DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk12 and AgaP_AGAP009789

DIOPT Version :9

Sequence 1:	NP_611672.1	Gene:	ppk12 / 37566	FlyBaseID:	FBgn0034730	Length:	569	Species:	Drosophila melanogaster
Sequence 2:	XP_553643.3	Gene:	AgaP_AGAP009789 / 3292064	VectorBaseID:	AGAP009789	Length:	440	Species:	Anopheles gambiae

Alignment Length:	509	Identity:	115/509 - (22%)
Similarity:	190/509 - (37%)	Gaps:	130/509 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    51 RSFFLGSFVTALIITVHLISNIYVKWD---STPVIIGISPQ----ATSILKVPFPAITICNMNQV 108
            |.|:|...|.::..:|.|   .:|.|:   |...::.|...    .||:     |::|||.:.::
Mosquito     1 RLFWLVLIVVSIYFSVVL---SFVSWERYQSKSTVVAIEKDHYYWNTSM-----PSLTICPLKRI 57

  Fly   109 QRSLVANYREGSNESALLKLLCESDSWESSEADEEFSASNFVT-NNLKISEFVSNHSQSCERMLL 172
            .|..:.||   .:::.:.|   |.|..|..:..|..:.|.|:. .|:|       ||.:.:.:|
Mosquito    58 YRPYLLNY---CSKNGITK---EEDQAELFDFLESLANSTFINFENIK-------HSDNVDSLL- 108

  Fly   173 FCRFSAVERNCSQLFQQILTDEGLCCVFNFQPPEYLYKPFANNNRNLTNSDGFE---SVMWDPES 234
                                     .|...||..|: |...|..|:||..|..|   ....:.|.
Mosquito   109 -------------------------DVLQIQPENYM-KIIYNLTRDLTRLDDTELRVRTQSNLEF 147

  Fly   235 GYPEQLPPKFYPATASGTGITLGFTAVL-----DAEMGEYYCSST----------NG-------- 276
            ....|...::.....:.:.|:...||.|     :..:.::|.:.|          :|
Mosquito   148 LRTHQTLTEYGICYTTNSFISSNLTASLLLTGRELPLDDFYSTRTVHNVRYGNLFDGDITYSFIG 212

  Fly   277 --PGFKVYFHNPIEV-------PKVKEAGLISAIGYETNYRIEMVRAEAVPAIRSISRDGRQCLF 332
              |...:::|:|.|.       |...||.     .||| :.||:|..:......:||:.|  |.|
Mosquito   213 FEPPITIFYHSPYETLNIAKYQPLTNEAH-----EYET-FSIEIVTTKDFKEDTTISQRG--CRF 269

  Fly   333 KNEKELIFYRIYTRLNCENECLAAFLYDTCSCIPFDHPLIYSNA-SICSMGD-TSCVRRAQR--- 392
            ..|..|..|.|||:..|..||.....|..|.|||..:|.....| .:|.... ..|..|.|:
Mosquito   270 HYESNLTHYSIYTKGICLQECRIQLAYKLCGCIPHFYPNPGPRAKKVCHYKQLIKCFPRYQKLFL 334

  Fly   393 -----ASNRPGW-AKCRQQCLPSCFDLNYLASGFSFPLASNNFQLANALVESFNKSYLSKNIAVI 451
                 .:::.|. ..|.|.|:.|...:.:          ....:....|:.|.....:.|...::
Mosquito   335 EFKQDINDKKGIPCYCEQNCVDSKVIIEH----------RQVLKQTQKLIGSIGGLIVVKRYPLV 389

  Fly   452 NVYFRESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISLAEILYFLILKPL 505
            . :.|:.::         ..|:.|.::||..|.|:||||:.:.|||||..|:.|
Mosquito   390 R-FSRQLLF---------TFTDLLVSIGGTAGFFLGFSVLGMVEILYFFTLRLL 433

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	111/501 (22%)
ppk12	NP_611672.1	ASC	29..499	CDD:279230	111/501 (22%)
AgaP_AGAP009789	XP_553643.3	ASC	1..427	CDD:279230	111/501 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820