DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk12 and ppk30

DIOPT Version :9

Sequence 1:	NP_611672.1	Gene:	ppk12 / 37566	FlyBaseID:	FBgn0034730	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	NP_001263076.1	Gene:	ppk30 / 43487	FlyBaseID:	FBgn0039677	Length:	457	Species:	Drosophila melanogaster

Alignment Length:	518	Identity:	106/518 - (20%)
Similarity:	180/518 - (34%)	Gaps:	156/518 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 LKFVGDSGLSSWERSFFLGSFVTALIITVH--LISN--IYVKWDSTPVIIGISPQATSILKVPFP 98
            ||..|..|.:|..|...:...:.|.:.||:  ::|:  .:..|..|    .|......:.::.||
  Fly    26 LKKEGAGGWASTRRYARIPLKIMAALATVYVSILSSERYFYYWVQT----SIERTDMHVSEIDFP 86

  Fly    99 AITICNMNQVQRSLVANYREGSNESALLKL--------LCESDSWESSEA----DEEFSASNFVT 151
            |:||..:|                .::||.        |.:|..|::..:    ||.|:
  Fly    87 AVTIIPIN----------------LSILKAEKLSKAYNLVQSVVWQTPMSARLTDENFT------ 129

  Fly   152 NNLKISEFVSNHSQS----------CERMLLFCRFSAVERNCSQLFQQILTDEGLCCVFNFQPPE 206
               :.||..:.::||          |:.....|::.....||..||:...|..|....||
  Fly   130 ---EFSELENWNAQSWGIYQALQMNCQHFFTECQWRRKAMNCCDLFRPTKTFNGFAFEFN----- 186

  Fly   207 YLYKPFANNNRNLTNSDGFESVMWDPESGYPEQLPPKFYPATASGTGITLGFTAVLDAEMGEYYC 271
                       :|.:|...|:                 :|.:.:..|...|....:..:.| .|.
  Fly   187 -----------SLVSSGRDET-----------------WPWSVASCGSYSGLNVKIKRQQG-LYT 222

  Fly   272 SSTNGPGFKVYFHNPIEVPKVKEAGLISAIGYETNYRI----EMVRAEAVPAIRSISRDGRQCLF 332
            .:|.|    |..|.|.::       |..:|.|.:..||    |.:...|...:|:.....|:|.|
  Fly   223 LNTMG----VIVHEPTQL-------LGMSIDYSSEDRIVVPVEPLHFTAELDVRARPVQMRRCYF 276

  Fly   333 KNEKELIFYRIYT---RLNCENECLAAFLYDTCSC---IPFDHPLIYSNAS---------ICSMG 382
            :||       |.|   |..|..:|...::...|:|   :|........|.:         ||.:.
  Fly   277 ENE-------IPTGKSRSECIYKCHVNYIISKCNCSLELPVKATQDEDNIAAAKESNGRRICGVK 334

  Fly   383 DTSCVRR------------AQRASNRPGWAKCRQQCLPSCFDLNYLASGFSFPLASNNFQLANAL 435
            |.:|..:            .:...|......|  .|.|.|....|..|.::..::::. .||.|:
  Fly   335 DLACFNQHRLSLFSMSNIIEESRDNVFSTVDC--GCFPQCGHTQYHTSTYTEKMSAHT-NLAAAI 396

  Fly   436 VESFNKSYLSKNIAVINVYFRESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVIS-LAEIL 497
                          .|:|||:|...:.........|.:.:.:.||:.||.||.||:. :.|:|
  Fly   397 --------------EIDVYFQEETLFSYRSMLRFTLIDLMVSYGGIAGLIMGISVLGCINELL 445

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	106/518 (20%)
ppk12	NP_611672.1	ASC	29..499	CDD:279230	106/518 (20%)
ppk30	NP_001263076.1	ASC	47..446	CDD:279230	100/497 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920