DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk12 and ppk14

DIOPT Version :9

Sequence 1:	NP_611672.1	Gene:	ppk12 / 37566	FlyBaseID:	FBgn0034730	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	NP_609017.2	Gene:	ppk14 / 33887	FlyBaseID:	FBgn0031803	Length:	504	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	116/536 - (21%)
Similarity:	196/536 - (36%)	Gaps:	130/536 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    29 FLNQTSLHGLKFVGDSGLSSWERSFFLGSFVTALIITVHLISNIYVKWDSTPVIIGISPQATSIL 93
            :::::.:|||..:....:....|..:..:.:.|..:..|:...:..::.:......::....||.
  Fly    45 YISRSHIHGLYLLFLPSMRRRMRVLWALALICACTVLFHVSYLLGDRYHNKQFQTIVAHAHASIH 109

  Fly    94 KVPFPAITICNMNQVQRSLVANYRE-----GSNESALLKLLCESDSW---ESSEADEEFSASNFV 150
            .:.||.:.|||.|::..|.:...:.     .|.:....::|...|.:   :.:..|.....|...
  Fly   110 HIAFPVVIICNKNRLNWSRLPEIKSLYNITPSQDELFDRILTAYDGFSFHKFNAFDSLLGESLDE 174

  Fly   151 TNNLKISEFVSNHSQSCERMLLFCRFSAVERNCSQLFQQILTDEGLCCVFNFQPPEYLYKPFANN 215
            .|:|..:|.|...|..|:.:|..|.:....|:|.:||:......|.|..||
  Fly   175 LNHLNFTEIVIQMSWRCDEILRDCHWQTASRDCCKLFRPRRLPLGYCLAFN-------------- 225

  Fly   216 NRNLTNSDGFESVMWDPESGYPEQLPPKFYPATASGTGITLGFTAVLDAEMGEYYCSSTNGPGF- 279
              .|....|.|                         |||..|....|....|::...::...||
  Fly   226 --ELEKRRGTE-------------------------TGINTGLLLRLLLREGQHAPGNSGLKGFW 263

  Fly   280 ------KVYFHNPIE-VPKVKEAGLISAIGYETNYRIEMVRAEAVPAIRSISRDGRQCLFKNEKE 337
                  .|:|..||| ||..:           ||..:..|......:..|:....|.|:...|:|
  Fly   264 LTVVESSVWFGFPIEVVPHSR-----------TNVAVTAVYHYFDESTLSLPSSWRHCVMDYEEE 317

  Fly   338 LIFYRI-----YTRLNCENECLAAFLYDTCSCIPFDHPLIY--SNASICSMGDTSCVRRAQRASN 395
            ...:|.     |...||:.||...:|...|:|..   .|.|  ||...|.:.|..|:    .|.|
  Fly   318 SEHFRTLEGQKYMLENCQAECQQRYLLRYCNCTV---DLFYPPSNYPACRLKDLPCL----AAHN 375

  Fly   396 -------RPG----------WAKCRQQCLPSCFDLNYLASGFSFPLASNNFQLANALVESFNKSY 443
                   :||          ...|  :||.:|..|..|..                :.:|..:.:
  Fly   376 HLLQNFEQPGEHPYVHREESGLVC--ECLHNCKSLTLLTD----------------MRKSVQQPW 422

  Fly   444 LSKNIAVI-----NVYFRES---VYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISLAEILYFL 500
            |..|.:.|     ||||::.   ||..|....:|.|   :.:.||:..|.:|.|:|||.|.::|.
  Fly   423 LQPNSSAIESMWLNVYFKKPSMLVYKTNLIYTWVDL---IVSFGGICQLCLGCSIISLIEFVFFA 484

  Fly   501 ILKPLAELFVWKRSSH 516
            :.| :.:|: |:|.|:
  Fly   485 LYK-VPQLY-WERFSN 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	110/517 (21%)
ppk12	NP_611672.1	ASC	29..499	CDD:279230	110/517 (21%)
ppk14	NP_609017.2	ASC	45..483	CDD:279230	110/517 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm14782
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920