DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10384 and Khdrbs2

DIOPT Version :9

Sequence 1:	NP_001163254.2	Gene:	CG10384 / 37567	FlyBaseID:	FBgn0034731	Length:	492	Species:	Drosophila melanogaster
Sequence 2:	NP_579852.1	Gene:	Khdrbs2 / 170843	RGDID:	621738	Length:	349	Species:	Rattus norvegicus

Alignment Length:	195	Identity:	89/195 - (45%)
Similarity:	125/195 - (64%)	Gaps:	35/195 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LSALEERSLKGS------EKLKMLDITRDKPVKVAVKVAVPVRDHPKFNFVGKLLGPKGNSMKRL 65
            |.|.|....:||      |:.|.||:..:|.:|::.:|.:||:.:||||||||||||:|||:|||
  Rat    27 LLAEEIEKFQGSDGRKEDEEKKYLDVISNKNIKLSERVLIPVKQYPKFNFVGKLLGPRGNSLKRL 91

  Fly    66 QEDTMCKMAVLGRGSMRDRRKEEELRGSGDSRYAHLFEDLHVEISTFAAPAEAHARIAYALAEVR 130
            ||:|..||::||:|||||:.||||||.||:::||||.::|||.|..||.|.||::|:::||.|::
  Rat    92 QEETGAKMSILGKGSMRDKAKEEELRKSGEAKYAHLSDELHVLIEVFAPPGEAYSRMSHALEEIK 156

  Fly   131 RFLVPDYHDDIRQEQMWEMQALTSTPALGAHSLEDSHSPTINSSSQVGGTTNSSSNGASGRGLGG 195
            :||||||:|:|||||:.|:..|                             |.|.....|||:.|
  Rat   157 KFLVPDYNDEIRQEQLRELSYL-----------------------------NGSEESGRGRGIRG 192

Fly 196 195
Rat 193 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10384	NP_001163254.2	SF1_like-KH	44..155	CDD:239088	69/110 (63%)
Khdrbs2	NP_579852.1	Qua1	6..57	CDD:292891	9/29 (31%)
		SF1_like-KH	61..180	CDD:239088	72/147 (49%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..263		5/12 (42%)
		Sam68-YY	271..321	CDD:293176
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	320..349
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166348934
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1012406at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.950