Protein Alignment ppk12 and asic1b

DIOPT Version :9

• Sequence 1: NP_611672.1
• Gene: ppk12 / 37566
• FlyBaseID: FBgn0034730
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_999956.1
• Gene: asic1b / 407672
• ZFINID: ZDB-GENE-040513-1
• Length: 557
• Species: Danio rerio
• Alignment Length: 587
• Identity: 131/587 - (22%)
• Similarity: 209/587 - (35%)
• Gaps: 172/587 - (29%)

  Fly    25 SLRQFLNQTSLHGLK--FVGDSGLS----SWERSFFLGSFVTALIITVHLISNIYVKWDSTPVII 83
            ||..|....||||..  ||.|...|    .|...|.|...:..|.:...:|  .|:::|...::
Zfish    65 SLATFFGGCSLHGANHVFVEDKKFSIRQGLWALVFLLAISMFLLQVVDRVI--YYLQYDYVTLL- 126

  Fly    84 GISPQATSILKVPFPAITICNMNQVQRSLVANYREGSNESALL---KLLCESDSWE-----SSEA 140
                ...:...:.|||||:||.|..:||.:       :.|.||   .||...|:..     :.|.
Zfish   127 ----DERNAKNMTFPAITLCNYNTFRRSQL-------SYSDLLFMGPLLGYEDNMAPGIPLAPEP 180

  Fly   141 DEEFSASNFVTNNLKISEFVSNHSQSCERMLLFCRFSAVERNC-SQLFQQILTDEGLCCVFNFQP 204
            |.:.|       ...::||.:......:.|||.|.|:..|  | ::.:::|.|..|.|..||
Zfish   181 DRQGS-------RFSLAEFFNRTRHRMDDMLLECNFAGKE--CGAEHWREIFTRYGKCYTFN--- 233

  Fly   205 PEYLYKPFANNNRNLTNSDGFESVMWDPESGYPEQLPPKFYPATASGTGITLGFTAVLDAEMGEY 269
                           :..||...::                  |..| |:..|...:||.:..||
Zfish   234 ---------------SGQDGRPLLI------------------TTKG-GMGNGLEIMLDIQQDEY 264

  Fly   270 Y------CSSTNGPGFKVYFHNPIEVPKVKEAGLISAIGYETNYRIEMVRAEAVP------AIRS 322
            .      ..:|...|.||..|...|.|.:.:.|...|.|::|....:..|...:|      ....
Zfish   265 LPVWGETDETTFEAGIKVQIHTQDEPPFIDQLGFGVAPGFQTFVSCQEQRLTYLPPPWGDCKATP 329

  Fly   323 ISRDGRQCLFKNEKELIFYRIYTRLNCENECLAAFLYDTCSC----IPFDHPLIYSNASICSMGD 383
            |..|             |:..|:...|..:|...:|.:.|:|    :|.|.|.
Zfish   330 IDSD-------------FFNTYSITACRIDCETRYLVENCNCRMVHMPGDAPY------------ 369

  Fly   384 TSCVRRAQRASNRPG----------WAKCRQQC-------------LPSCFDLNYLASGFSFPLA 425
              |.....:....|.          :..|...|             :||.....|||
Zfish   370 --CTPEQYKECADPALDFLVERDNDYCVCETPCNMTRYGKELSFVRIPSKASAKYLA-------- 424

  Fly   426 SNNFQLANALVESFNKS--YLSKNIAVINVYFRESVYYG--NTKNAYVGLTEFLSNVGGVMGLFM 486
                       :.:||:  |:|.||.|::::| |::.|.  ..|.|| .|...|.::||.||||:
Zfish   425 -----------KKYNKTEQYISDNIMVLDIFF-EALNYETIEQKKAY-ELAGLLGDIGGQMGLFI 476

  Fly   487 GFSVISLAEI---LYFLILKPLAELFVWKRSSHVDSEKSLKHNAFGIEKGQSSDN---PSFWHSK 545
            |.|::::.|:   ||.:|...|......|.....::|:....:...:::....||   ||.:.:.
Zfish   477 GASILTILELFDYLYEVIKFKLCRCAKKKHQRSNNNERGAVLSLDDVKRHAPCDNLRTPSTYPAN 541

  Fly   546 EL 547
            .|
Zfish   542 ML 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	119/531 (22%)
		ASC	29..499	CDD:279230	119/530 (22%)
asic1b	NP_999956.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..57
		ASC	66..548	CDD:295594	130/586 (22%)
		Selectivity filter. /evidence=ECO:0000305	477..479		1/1 (100%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170586647
Domainoid	1	1.000	101	1.000	Domainoid score	I6864
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	102	1.000	Inparanoid score	I4956
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	8	7.900