Protein Alignment CG10384 and SF1

DIOPT Version :10

• Sequence 1: NP_611673.3
• Gene: CG10384 / 37567
• FlyBaseID: FBgn0034731
• Length: 492
• Species: Drosophila melanogaster
• Sequence 2: NP_001365886.1
• Gene: SF1 / 7536
• HGNCID: 12950
• Length: 764
• Species: Homo sapiens
• Alignment Length: 516
• Identity: 109/516 - (21%)
• Similarity: 172/516 - (33%)
• Gaps: 171/516 - (33%)

  Fly    10 LEERSLKGSEKL---------KMLDITRD-------KP--VKVAVKVAVPVRDHPKFNFVGKLLG 56
            |..|..:..:||         :|:.:..|       ||  .:|:.||.:|..::|:.||||.|:|
Human   219 LNTREFRTRKKLEEERHNLITEMVALNPDFKPPADYKPPATRVSDKVMIPQDEYPEINFVGLLIG 283

  Fly    57 PKGNSMKRLQEDTMCKMAVLGRGSMRD---RRKEEELRGSGDSRYAHLFEDLHVEISTFAAPAEA 118
            |:||::|.::::...|:.:.|:||:::   .||:.::....|       |.||..::     |..
Human   284 PRGNTLKNIEKECNAKIMIRGKGSVKEGKVGRKDGQMLPGED-------EPLHALVT-----ANT 336

  Fly   119 HARIAYALAEVRRFL-----VPDYHDDIRQEQMWEMQALTSTPALGAHSLEDSHSPTIN--SSSQ 176
            ...:..|:.::|..|     .|:..:|:|:.|:.|:..|..|       |.:..:..:.  .||:
Human   337 MENVKKAVEQIRNILKQGIETPEDQNDLRKMQLRELARLNGT-------LREDDNRILRPWQSSE 394

  Fly   177 VGGTTNSSSNGASGRGLGGGLADMDTSNDDKSDDASGM-------ECLSAVDKLDCSSSCASLG- 233
            ....||::.....|   |.|....|.......|..|..       |.||.:.:|..:...||:|
Human   395 TRSITNTTVCTKCG---GAGHIASDCKFQRPGDPQSAQDKARMDKEYLSLMAELGEAPVPASVGS 456

  Fly   234 ISGITT---------------------ISTTSPEHP----HPHQHHQQHQQH--------QQHHA 265
            .||..|                     :|||....|    .|.:....|..|        ...|:
Human   457 TSGPATTPLASAPRPAAPANNPPPPSLMSTTQSRPPWMNSGPSESRPYHGMHGGGPGGPGGGPHS 521

  Fly   266 HLHP----AHAHGNQQQQ------------------QQVQHHHSHQAHFHQLLQQAHGGASAAAA 308
            ..||    ...||....|                  .|..|...|  |....:.|..|.....:.
Human   522 FPHPLPSLTGGHGGHPMQHNPNGPPPPWMQPPPPPMNQGPHPPGH--HGPPPMDQYLGSTPVGSG 584

  Fly   309 ACGEHL--------------------SGQTTPATAAAL-----------------HTTAMAVALQ 336
            ....|.                    |||..|..:..|                 .:.|.:..|.
Human   585 VYRLHQGKGMMPPPPMGMMPPPPPPPSGQPPPPPSGPLPPWQQQQQQPPPPPPPSSSMASSTPLP 649

  Fly   337 HQ------LTAAGIGGLLKPATGVGATMAGLPTTQAGAAALQLPGDGESSGSTLTLLEPPG 391
            .|      .|:||.|.:  |           |..|..|||...||..:..|:...:..|||
Human   650 WQQNTTTTTTSAGTGSI--P-----------PWQQQQAAAAASPGAPQMQGNPTMVPLPPG 697

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10384	NP_611673.3	KH-I_KHDRBS	43..131	CDD:411812	23/90 (26%)
SF1	NP_001365886.1	MSL5	142..382	CDD:227503	45/181 (25%)
		ZnF_C2HC	403..418	CDD:197667	4/17 (24%)