DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10384 and Khdrbs3

DIOPT Version :9

Sequence 1:	NP_001163254.2	Gene:	CG10384 / 37567	FlyBaseID:	FBgn0034731	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_071585.2	Gene:	Khdrbs3 / 64015	RGDID:	620921	Length:	346	Species:	Rattus norvegicus

Alignment Length:	186	Identity:	90/186 - (48%)
Similarity:	126/186 - (67%)	Gaps:	11/186 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 ERSLKGSEK--LKMLDITRDKPVKVAVKVAVPVRDHPKFNFVGKLLGPKGNSMKRLQEDTMCKMA 74
            |:..||..|  .|.:|:..:|.:|:..||.:||:..||||||||||||:|||:|||||:|:.||:
  Rat    32 EKFQKGEAKDEEKYIDVVINKNMKLGQKVLIPVKQFPKFNFVGKLLGPRGNSLKRLQEETLTKMS 96

  Fly    75 VLGRGSMRDRRKEEELRGSGDSRYAHLFEDLHVEISTFAAPAEAHARIAYALAEVRRFLVPDYHD 139
            :||:|||||:.||||||.||:::|.||.:||||.|..||.||||:||:.:||.|:::||:|||:|
  Rat    97 ILGKGSMRDKAKEEELRKSGEAKYFHLNDDLHVLIEVFAPPAEAYARMGHALEEIKKFLIPDYND 161

  Fly   140 DIRQEQMWEMQALTSTPALGAHSLEDSHSPTINSSSQVGGTTNSSSNGASGRGLGG 195
            :|||.|:.|:..|..       ..|::..|.:...|.:  .|...:..|..||.||
  Rat   162 EIRQAQLQELTYLNG-------GSENADVPVVRGKSTL--RTRGVTTPAITRGRGG 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10384	NP_001163254.2	SF1_like-KH	44..155	CDD:239088	69/110 (63%)
Khdrbs3	NP_071585.2	Involved in homodimerization. /evidence=ECO:0000250\|UniProtKB:O75525	1..160		73/127 (57%)
		Qua1	4..53	CDD:406639	6/20 (30%)
		KH-I_KHDRBS3	48..160	CDD:411898	67/111 (60%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..268
		Sam68-YY	266..320	CDD:406871
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	320..346
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348926
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012406at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950