DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment gas and cel.2

DIOPT Version :9

Sequence 1:	NP_611678.1	Gene:	gas / 37572	FlyBaseID:	FBgn0034736	Length:	566	Species:	Drosophila melanogaster
Sequence 2:	NP_001120027.1	Gene:	cel.2 / 100144991	XenbaseID:	XB-GENE-1217488	Length:	552	Species:	Xenopus tropicalis

Alignment Length:	503	Identity:	172/503 - (34%)
Similarity:	235/503 - (46%)	Gaps:	81/503 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    59 FEGIPFAQPPVGELRFRAPQPPSSWQGVRDCTYAREKPMQRNSITNAAEGSEDCLYLNVYAKRLE 123
            |:|||||.||   ..|...:....|.|.......:.:.:|.....:...||.|||||||:..:..
Frog    50 FKGIPFAAPP---KPFEKAEKHPGWSGTLQAKDYKPRCLQATITQDNVFGSLDCLYLNVWVPQTR 111

  Fly   124 S--PKPLPVMVWIFGGGFQVG---GA---SRELY-GPDYFMKHDILLVTINYRVGVLGFLSLKDK 179
            |  ...||||||||||||.:|   ||   |..|| |.:..|:..:::||.|||||.|||||..|.
Frog   112 SQVSTNLPVMVWIFGGGFLLGSGQGANFLSNYLYDGEEVAMRGKVIVVTFNYRVGPLGFLSTGDS 176

  Fly   180 ELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAGGASTHILMQTEQARGLFHRAIVQ 244
              ..|||.||.||..|:.|||.|||:|.|||.:||:|||||||||..:...|....||..|||.|
Frog   177 --NAPGNYGLWDQHMAIAWVKRNIAAFGGDPNNITLFGESAGGASVSLQTLTPYNVGLIKRAISQ 239

  Fly   245 SGSALCAWATQPD-RKWPQRLGKELGYAGNLESEKELLEFFQQI-PASKLAQYCNSIVTQEEQRD 307
            ||..||.||.|.| ..|.:.|..:||...|  :.|||.:..:.. |.:....|...:...|
Frog   240 SGVGLCPWAIQRDPLTWAKSLASKLGCPVN--NTKELADCLRNTDPGALTIAYQLQLFNLE---- 298

  Fly   308 YEI---LAFAPVIEPYVGDDCVIPKSQQEQLSSAWGNSIPMIIGGTSFEG-LFS--YRTTLDDPL 366
            |.:   ||::|||:   ||  .||...:...|:|.|  :..|.|..:.:| ||:  ....::.||
Frog   299 YPLVHYLAYSPVID---GD--FIPDEPRNLFSNAAG--VDYIAGVNNMDGHLFAGVDLPAINQPL 356

  Fly   367 YMLSAFEAIIPKQVRDAIDKEELAEMVRRLKKSY------------FDDPDRASMELYECLHILS 419
            :.:|.      :||:..:....||:.|..|..:|            .:|..|..:|: |..:|..
Frog   357 HKIST------EQVQKVVRGLTLAKGVPALDIAYDLYTAGWGTNPSQEDMKRTVVEV-ETDYIFL 414

  Fly   420 IKNFWHDIHRTLLARLAYATNLPTYLYRFDMDS--PHFNHYRILKCGKKVRGVCHADDISYMFYG 482
            :..     ...|......|....||.|.|...|  |.:..:         .|..||:|:.:||..
Frog   415 VAT-----QEALALHYQNAKGAKTYSYMFSHPSRMPVYPSW---------MGADHAEDLQFMFGK 465

  Fly   483 ILSSKL-----DKNSPEYRTIERLVGMWTSFATTGDPN-CEIIAPVKW 524
            ..|:.|     |::..:|     ::..||:||.||||: .|...|..|
Frog   466 PFSTPLAYRPRDRDVAQY-----MIAYWTNFAATGDPSKGESSIPTPW 508

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	172/503 (34%)
gas	NP_611678.1	Aes	<117..>222	CDD:223730	60/113 (53%)
cel.2	NP_001120027.1	COesterase	24..542	CDD:365897	172/503 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000017
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000