Protein Alignment CG4610 and MTO1

DIOPT Version :10

• Sequence 1: NP_611677.1
• Gene: CG4610 / 37571
• FlyBaseID: FBgn0034735
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_011278.2
• Gene: MTO1 / 852616
• SGDID: S000003205
• Length: 669
• Species: Saccharomyces cerevisiae
• Alignment Length: 636
• Identity: 286/636 - (44%)
• Similarity: 414/636 - (65%)
• Gaps: 24/636 - (3%)

  Fly    33 VVVIGGGHAGTEASAAAARMGSRTLLLTHKLETIGEMSCNPSFGGIGKGHLMREVDALDGVCARC 97
            |||||.||||.||:||::|.|:.|.|:|..|..||:.|||||.||:|||.|::|:|||||:..:.
Yeast    39 VVVIGAGHAGCEAAAASSRTGAHTTLITPSLTDIGKCSCNPSIGGVGKGILVKEIDALDGLMGKV 103

  Fly    98 CDVSGVHYKVLNRRRGPAVWGPRAQIDRQLYKKAVQQEL---HSTPNLEIRAAAVDNLLIEDEQD 159
            .|::||.:|:|||.:|||||||||||||:||||.:|:||   .:.|||.:....|.:|::.|.
Yeast   104 TDLAGVQFKMLNRSKGPAVWGPRAQIDRELYKKYMQRELSDKKAHPNLSLLQNKVADLILYDP-- 166

  Fly   160 TQARRC-----TGVLLANGEVVRSRSVVLTTGTFLRAHINIGLEVRPAGRIGDAPAKALGEAI-D 218
                .|     .||:|.:|..|.:..|::||||||.|.|:||.:...|||||:.|...:...: :
Yeast   167 ----GCGHKVIKGVVLDDGTQVGADQVIITTGTFLSAEIHIGDKRIAAGRIGEQPTYGISNTLQN 227

  Fly   219 RLGFRMGRLKTGTPPRIAKDSVDFSQLQRHEGDDPPMPFSFLNKDVWLPAKDQLPCYLTYTTPKV 283
            .:||::||||||||.|:||:|:|||.|:..:||..|:|.||||:.|.:....||.|:.|:|||::
Yeast   228 EVGFQLGRLKTGTPARLAKESIDFSALEVQKGDALPVPMSFLNETVSVEPTKQLDCFGTHTTPQM 292

  Fly   284 SDIVRDNLHVNRHVTE-EITGPRYCPSIESKILRF-GAKVHQVWLEPEGLDSSLVYPQGISCTLP 346
            .|.:|:|||.:.|:.: .|.|||||||||:||||| ....|::||||||.:|.::||.|||.::|
Yeast   293 HDFLRNNLHQSIHIQDTTIKGPRYCPSIEAKILRFPDRSSHKIWLEPEGFNSDVIYPNGISNSMP 357

  Fly   347 HDQQVELVHAIQGLEKAVVVQPGYGVEYDFIDPRELYPTLETKRVPGLFFAGQINGTTGYEEAAA 411
            .|.|::::..|.|:....::||.||||||::|||:|.|:||||.|.|||.|||||||||||||||
Yeast   358 EDVQLQMMRLIPGMANVEILQPAYGVEYDYVDPRQLKPSLETKLVDGLFLAGQINGTTGYEEAAA 422

  Fly   412 QGIIAGANAAGKTRHSDGRQLTISRTEGYIGVLIDDLTSLGTNEPYRMFTSRAEFRLSLRPDNAD 476
            ||||||.| ||.....:..||.:.|:|.|||||||||.:.|..|||||||||:|||:|:|.||||
Yeast   423 QGIIAGIN-AGLLSRQEREQLVLKRSEAYIGVLIDDLINNGVIEPYRMFTSRSEFRISVRADNAD 486

  Fly   477 MRLTQKGYEFGLVSSDRYQHFQQTEARLQSAIESLRRLRKHTHYWRQALNLPKAKASVEKSAFDM 541
            .|||..|.:.|::|..|...:.:.:......|.:|:..:..:..|...|....|..:..:||:::
Yeast   487 FRLTPIGAQLGIISPVRLSQYSRDKHLYDETIRALQNFKLSSQKWSSLLQANIAPQAENRSAWEI 551

  Fly   542 LGIPADNITIEQLIHLHPN-ELSWLKGERNLAERLKIEALYSFFVDEQQRDVEDVRREERLSIPA 605
            ...  .::.:.:|....|: .::.|....::..::.|:..|..::.:|.:.|:..:.:|.:.:|.
Yeast   552 FRF--KDMDLHKLYECIPDLPINLLDIPMHVVTKINIQGKYEPYIVKQNQFVKAFQADENMLLPQ 614

  Fly   606 DIDYFSKSL-SLSNEERQKLTLIQPQTIAAASRIQGVTPSTIVRILKYVKK 655
            |.||  :.| :||.|.:..|..:||.||..|.||||:|.:.:..:.:..:|
Yeast   615 DYDY--RQLPTLSTECKLLLNRVQPLTIGQARRIQGITAAALFELYRVARK 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4610	NP_611677.1	MnmG	28..661	CDD:440214	286/636 (45%)
MTO1	NP_011278.2	gidA	37..665	CDD:272927	286/636 (45%)