DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk12 and ppk16

DIOPT Version :9

Sequence 1:	NP_611672.1	Gene:	ppk12 / 37566	FlyBaseID:	FBgn0034730	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	NP_001334673.1	Gene:	ppk16 / 3885612	FlyBaseID:	FBgn0065108	Length:	531	Species:	Drosophila melanogaster

Alignment Length:	515	Identity:	134/515 - (26%)
Similarity:	228/515 - (44%)	Gaps:	73/515 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 FVRSLRQFLNQTSLHGLKFVGDSGLSSWERSFFLGSFVTALIITVHLISNIYVKW---DSTPVII 83
            |..::|.:...|||||..::....:|..||.|:|...:.|:|.::.|   :.|.|   ..||.:.
  Fly    52 FTENMRNYCQTTSLHGFSYITRQDISRHERWFWLVVVILAIITSIVL---VVVSWYWSQETPTVT 113

  Fly    84 GISPQATSILKVPFPAITICNMNQVQRSLVANYRE------GSNESALLKL----LCESDSWESS 138
            .|.........:||||:||||.|::.:|...:..:      |.|.|.|..|    |...|:..|:
  Fly   114 VIESSHFPTWNIPFPAVTICNFNKISKSKALSLLDQMQVPVGINRSELHNLFNLTLLPVDTMISN 178

  Fly   139 EADEEFSASNFVTNNLKISEFVSNHSQSCERMLLFCRFSAVERNCSQLFQQILTDEGLCCVFNFQ 203
            ::.:::... ...|||.::......|..|..|:..|.:..:...|..|||:|.|.||.||.||:
  Fly   179 DSLQKYDRI-LSLNNLTLNRLTQQLSPDCIEMISSCIWKGINTRCESLFQRIDTMEGQCCTFNY- 241

  Fly   204 PPEYLYKPFANNNRNLTNSDGFESVMWDPESGYPE----QLPPKFYPATASGTGITLGFTAVLDA 264
                 :...:||                    :||    |:|.:.|..|  |.|...|.:.:|:.
  Fly   242 -----FGGISNN--------------------FPEKIAYQVPKRPYRVT--GCGYPTGLSVLLNP 279

  Fly   265 EMGEYYCSSTNGPGFKVYFHNPIEVPKVKEAGLISAIGYETNYRIEMVRAEAVPAIRSISRDGRQ 329
            .:.:||.:..:|.||::..|:....|.......:.....|:..||......|...||.:....|.
  Fly   280 MISDYYGTFFSGFGFRLLLHDAYNFPDENSETKVVTTTRESFVRINPESTYATNDIRRMDLSLRN 344

  Fly   330 CLFKNEKELIFYRIYTRLNCENECLAAFLYDTCSCIPFDHPLIYSNAS--ICSMGDTSCVRRAQR 392
            |||.:|..:...|.|:.:||..||......|.|.|:|   |.:|:|.|  :|.:..|:|:..::|
  Fly   345 CLFGSEMTMHGLRRYSFINCMFECRVRMTVDLCGCLP---PYVYNNGSYKVCGVLQTNCIIHSKR 406

  Fly   393 ------ASNRPGWAKCRQQ------CLPSCFDLNYLASGFSFPLASNNFQLANALVESFNKSYLS 445
                  |:.....:..|:.      |||.|...:|::...:..|..:.|  ||.  .:||.   :
  Fly   407 LFSHALANLNFSLSIVRETDSFPCGCLPDCQSNHYVSESTTGRLDISYF--ANR--PTFNN---A 464

  Fly   446 KNIAVINVYFRESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISLAEILYFLILKPL 505
            .:..:::|:|.:.:......:.:......|::.||::||.||||:::..|.:|||..:|:
  Fly   465 TDRILLHVFFSDLMSTRYRTDIFQNWLSALASFGGLLGLIMGFSIVTAFEFIYFLTFRPV 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	128/501 (26%)
ppk12	NP_611672.1	ASC	29..499	CDD:279230	128/500 (26%)
ppk16	NP_001334673.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456738
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000867
OrthoInspector	1	1.000	-	-		otm24766
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
	9	8.740