Protein Alignment gas and nlgn1

DIOPT Version :9

• Sequence 1: NP_611678.1
• Gene: gas / 37572
• FlyBaseID: FBgn0034736
• Length: 566
• Species: Drosophila melanogaster
• Sequence 2: XP_017213657.1
• Gene: nlgn1 / 100002610
• ZFINID: ZDB-GENE-090918-1
• Length: 867
• Species: Danio rerio
• Alignment Length: 655
• Identity: 184/655 - (28%)
• Similarity: 267/655 - (40%)
• Gaps: 207/655 - (31%)

  Fly    35 LATKYGQLKGQQRRTLYDGE---PYYSFEGIPFAQPPVGELRFRAPQPPSSWQGVRDCT-YAREK 95
            :.|.||:::|.::.  .:.|   |...|.|:|:|.||.||.||:.|:||.||..:|:.| :|...
Zfish    56 VTTTYGKVRGFKKE--LNNEILGPVIQFLGVPYAAPPTGERRFQPPEPPISWSEIRNATQFAPVC 118

  Fly    96 PMQ---------------RNSI----TNAAEGSEDCLYLNVY-----AKRL-------------- 122
            |..               .|||    :...:.|||||:||:|     .||:
Zfish   119 PQTLLEGRLPDVMLPVWFTNSIEVVSSYVQDQSEDCLFLNIYVPTEDVKRISKECARKPGKKICR 183

  Fly   123 -------------------------ESPKPLPVMVWIFGGGFQVG------GASRELYGPDYFMK 156
                                     ||..|.||||::.||.:..|      |:....||
Zfish   184 KGGPLSKKQNDDLADNDGAEDEDIRESGSPKPVMVFVHGGSYMEGTGNMFDGSILASYG------ 242

  Fly   157 HDILLVTINYRVGVLGFLSLKDKELKIPGNAGLKDQIQALRWVKENIASFNGDPESITVFGESAG 221
             :::::|:|||:|||||||..|:..|  ||.||.|.||||||..||||.|.|||..|||||..||
Zfish   243 -NVIVITVNYRLGVLGFLSTGDQAAK--GNYGLLDLIQALRWTSENIAFFGGDPLRITVFGSGAG 304

  Fly   222 GASTHIL---------MQTEQARGLFHRAIVQSGSALCAWAT--QPDRKWPQRLGKELGYAGNLE 275
            .:..::|         ..:...:|||.|||.|||:||.:||.  || .|:.:.|.|::|.  ||:
Zfish   305 ASCVNLLTLSHYSEGNRWSNSTKGLFQRAIAQSGTALSSWAVSFQP-AKYARMLAKKVGC--NLK 366

  Fly   276 SEKELLEFFQQIPASKLAQYCNSIVTQEEQRDYEILAFAPVIEPYVGDDCVIPKSQQEQLSSAWG 340
            ...|::|..|:       ::...:|.|:.|.....:||.|||:   ||  |||...|..:.....
Zfish   367 DTVEMVECLQK-------KHYKELVEQDIQPARYHIAFGPVID---GD--VIPDDPQILMEQGEF 419

  Fly   341 NSIPMIIGGTSFEGLFSYRTTLD--------DPLYMLSAFEAIIPKQVRDAIDKEELAEMVRRLK 397
            .:..:::|....|||......:|        |..|.:|:|       |.|.....|..:::|...
Zfish   420 LNYDIMLGVNQGEGLKFVELIVDNENGVQANDFDYAVSSF-------VDDLYGYPEGKDILRETI 477

  Fly   398 KSYFDDPDRASMELYECLHILSIKNFWHDIH------RTLLARL--------AYAT-------NL 441
            |..:.|                    |.|.|      :||||..        |.||       ..
Zfish   478 KFMYTD--------------------WADRHNPETRRKTLLALFTDHQWVAPAVATADLHSSFGS 522

  Fly   442 PTYLYRFDMDSPHFNHYRILKCGKKV---RGVCHADDISYMF-------YGILSSKLDKNSPEYR 496
            |||.|.|      ::|.:.    ::|   ....|.|:|.|:|       ..:......||.....
Zfish   523 PTYFYAF------YHHCQT----EQVPPWADAAHGDEIPYVFGLPMIGPTELFPCNFSKNDVMLS 577

  Fly   497 TIERLVGMWTSFATTGDPNCEIIAPVKWDPLRPGGVENCLNIADGLEFIPLPESKQFVVWDSFYT 561
            .:  ::..||:||.|||||..:....|:...:|...|.                   |.|..:..
Zfish   578 AV--VMTYWTNFAKTGDPNQPVPQDTKFIHTKPNRFEE-------------------VAWTRYNQ 621

  Fly   562 RESLY 566
            ::.||
Zfish   622 KDQLY 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
gas	NP_611678.1	COesterase	28..534	CDD:278561	179/621 (29%)
		Aes	<117..>222	CDD:223730	54/154 (35%)
nlgn1	XP_017213657.1	COesterase	53..647	CDD:306613	184/655 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170575479
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1516
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.740