Protein Alignment ppk12 and Scnn1g

DIOPT Version :9

• Sequence 1: NP_611672.1
• Gene: ppk12 / 37566
• FlyBaseID: FBgn0034730
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_035456.1
• Gene: Scnn1g / 20278
• MGIID: 104695
• Length: 655
• Species: Mus musculus
• Alignment Length: 618
• Identity: 112/618 - (18%)
• Similarity: 199/618 - (32%)
• Gaps: 162/618 - (26%)

  Fly    33 TSLHGLKFVGDSGLSSWERSFFLGSFVTALIITVHLISNIYVKWDSTPVIIGISPQATSI----L 93
            |:.||.:.:..| .....|..::...:||:.:.:         |....::......:.||    .
Mouse    36 TNTHGCRRIVVS-RGRLRRLLWIAFTLTAVALII---------WQCALLVFSFYTVSVSIKVHFQ 90

  Fly    94 KVPFPAITICNMNQVQRSLVANY---REGSNESALLKLLCESD-----------------SWESS 138
            |:.|||:||||:|..:.|.|::.   .:...:.|||.|....|                 :||.:
Mouse    91 KLDFPAVTICNINPYKYSAVSDLLTDLDSETKQALLSLYGVKDVLDSTPRKRREAGSMRSTWEGT 155

  Fly   139 -------------EADEEFSASNFVT-NNLKIS----------------------EFVSNHSQSC 167
                         ..:|:..|.:|.| ...|||                      :..||.:..|
Mouse   156 PPRFLNLIPLLVFNENEKGKARDFFTGRKRKISGKIIHKASNVMHVHESKKLVGFQLCSNDTSDC 220

  Fly   168 ERMLLFCRFSAVER-------------------NCSQLFQQILTD---EGLCCVFN----FQPPE 206
            .........:|::.                   |.|...:::|..   :|:.|...    |..|.
Mouse   221 ATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGMSCDARNFTLFHHPM 285

  Fly   207 YLYKPFANNNRNLTNSDGFESVMWDPESGYPEQLPPKFYPATASGTGITLGFTAVLDAEMGEYYC 271
            |......||..|.|                        ..:|:.| |...|...:|.....||..
Mouse   286 YGNCYTFNNRENAT------------------------ILSTSMG-GSEYGLQVILYINEDEYNP 325

  Fly   272 SSTNGPGFKVYFHNPIEVPKVKEAGLISAIGYETNYRIEMVRA-EAVPAIRSISRDGRQCLFKNE 335
            ...:..|.||..|...|.|.:::.|........|:..:.:..: :........:.||......|
Mouse   326 FLVSSTGAKVLVHQQNEYPFIEDVGTEIETAMSTSIGMHLTESFKLSEPYSQCTEDGSDVPVTN- 389

  Fly   336 KELIFYRIYTRLNCENECLAAFLYDTCSCIPFDHPLIYSNASICSMGDTSCVRRAQRASNRPGWA 400
               |:...|:...|...|....:.:.|.|..:..||..: |:.|:.            ...|.|.
Mouse   390 ---IYNAAYSLQICLYSCFQTKMVEKCGCAQYSQPLPPA-ANYCNY------------QQHPNWM 438

  Fly   401 KCRQQ---------------CLPSCF--DLNYLASGFSFPLASNNFQLANALV----ESFNKSYL 444
            .|..|               |..||.  :.....|...:|..::...|.|.|.    :..||...
Mouse   439 YCYYQLYQAFVREELGCQSVCKQSCSFKEWTLTTSLAQWPSEASEKWLLNVLTWDQSQQINKKLN 503

  Fly   445 SKNIAVINVYFRESVYYGNTKNAYVGLTEFLSNVGGVMGLFMGFSVISLAEIL--YFLILKPLAE 507
            ..::|.:.:::::.......::....:...|||.||.:||:|..||:.:.||:  :|:....:..
Mouse   504 KTDLAKLLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDFFSIIA 568

  Fly   508 LFVWKRSSHVDSEKSLKHNAFGIEKGQSSDNPS 540
            ...|:::....:.:....:.......|..|||:
Mouse   569 RRQWQKAKDWWARRRTPPSTETPSSQQGQDNPA 601

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	106/575 (18%)
		ASC	29..499	CDD:279230	106/575 (18%)
Scnn1g	NP_035456.1	ENaC	24..636	CDD:273304	112/618 (18%)
		deg-1	32..557	CDD:273309	106/572 (19%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	582..636		4/20 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842237
Domainoid	1	1.000	108	1.000	Domainoid score	I6420
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm8693
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.650