Protein Alignment gas and nlgn1

DIOPT Version :10

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_017949302.2
• Gene: nlgn1 / 100329186
• XenbaseID: XB-GENE-6041753
• Length: 859
• Species: Xenopus tropicalis
• Alignment Length: 653
• Identity: 184/653 - (28%)
• Similarity: 266/653 - (40%)
• Gaps: 207/653 - (31%)

  Fly    37 TKYGQLKGQQRRTLYDGE---PYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCT-YAREKPM 97
            |.||:::|.::.  .:.|   |...|.|:|:|.||:||.||:.|:||:.|..:::.| :|...|
 Frog    57 TTYGKVRGFKKE--LNNEILGPVVQFLGVPYAAPPIGERRFQPPEPPTMWGDIKNSTQFAPVCP- 118

  Fly    98 QRNSI-------------TN--------AAEGSEDCLYLNVY-----AKRL-------------- 122
             :|.:             ||        ..:.||||||||:|     .||:
 Frog   119 -QNIVGGRLPEVMLPVWFTNNLDVVSSYVQDQSEDCLYLNIYVPTEDVKRISKECARKPGKKICR 182

  Fly   123 -------------------------ESPKPLPVMVWIFGGGFQVG------GASRELYGPDYFMK 156
                                     :|..|.||||:|.||.:..|      |:....||
 Frog   183 KEGPLTKKQTDDLGDNEGAEDEDIRDSGGPKPVMVYIHGGSYMEGTGNVFDGSVLASYG------ 241

  Fly   157 HDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAG 221
             :::::|:|||:|||||||..|:..|  ||.||.|.||||||..|||..|.|||..|||||..||
 Frog   242 -NVIVITVNYRLGVLGFLSTGDQASK--GNYGLLDLIQALRWTSENIGFFGGDPLRITVFGSGAG 303

  Fly   222 GASTHIL---------MQTEQARGLFHRAIVQSGSALCAWAT--QPDRKWPQRLGKELGYAGNLE 275
            .:..::|         ..:...:|||.|||.|||:||.:||.  || .|:.:.|..::|.  |:.
 Frog   304 ASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQP-AKYARILATKVGC--NMS 365

  Fly   276 SEKELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPKSQQEQLSSAWG 340
            ...||:|..|:.|..:|       |.|:.|.....:||.|||:   ||  |||...|..:.....
 Frog   366 DSGELVECLQKKPYREL-------VDQDIQPVRYHIAFGPVID---GD--VIPDDPQVLMEQGEF 418

  Fly   341 NSIPMIIGGTSFEGLFSYRTTLD-DPLYMLSAFEAIIPKQVRDAIDKEELAEMVRR-LKKSYFDD 403
            .:..:::|....|||....:|:| :.....|.|:..:...|.:.....|..:::|. :|..|.|.
 Frog   419 LNYDIMLGVNQGEGLKFVESTVDHEDGVSSSDFDFAVSNFVDNLYGYTEGKDILRETIKFMYTDW 483

  Fly   404 PDRASMELYECLHILSIKNFWHDIHRTLLARL--------AYAT-------NLPTYLYRFDMDSP 453
            .||.:.|..               .:||||..        |.||       ..|||.|.|
 Frog   484 ADRNNPETR---------------RKTLLALFTDHQWVAPAVATADLHSNFGSPTYFYAF----- 528

  Fly   454 HFNHYRILKCGKKVRGVC------------HADDISYMFYGI--------LSSKLDKNSPEYRTI 498
             ::|             |            |.|:|.|:| ||        ......||......:
 Frog   529 -YHH-------------CQTDQVPAWADASHGDEIPYVF-GIPMIGPTELFPCNFSKNDVMLSAV 578

  Fly   499 ERLVGMWTSFATTGDPNCEIIAPVKWDPLRPGGVENCLNIADGLEFIPLPESKQFVVWDSFYTRE 563
              ::..||:||.|||||..:....|:...:|...|.                   |.|..:..::
 Frog   579 --VMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEE-------------------VAWTRYSQKD 622

  Fly   564 SLY 566
            .||
 Frog   623 QLY 625

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	31..529	CDD:395084	178/614 (29%)
nlgn1	XP_017949302.2	COesterase	52..646	CDD:395084	184/653 (28%)