Protein Alignment CG4610 and ips1

DIOPT Version :10

• Sequence 1: NP_611677.1
• Gene: CG4610 / 37571
• FlyBaseID: FBgn0034735
• Length: 661
• Species: Drosophila melanogaster
• Sequence 2: NP_595531.1
• Gene: ips1 / 2540415
• PomBaseID: SPBC30B4.06C
• Length: 666
• Species: Schizosaccharomyces pombe
• Alignment Length: 646
• Identity: 284/646 - (43%)
• Similarity: 404/646 - (62%)
• Gaps: 33/646 - (5%)

  Fly    32 DVVVIGGGHAGTEASAAAARMGSRTLLLTHKLETIGEMSCNPSFGGIGKGHLMREVDALDGVCAR 96
            :||||||||||.||:|||:|:|::|.|||...:.||:|||||:|||||||.||||:|||.||.:.
pombe    18 NVVVIGGGHAGVEAAAAASRLGAKTTLLTKSFDNIGQMSCNPAFGGIGKGTLMREIDALGGVVSG 82

  Fly    97 CCDVSGVHYKVLNRRRGPAVWGPRAQIDRQLYKKAVQQELHS-TPNLEIR--AAAVDNLLIEDEQ 158
            .||.|.:.:.:|||..|||||.||||:||.::||.:|:.:.: ..||::|  ||...|:|.||:
pombe    83 VCDESAIQFHMLNRSNGPAVWSPRAQMDRSVFKKNMQKTISTYRKNLQVREGAAVSINVLTEDD- 146

  Fly   159 DTQARRCTGVLLANGEVVRSRSVVLTTGTFLRAHINIGLEVRPAGRIGDAPAKALGEAIDRLGFR 223
              ..:.|..::|.:|..:.:..:|:||||||...||:||....|||.|:.|:..|.:.:..|||:
pombe   147 --GKQVCDSIVLEDGTAIPASCIVITTGTFLGGQINVGLTQLAAGRYGERPSLPLSKCLSNLGFK 209

  Fly   224 MGRLKTGTPPRIAKDSVDFSQLQRHEGDDPPMPFSFLN--KDVWLPAKDQLPCYLTYTTPKVSDI 286
            |||||||||||:: ..::.|::....||:.|..|||||  :| :.||..|..||.||||....:|
pombe   210 MGRLKTGTPPRLS-SPINISKMTEQTGDEIPETFSFLNLERD-FSPALPQRSCYRTYTTELTHEI 272

  Fly   287 VRDNLHVNRH-VTEEITGPRYCPSIESKILRFGAKV-HQVWLEPEGLD-SSLVYPQGISCTLPHD 348
            ||.||....| :..:|..||||||:|:|:.||..|. |.:|||||||| :|..||.|:|.::|.:
pombe   273 VRKNLAFAPHMLAGDILSPRYCPSLEAKVTRFPHKARHLIWLEPEGLDPNSWWYPNGLSNSMPEE 337

  Fly   349 QQVELVHAIQGLEKAVVVQPGYGVEYDFIDPRELYPTLETKRVPGLFFAGQINGTTGYEEAAAQG 413
            .|..::.:|.|||...:|:|.|||.||::.|.:|..|||||::.||:.|||||||||||||||||
pombe   338 IQHNIIRSIPGLENCNIVRPAYGVMYDYVIPTQLKATLETKKIQGLYLAGQINGTTGYEEAAAQG 402

  Fly   414 IIAGANAAGKTRHSDGRQ-LTISRTEGYIGVLIDDLTSLGTNEPYRMFTSRAEFRLSLRPDNADM 477
            |:||.||.   ..:.||: :.|.|....:||::|||.:.|..||||:||||:|:||:.|.||||:
pombe   403 ILAGLNAG---LSALGREPVDIPRNTALLGVMVDDLITKGVKEPYRVFTSRSEYRLTTRADNADL 464

  Fly   478 RLTQKGYEFGLVSSD-RYQHFQQTEARLQSAIESLRRLRKHTHYWRQALNLPKAKASVEKSAFDM 541
            |||......||:... .::.||:|::.|..:.:..:........|.: |.:|.......:||:|:
pombe   465 RLTPLAQSIGLLDDQTHWESFQRTKSLLDFSNKIAKEFILSPQQWSK-LGMPIPNDGKYRSAWDL 528

  Fly   542 LGIPADNITIEQLIHLHPNELSWLKG-ERNLAERLKIEALYSFFVDEQQRDVEDVR-REERLSIP 604
            |..  .|:.:..:|...|.    ||. .:.:.:||.||..|::::..|....:.:. |:|...||
pombe   529 LSF--TNLDLFCVISCIPK----LKDIPKRVLQRLIIEGKYTYYIKRQGTQNKQLNCRDESTVIP 587

  Fly   605 ADIDYFSKSLSLSNEERQKLTLIQPQTIAAASRIQGVTPSTIVRILKY-----VKKAELAK 660
            :|.| |....|:|.||...|..|:|.||....||||:.|.||:|:|::     .|:|.|.|
pombe   588 SDFD-FDTLHSVSAEELMLLKTIRPATIGQLKRIQGIKPGTIIRLLRHTYYNPAKEAWLRK 647

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4610	NP_611677.1	MnmG	28..661	CDD:440214	284/646 (44%)
ips1	NP_595531.1	MnmG	36..634	CDD:440214	265/613 (43%)