Protein Alignment ppk12 and scnn1b

DIOPT Version :10

• Sequence 1: NP_611672.1
• Gene: ppk12 / 37566
• FlyBaseID: FBgn0034730
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 673
• Identity: 144/673 - (21%)
• Similarity: 229/673 - (34%)
• Gaps: 221/673 - (32%)

  Fly    18 LLKSFVRSLRQ---------------FLNQTSLHGLKFV---GDSGLSSWERSFFLGSFVTALII 64
            |.:.|.|:|.:               |.:.|:.||.|.:   |......|            .|:
 Frog     9 LKRYFTRALHRIQKGPGYTYKELLVWFCDNTNTHGPKRIIKEGPKKRVMW------------FIL 61

  Fly    65 TVHLISNIYVKWD---STPVIIGISPQATSILK-VPFPAITICNMNQVQRS-----------LVA 114
            |:.....::.:|.   .|.:..|:|...:...| :.|||:|:||.|..:.|           |||
 Frog    62 TLVFAGLVFWQWGVLILTYLSYGVSVSLSIGFKTMEFPAVTVCNANPYKYSRVKPLLKDLDALVA 126

  Fly   115 NYRE----GSNESALLKLLCESDSWESSEAD------------EEFSASNFVTNNL--------- 154
            ...:    .|.:.|  ....:|.:.::...|            :|...||.:.||:
 Frog   127 TALDRIQFSSQDQA--NTFTQSSTNQNVTLDPTLWNHIPLVVIDETDPSNPIVNNIFDNNAIYSK 189

  Fly   155 -----KISEFVSNHSQSCERMLLFC---RFSAVERN---------------CSQLFQQI------ 190
                 ..||..:::||..:..:..|   ....|.||               .|.:|..:
 Frog   190 NNSFRNSSEDQTSYSQRYKVAMKLCTNNNTQCVYRNFTSGIQALQEWYLLQLSSIFSNVPLADRI 254

  Fly   191 -----LTDEGLCCVFNFQPPEYLYKPFANNNRNLTNSDGFESVMWDPESGYPEQLPPKFY----- 245
                 ..|..|.|:|..||..|         ||.|.       ::|.:.|       ..|
 Frog   255 AMGFKAEDLILTCLFGGQPCSY---------RNFTR-------IYDADYG-------NCYIFNWG 296

  Fly   246 -----PATASGTGITLGFTAVLDAEMGEY--YCSSTNGPGFKVYFHNPIEVPKVKEAGLISAIGY 303
                 |..::..|...|...|||.|.|||  |..:|  ...::..|.....|.||:.|:.:..|.
 Frog   297 QEGEDPMASANPGADFGLKLVLDIEQGEYLPYVQTT--AAARLILHQQRSFPFVKDLGIYAMPGT 359

  Fly   304 ETNYRIEMVRAEAVPAIRSISRDGRQCLFKNEKELIFYRIYTRLN-------CENECLAAFLYDT 361
            ||:..:.:.:.|.:.|..|      .|.. |..::....:|...|       |...|....:..|
 Frog   360 ETSIAVLVDQLEHMEAPYS------SCTV-NGSDIPVQNLYAEFNSSYSIQSCLRSCYQEQMVQT 417

  Fly   362 CSCIPFDHPLIYSNASICSMGDTSCVRRAQRASNRPGWAKC----------RQQCL----PSCFD 412
            |.|..:.:|| .:.:..||            ....|.|..|          |:.|:    ..|.|
 Frog   418 CGCADYQYPL-PNGSEYCS------------NDKYPDWVPCYYGLRDSVADRESCISLCQQPCND 469

  Fly   413 LNY--LASGFSFPLASNNFQLANALVESFNKSYLSKNIAV-------INVYFRESVYYGNTKNAY 468
            ..|  :.|...:|.|.....:.:.|  |:.|. .|.||.|       :|:||:|..|...|::..
 Frog   470 TQYKMVISMADWPSAGAQDWIFHVL--SYEKD-SSHNITVNRNGIVRLNIYFQEFNYRSITESEA 531

  Fly   469 VGLTEFLSNVGGVMGLFMGFSVISLAEI-------LYFLILKPLAELFVW--------KRSSHVD 518
            ..:...|||:||..|.:||.||:.:.|.       ::..|||.||    |        :|:.:.|
 Frog   532 TNVVWLLSNLGGQFGFWMGGSVLCIIEFGEIIIDCVWITILKLLA----WIKDRRQRRQRAQYAD 592

  Fly   519 SEKSLKHNAFGIEKGQSSDNPSF 541
            ...::.      |..::..||.|
 Frog   593 PPPTVS------ELVEAHTNPGF 609

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	ASC	29..499	CDD:459966	128/595 (22%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	140/655 (21%)