Protein Alignment CG4610 and Mto1

DIOPT Version :10

• Sequence 1: NP_611677.1
• Gene: CG4610 / 37571
• FlyBaseID: FBgn0034735
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_001100311.1
• Gene: Mto1 / 300852
• RGDID: 1308830
• Length: 679
• Species: Rattus norvegicus
• Alignment Length: 667
• Identity: 371/667 - (55%)
• Similarity: 489/667 - (73%)
• Gaps: 33/667 - (4%)

  Fly    12 WA----------RRIRAPSR---SAHSAGADIYDVVVIGGGHAGTEASAAAARMGSRTLLLTHKL 63
            ||          ||:|:.|.   |.|      :||||||||||||||:|||||.|||||||||::
  Rat    10 WASASLGRRLPLRRLRSDSAAPCSPH------FDVVVIGGGHAGTEAAAAAARCGSRTLLLTHRV 68

  Fly    64 ETIGEMSCNPSFGGIGKGHLMREVDALDGVCARCCDVSGVHYKVLNRRRGPAVWGPRAQIDRQLY 128
            :|||:||||||||||||||||||||||||:|:|.||.||:||||||||:||||||.||||||:||
  Rat    69 DTIGQMSCNPSFGGIGKGHLMREVDALDGLCSRVCDQSGIHYKVLNRRKGPAVWGLRAQIDRKLY 133

  Fly   129 KKAVQQELHSTPNLEIRAAAVDNLLIEDEQDTQA--RRCTGVLLANGEVVRSRSVVLTTGTFLRA 191
            |:.:|:|:.|||.|.::..||::|::.:.:....  .|..||:||:|..:.:.|||||||||||.
  Rat   134 KQNMQKEILSTPLLTVQEGAVEDLVLAEPEPGYGGKSRVRGVVLADGSTMHAESVVLTTGTFLRG 198

  Fly   192 HINIGLEVRPAGRIGDAPAKALGEAIDRLGFRMGRLKTGTPPRIAKDSVDFSQLQRHEGDDPPMP 256
            .:.|||||.||||:||.|:..|.:.:::|||.:||||||||||:||:|::||.|..|..|:||:|
  Rat   199 ALIIGLEVHPAGRLGDQPSIGLAQTLEKLGFMVGRLKTGTPPRLAKESINFSILHEHTADNPPIP 263

  Fly   257 FSFLNKDVWLPAKDQLPCYLTYTTPKVSDIVRDNLHVNRHVTEEITGPRYCPSIESKILRFGAKV 321
            ||||:.|||:..:||||||||:|.|:|.::|.:|||:|.||.|...|||||||||||:|||..::
  Rat   264 FSFLSDDVWIKPEDQLPCYLTHTNPRVDELVLENLHLNSHVKETTRGPRYCPSIESKVLRFPNRL 328

  Fly   322 HQVWLEPEGLDSSLVYPQGISCTLPHDQQVELVHAIQGLEKAVVVQPGYGVEYDFIDPRELYPTL 386
            |||||||||:||.|:||||:|.|||.:.|.:::..|:|||||.:|.|||||:||::|||::.|:|
  Rat   329 HQVWLEPEGMDSDLIYPQGLSVTLPAELQEKMITCIRGLEKAKMVHPGYGVQYDYLDPRQISPSL 393

  Fly   387 ETKRVPGLFFAGQINGTTGYEEAAAQGIIAGANAAGKTRHSDGRQLTISRTEGYIGVLIDDLTSL 451
            ||..|..||||||||||||||||||||:|||.||:  .|.|......:|||||||||||||||:|
  Rat   394 ETHLVQRLFFAGQINGTTGYEEAAAQGVIAGINAS--LRVSRKPPFVVSRTEGYIGVLIDDLTTL 456

  Fly   452 GTNEPYRMFTSRAEFRLSLRPDNADMRLTQKGYE-FGLVSSDRYQHFQQTEARLQSAIESLRRLR 515
            ||:|||||||||.||||||||||||.|||.:.:| .|.||..||:.....::.|:..|..|:.::
  Rat   457 GTSEPYRMFTSRVEFRLSLRPDNADTRLTFRAHEDAGCVSPQRYKRALWMKSSLEEGISVLKSIK 521

  Fly   516 KHTHYWRQALNLPKAKASVEK----SAFDMLGIPADNITIEQLIHLHPNELSWLKGERNLAERLK 576
            ..:..|::.  :|:|..|:.:    ||.|:|  ..:.:.:|.|..:.|..|......|.||.|||
  Rat   522 FSSSKWKKL--IPQAPISINRSLPVSALDVL--KYEEVDMESLASVVPEPLKKYTACRELARRLK 582

  Fly   577 IEALYSFFVDEQQRDVEDVRREERLSIPADIDYFS-KSLSLSNEERQKLTLIQPQTIAAASRIQG 640
            |||.|...:..|.:::::|:::|.|.:|.|:||.: |.:|||.|.|:||.|.:||||.|||||.|
  Rat   583 IEATYESVLLYQLQEIKEVQQDEALQLPQDLDYLTIKDVSLSQEVREKLHLSRPQTIGAASRIPG 647

  Fly   641 VTPSTIVRILKYVKKAE 657
            |||:.|:.:|::|:..:
  Rat   648 VTPAAIINLLRFVRNTQ 664

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4610	NP_611677.1	MnmG	28..661	CDD:440214	363/638 (57%)
Mto1	NP_001100311.1	MnmG	56..669	CDD:440214	345/615 (56%)