Protein Alignment CG4610 and Mto1

DIOPT Version :10

• Sequence 1: NP_611677.1
• Gene: CG4610 / 37571
• FlyBaseID: FBgn0034735
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_080934.2
• Gene: Mto1 / 68291
• MGIID: 1915541
• Length: 669
• Species: Mus musculus
• Alignment Length: 670
• Identity: 369/670 - (55%)
• Similarity: 489/670 - (72%)
• Gaps: 33/670 - (4%)

  Fly    12 WA----------RRIRAPSR---SAHSAGADIYDVVVIGGGHAGTEASAAAARMGSRTLLLTHKL 63
            ||          ||:|:.|.   :.|      :||||||||||||||:|||||.|||||||||::
Mouse    10 WAAASLGRRLPLRRLRSDSAAPCTPH------FDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRV 68

  Fly    64 ETIGEMSCNPSFGGIGKGHLMREVDALDGVCARCCDVSGVHYKVLNRRRGPAVWGPRAQIDRQLY 128
            :|||:||||||||||||||||||||||||:|:|.||.||:||||||||:||||||.||||||:||
Mouse    69 DTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRICDQSGIHYKVLNRRKGPAVWGLRAQIDRKLY 133

  Fly   129 KKAVQQELHSTPNLEIRAAAVDNL-LIEDEQDTQAR-RCTGVLLANGEVVRSRSVVLTTGTFLRA 191
            |:.:|:|:.|||.|.::..||::| |.|.|.....: |..||:||:|..:.:.||:||||||||.
Mouse   134 KQNMQKEILSTPLLTVQKGAVEDLVLAEPEPGYPGKSRVRGVVLADGSTIYAESVILTTGTFLRG 198

  Fly   192 HINIGLEVRPAGRIGDAPAKALGEAIDRLGFRMGRLKTGTPPRIAKDSVDFSQLQRHEGDDPPMP 256
            .|.||||:.||||:||.|:..|.:.:::|||.:||||||||||:||:|::||.|.:|..|||.:|
Mouse   199 MIIIGLEMHPAGRLGDQPSIGLAQTLEKLGFMVGRLKTGTPPRLAKESINFSILNKHTPDDPSIP 263

  Fly   257 FSFLNKDVWLPAKDQLPCYLTYTTPKVSDIVRDNLHVNRHVTEEITGPRYCPSIESKILRFGAKV 321
            ||||:..||:..:||||||||:|.|:|..||.:|||:|.||.|...|||||||||||:|||..::
Mouse   264 FSFLSDSVWIKPEDQLPCYLTHTNPRVDAIVLENLHLNSHVQETTKGPRYCPSIESKVLRFPNRL 328

  Fly   322 HQVWLEPEGLDSSLVYPQGISCTLPHDQQVELVHAIQGLEKAVVVQPGYGVEYDFIDPRELYPTL 386
            |||||||||:||.|:||||:|.|||.:.|.:::..|:|||||.:|.|||||:||::|||::.|:|
Mouse   329 HQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMVHPGYGVQYDYLDPRQISPSL 393

  Fly   387 ETKRVPGLFFAGQINGTTGYEEAAAQGIIAGANAAGKTRHSDGRQLTISRTEGYIGVLIDDLTSL 451
            ||..|..||||||||||||||||||||:|||.||:  .|.|......:|||||||||||||||:|
Mouse   394 ETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINAS--LRVSRKPPFVVSRTEGYIGVLIDDLTTL 456

  Fly   452 GTNEPYRMFTSRAEFRLSLRPDNADMRLTQKGY-EFGLVSSDRYQHFQQTEARLQSAIESLRRLR 515
            ||:|||||||||.||||||||||||.|||.:.: |.|.|||.|::.....::.|:..|..|:.::
Mouse   457 GTSEPYRMFTSRVEFRLSLRPDNADTRLTFRAHKEAGCVSSQRFERALWMKSSLEEGISVLKSIK 521

  Fly   516 KHTHYWRQALNLPKAKASVEK----SAFDMLGIPADNITIEQLIHLHPNELSWLKGERNLAERLK 576
            ..:..|::.  :|:...|:.:    ||.|:|  ..:.:.:|.|:.:.|..|......|.||.|||
Mouse   522 FSSSKWKKL--IPQIPISINRSLPVSALDVL--KYEEVDMESLVGVLPEPLEKYTACRELARRLK 582

  Fly   577 IEALYSFFVDEQQRDVEDVRREERLSIPADIDYFS-KSLSLSNEERQKLTLIQPQTIAAASRIQG 640
            |||.|...:..|.:::::|:::|.|.:|.::||.: :.:|||.|.|:||.|.:||||.|||||.|
Mouse   583 IEASYESVLSYQLQEIKEVQQDEALQLPHELDYLTIRDVSLSQEVREKLHLSRPQTIGAASRIPG 647

  Fly   641 VTPSTIVRILKYVKKAELAK 660
            |||:.|:.:|::|:....::
Mouse   648 VTPAAIINLLRFVRSTRQSR 667

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4610	NP_611677.1	MnmG	28..661	CDD:440214	362/641 (56%)
Mto1	NP_080934.2	MnmG	56..669	CDD:440214	344/618 (56%)