Protein Alignment ppk12 and mec-4

DIOPT Version :9

• Sequence 1: NP_611672.1
• Gene: ppk12 / 37566
• FlyBaseID: FBgn0034730
• Length: 569
• Species: Drosophila melanogaster
• Sequence 2: NP_510712.2
• Gene: mec-4 / 181728
• WormBaseID: WBGene00003168
• Length: 768
• Species: Caenorhabditis elegans
• Alignment Length: 672
• Identity: 116/672 - (17%)
• Similarity: 212/672 - (31%)
• Gaps: 215/672 - (31%)

  Fly    27 RQFLNQTSLHGLKFVGDSGLSSWERSFFLGSFVTALIITVHLISNIYVKWDSTPVIIGISPQATS 91
            ::|..:||.||:..:|::. :.:.|:.::..|:..:|:......::..|::....|:.|.
 Worm    85 KEFCYKTSAHGIPMIGEAP-NVYYRAVWVVLFLGCMIMLYLNAQSVLDKYNRNEKIVDIQ----- 143

  Fly    92 ILK---VPFPAITICNMNQVQRSLVANY---------------REGSN----------------- 121
             ||   .||||||:||:|..:.||..:.               :.|.|
 Worm   144 -LKFDTAPFPAITLCNLNPYKASLATSVDLVKRTLSAFDGAMGKAGGNKDHEEEREVVTEPPTTP 207

  Fly   122 --------------------ESALLKLLCESD-SWESSEADEEFSASNFVTNNLKI--------- 156
                                |....:.||.|. |.|..:.|||.......|...|:
 Worm   208 APTTKPARRRGKRDLSGAFFEPGFARCLCGSQGSSEQEDKDEEKEEELLETTTKKVFNINDADEE 272

  Fly   157 ----SEFVSNHSQSCE-------RMLLFCR----------------FSAVERNCSQLFQQIL--- 191
                .|:.:.|.::.:       .|:..|:                ..|.:|:....:...|
 Worm   273 WDGMEEYDNEHYENYDVEATTGMNMMEECQSERTKFDEPTGFDDRCICAFDRSTHDAWPCFLNGT 337

  Fly   192 --------------------TDEG-----------LCCVFNFQPP-----EYLYKPFANNNRNLT 220
                                |.:|           .|..:|.:.|     .||.......:.|..
 Worm   338 WETTECDTCNEHAFCTKDNKTAKGHRSPCICAPSRFCVAYNGKTPPIEIWTYLQGGTPTEDPNFL 402

  Fly   221 NSDGF--------------ESVMW-------------------------------DPESGYPEQL 240
            .:.||              |::|:                               |.|:.:...:
 Worm   403 EAMGFQGMTDEVAIVTKAKENIMFAMATLSMQDRERLSTTKRELVHKCSFNGKACDIEADFLTHI 467

  Fly   241 PPKFYPATASGTGITLGFTAVLDAEM----------GEYYCSSTNGPGFKVYFHNPIEVPKVKEA 295
            .|.|..........|:..|::....|          ...|..:|...|.::..|:..:.|.....
 Worm   468 DPAFGSCFTFNHNRTVNLTSIRAGPMYGLRMLVYVNASDYMPTTEATGVRLTIHDKEDFPFPDTF 532

  Fly   296 GLISAIGYETNYRIEMVRAEAVPA-IRSISRDGR--QCLFKNEKELIFYRIYTRLNCENECLAAF 357
            |..:..||.:::.:.:.:...:|| ......||:  ..::.|.:       |:...|...|....
 Worm   533 GYSAPTGYVSSFGLRLRKMSRLPAPYGDCVPDGKTSDYIYSNYE-------YSVEGCYRSCFQQL 590

  Fly   358 LYDTCSCIPFDHPLIYSNASICSMGDTSCVRRAQRASNRPGW------AKCRQQCLPSCFDLNYL 416
            :...|.|.....| :..||..|...|....:......|..|.      .:|:|.|..|.:.:.|
 Worm   591 VLKECRCGDPRFP-VPENARHCDAADPIARKCLDARMNDLGGLHGSFRCRCQQPCRQSIYSVTY- 653

  Fly   417 ASGFSFPLASNNFQL--ANALVESFNKSYLSKNIAVINVYFRESVYYGNTKNAYVGLTEFLSNVG 479
             |...:|..|...||  .|......||.| .:|.|::.|::.:..:...|::...|....|::.|
 Worm   654 -SPAKWPSLSLQIQLGSCNGTAVECNKHY-KENGAMVEVFYEQLNFEMLTESEAYGFVNLLADFG 716

  Fly   480 GVMGLFMGFSVISLAEILYFLI 501
            |.:||:.|.|.::..|.::..:
 Worm   717 GQLGLWCGISFLTCCEFVFLFL 738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	116/667 (17%)
		ASC	29..499	CDD:279230	116/666 (17%)
mec-4	NP_510712.2	deg-1	86..736	CDD:273309	116/667 (17%)
		ASC	87..>172	CDD:279230	25/91 (27%)
		ASC	<428..739	CDD:295594	59/322 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160162327
Domainoid	1	1.000	106	1.000	Domainoid score	I4100
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100105
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X60
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.650