562
            ::||.:
Frog   551 NNFYPK 556

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	164/551 (30%)
gas	NP_611678.1	Aes	<117..>222	CDD:223730	50/107 (47%)
bche	XP_002931610.1	COesterase	32..550	CDD:365897	166/579 (29%)
bche	XP_002931610.1	AChE_tetra	565..599	CDD:370053
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910